1V64


Conserved Protein Domain Family
HMG-box_UBF1_rpt3
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cd22000: HMG-box_UBF1_rpt3 
Click on image for an interactive view with Cn3D
third high mobility group (HMG)-box found in upstream-binding factor 1 (UBF1) and similar proteins
UBF1, also called UBTF, nucleolar transcription factor 1, or auto-antigen NOR-90, is a nucleolar transcription factor that recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. UBF1 contains six HMG-box domains. This model corresponds to the third one.
Links
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Statistics
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PSSM-Id: 438816
Aligned: 12 rows
Threshold Bit Score: 107.54
Created: 8-Apr-2019
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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putative DNA
Conserved site includes 20 residues -Click on image for an interactive view with Cn3D
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1          ## #####  ##      #         ##  #  ##      #   #  #   #  #                    
1V64_A        17 PTKPPPNSYSLYCAELMANMKDvp--stERMVLCSQQWKLLSqkEKDAYHKKCDQKKKDYEVELLRFLESLp--EEEQQR 92   house mouse
P17480       297 PTKPPPNSYSLYCAELMANMKDvp--stERMVLCSQQWKLLSqkEKDAYHKKCDQKKKDYEVELLRFLESLp--EEEQQR 372  human
P25980       297 PTKPPPNSYSMYCAELMANMKDvp--stERMVLCSQRWKLLSqkEKDAYHKKCEQRKKDYEVELMRFLENLp--EEEQQR 372  African clawed...
AAH55140     297 PTKPPPNGYSLYCAELMVNMKDvp--stERMVLCSKQWKMMTqkEKDAFQKRCEQKKKQYEIDLQRFLESLp--DEERER 372  zebrafish
POI19923     121 PTKPPPNSYSLYCAELMANMKDvp--stERMVLCSQQWKLLSqkEKDAYHKKCDQKKKDYEIELLRFLEVSg--IPGRSP 196  Chinese bamboo...
XP_014347912 431 PTKPPPNGYSLYCAELMVNMKDvp--stERMVLCSKQWKIMSqkDKDSYQKRCEQKKKQYETDLQRFLESLp--DEERDR 506  coelacanth
XP_007899718 295 PTKPPPNGYSLYCAELMSNMKDip--stERMVLCSKQWKMLSqkEKDAYQKRCEQKKKEYEIDLHRFLQSLp--VHEQQR 370  elephant shark
XP_019628383 424 PDKPPPNGYSLFCQELMLKLTDvp--nkERMQECSRRWKTMSqkEKDGYQKKAEELKTSFEFDFQRYLETLs--PEDKER 499  Belcher's lanc...
PIK39428     320 PTRPPMNGYSLFCSHFMKLKNElt--stQRMQACSKEWKKLSdkDRMEYNTRTVQAKKEYFENLEKYVLTLp--PEEAAK 395  Japanese sea c...
NP_001071845 287 PKRPPSNGYNLFCTETMSQFTTmq--sqKRIVECGRLWNLKSaeEKQKYHQRFIQMKQQYEKKLQEFYQSLspeRRKEEE 364  vase tunicate
XP_022091128 312 PSKPPANAYNLFCSEMLKQMGHmgsntrAKMMECSALWSDTDlkKKQEYKERVEKLKSQYKKELEKYIESLp--EGERAK 389  crown-of-thorn...
XP_002738418 352 PDRPPPNGYSLFCSILMNEHLShip-snERMVECSKRWKTLSqqEKDLYQERSNAAKKEFAIKYEEYLEKLp--EEEREK 428  Saccoglossus k...

Feature 1               
1V64_A        93 VLGEEKM 99   house mouse
P17480       373 VLGEEKM 379  human
P25980       373 VLAEEKM 379  African clawed frog
AAH55140     373 VMGEEKL 379  zebrafish
POI19923     197 TRCAGCL 203  Chinese bamboo-partridge
XP_014347912 507 VLIEEKL 513  coelacanth
XP_007899718 371 VLGEEKM 377  elephant shark
XP_019628383 500 VLAEEKG 506  Belcher's lancelet
PIK39428     396 YQSELAA 402  Japanese sea cucumber
NP_001071845 365 LKDKGQK 371  vase tunicate
XP_022091128 390 YMPELEA 396  crown-of-thorns starfish
XP_002738418 429 LLKEDKS 435  Saccoglossus kowalevskii

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