Conserved Protein Domain Family
HMG-box_PB1
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cd21984: HMG-box_PB1 
high mobility group (HMG)-box found in protein polybromo-1 (PB1) and similar proteins
PB1, also called BRG1-associated factor 180 (BAF180), or polybromo-1D, is a subunit of the PBAF (polybromo/Brg1-associated factor) chromatin-remodeling complex required for kinetochore localization during mitosis and the transcription of estrogen-responsive genes. It is involved in transcriptional activation and repression of select genes by chromatin remodeling. It acts as a negative regulator of cell proliferation.
Links
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Statistics
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PSSM-Id: 438800
Aligned: 23 rows
Threshold Bit Score: 101.547
Created: 8-Apr-2019
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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putative DNA
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1         ## #####  ##      #           ##  #  ##      #   #  #   #  #
Q86U86       1380 KINMSGYILFSSEMRAVIKAQHPDysFGELSRLVGTEWRNLEtaKKAEYEERAAKVAEQQ 1439 human
PIK53005     1191 NRSASGFILFASEIRAQVKDSNPNksFGEISRLCGLEWHKLTaeDKVRYEERAAILAESR 1250 Japanese sea cucumber
XP_013063123 1348 RRQPSGYILFAGEIRKQISQDNPScsFGDISKIVGTKWRALSkaEKDVFEEKARKLADDV 1407 Biomphalaria glabrata
EEC07487     1318 KRVVTGYLLFSSEIRKSIVQSNPDrsFGDISRLVGNEWRNLQgpQKADYEERALRLSSED 1377 black-legged tick
XP_030511659   35 RQLLTGYIIYASEIRKQVIDKNPNqnFGDISRLVGNEWKALPhdIRSKYDQRALIHNKRV 94   Rhodamnia argentea
XP_009010782 1528 VRNITGYIVYAGECRKDIQAEFPDfnFGDISRAVGNRWKSLPkdQKEKYEEKARLLASDA 1587 Helobdella robusta
XP_013402941 1080 NRKPTGYIIYAAEVRKKLKDQHPDysFGELSKVVGNNWKSLPdeEKRRYEEKAKKQAEIN 1139 Lingula anatina
PRD20896       76 KRIVTGYILFASEVRRSVIAANPDrsFGDISRLIGTEWRNLPvsKKADYEERAQKQNEET 135  Trichonephila clavipes
PVD24349     1259 RRQPSGYIVFAGEIRKAIQNENPDssFGDISRIVGLKWRTLSkeDKEKYEERAKRIAEDM 1318 Pomacea canaliculata
KFD52911     1367 ARSKSGYILFSAVVRKRIMAENPDcsFGDISKIVGSEWKKLSdeEKKRYEEEAQRIADQR 1426 pig whipworm

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