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first beta-defensin domain found in gallinacin-11 (Gal-11) Gal-11, also called beta-defensin 11, or vitelline membrane outer layer protein 2 or vitelline membrane outer layer protein II (VMO-II or VMOII), is an antimicrobial peptide of the chicken egg. It is one of four major proteins in vitelline membranes, along with ovomucin, lysozyme, and VMO-1. Gal-11 has bactericidal activity toward both Gram-positive and Gram-negative bacteria. Gal-11 is a compact fold composed of 2 packed beta-defensin domains with motifs CX6CX5CX9CX6CC and CX6CX6CX7CX6CC, respectively; this model corresponds to the first one.
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Jiyao W et al.(2023). "The conserved domain database in 2023.",