Conserved Protein Domain Family
CrtA-like

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cd21650: CrtA-like 
spheroidene monooxygenase and similar proteins
Spheroidene monooxygenase (such as Rhodobacter sphaeroides monooxygenase CrtA) catalyzes the asymmetrical introduction of one keto group at the C-2 position of spheroidene and two keto groups at the C-2 and C-2' positions of spirilloxanthin in carotenoid pathways. Spectroscopic analysis suggests CrtA may have a 5-coordinated heme at its active site and that it may be a novel oxygenase and not a P450 enzyme.
Links
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Statistics
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PSSM-Id: 412060
Aligned: 248 rows
Threshold Bit Score: 112.665
Created: 30-Sep-2020
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P17055         3 VASLSLFRFdg-tsSLPWVISQMILSRr--pLNDEPRVk----FYKLCGSGTGEGFtp---kPNWRVWAIMAAFdTEADA 72  Rhodobacter cap...
OJU85748       2 IASLDLARFp----FGVAEREALALRRa---GRRSEAS-----FSRLLLPMRLETMpl--plPRMTLAYWFALWpDEVAL 67  Solirubrobacter...
WP_143120601  15 IMSLHLAEV-----SPGKAMSALRSGPv---PAQHEGLhwastFLMSPLRADSAMFd-----VKPSGAALLAAWdNDEAL 81  Streptomyces alni
WP_071927944   2 TVSFRLASYp----ARGWTGLLANLPRinqeLCATPGLv----AGRVFGTGNLQPPig--gaPIFRRWALFTMFeSDSAR 71  Nocardia mangya...
WP_138947623   2 TMSLHLVRHtsrnaISLWRRRRVLLAE----LDRDPGIa----AARMMASIDLRAVtg--gtPRLRQAALLIEWkDRASR 71  Gordonia araii
WP_033189194   3 FITIDVYDHp---pGGALRWGRATKAAl---RNGIPGL-----RSATVNHSNHATHeli-pkMIPGGRALIAAWdSDRAA 70  Rhodococcus
WP_055576587   7 FLTVDVYDRp---pRGPWLWSRSVKVAl---QQNIPGL-----RAVTVNHSNHLTHqlgpssFLPPGRALIAAWdSPESA 75  Mycobacterium g...
KQY63772       6 FVTVDAFDRp----AGGRIRWRRNLRRv--lDGGIEGL-----RGASVNYSNNATHtvp-pgLLPGGCALVAAWeSPEAA 73  Nocardioides sp...
PTW72331       6 FVTVDVFDRpp--gGRIRWRRDLKRTL----DGGIPGLrg--aSVNVANDGTRSLVp----hVLPGGTALVAAWeSPGAA 73  Nocardioides sp...
WP_146175291  11 HVTLDIVHL-----APLAARRWHAAARam-lAARPPGLrg-gvVVRCNRGTRGSGLp----lLVPGGRGVVLGWdDPAAA 79  Conexibacter sp...
P17055        73 RDVTANHPVwkrwra----haaetLVLHLQPLSARGTWGGVNPFlpeqvaepspDEPVVALTRAAIKPHKan-aFWSRVP 147 Rhodobacter cap...
OJU85748      68 QRFRAGPLRrwdr-------arerLALTLRPVQAFGAWGGADPLager--sepaPGPVVLLTHSRTRVAKls-rFLVTDR 137 Solirubrobacter...
WP_143120601  82 DRYLSHSSAaay---------dngFRARFEPVRTIGAWPGLLELprre--ipvdDHPVGVLTLARVRMNKmv-pFVAAAS 149 Streptomyces alni
WP_071927944  72 DDFENSCAVdiftdr----srelwQVAMAPTRIGRGEWRGWRPEvdpv--phtdDEPVVSFTYSHVRSRYvp-tFLLNNK 144 Nocardia mangya...
WP_138947623  72 DERFADAVWpssyaaeareawsvaLDTARVLRSDSPNWSPSVDGvaq----lrpDEPMAALTFGGVHPRYvp-aFNQGNR 146 Gordonia araii
WP_033189194  71 RNAFRGPLRpvleddr--rfsldgEIVRVRLQESHHTWHGWVPSdegag-svakSDPLVVVVHGVLKPRHlarfVANNVH 147 Rhodococcus
WP_055576587  76 LAAFRGPLAcavqspg--rysldgEVVRARVEHAGDHWHGWNPSdegst-aissDEPLVVIVHGILKPRHll-gFVKNNV 151 Mycobacterium g...
KQY63772      74 EAAFAGPLRraidgpdrfsldgeiVRVRIDSESERDNWHGWEPRadgaq-plekDEPMVAIVHGILRRGEli-tFVRNNV 151 Nocardioides sp...
PTW72331      74 EAAFAGPLRravdgpgrfsldgevVRVKIGSESERAHWHGWAPSaegae-plvdEEPMVAIVHGIIRRGRll-eFVRNNV 151 Nocardioides sp...
WP_146175291  80 AEAWQRHGAglava-----perrfSADAEVRRVREQDWHGWRPVagga--pardDEPAIALVHALLRPSAvv-pFSQANR 151 Conexibacter sp...
P17055       148 KISEKVgeDQNLMFKIGIGEIPlf-hQVTFSIWPDVAKMNAFARgd--tpHGKAIRAAREEGWFTEELYARFRLlgteGS 224 Rhodobacter cap...
OJU85748     138 GVVRELrrAGGRLWSDGFVDDParldSGTVSIWRDTAAATAFAYap--gvHQRAVKAQRDGAWFPESWFGRFAIeaaeGS 215 Solirubrobacter...
WP_143120601 150 HAERDAahHPAFLEGTSLIKPPn--qVATFSLWRSVKEMRQYTVgsypggHVRAMKRHEEQDFHHETIFVRLRPyavdGH 227 Streptomyces alni
WP_071927944 145 RVVDEQrtDAGLIAQLGVADDLt--sTSTFSIWRSQHDLIDFAYrs--seAHKKVIKPSLTQWQFDNFSARFRIhssaGT 220 Nocardia mangya...
WP_138947623 147 NVLRELddNSDETFRTGVQDGPl--gFGTFTLWRSQAAMTRFAYrt--ptHDGTRKRSEEQGWTHGQLFVRFRPvasrGT 222 Gordonia araii
WP_033189194 148 AASRAAh-HPGHRGSVDISSNLpf-eHTSVSLWESLGAAIDYAYpp--ggHASAMKYAQQQDTHRAGVFLRIRPtastGS 223 Rhodococcus
WP_055576587 152 HAASRAafHPGHRGSVDISSQLpf-eHTSVSLWKTAKLARDYAYap--ggHAQAMEHARTTDTHRMGVYLQVRPlassGS 228 Mycobacterium g...
KQY63772     152 HAASRAahHPGHRGSVDISAQLpf-eHTSISLWKTYELAQDFAYrp--ggHASAMKHALKKKTHRVGVFLQARPtactGA 228 Nocardioides sp...
PTW72331     152 HAASRAahHPGHRGSVDISSQLpy-eHTSISLWKTYALAYDFAYkk--ggHASAMTHALRENTHRVGVFLQVRPlastGT 228 Nocardioides sp...
WP_146175291 152 RAVAHArdREALVATTALMRGSll-eATSLSCWSTAGAMREYAYrp--ggHADAMRGSQANTWHRRRCFVHLRPvaasGG 228 Conexibacter sp...
P17055       225 WMGKD 229 Rhodobacter capsulatus SB 1003
OJU85748     216 WRGLP 220 Solirubrobacterales bacterium 70-9
WP_143120601 228 WSGRN 232 Streptomyces alni
WP_071927944 221 WDGRD 225 Nocardia mangyaensis
WP_138947623 223 WQGRD 227 Gordonia araii
WP_033189194 224 LGLES 228 Rhodococcus
WP_055576587 229 LGLDS 233 Mycobacterium gordonae
KQY63772     229 LGIDQ 233 Nocardioides sp. Root140
PTW72331     229 LGLDK 233 Nocardioides sp. CF204
WP_146175291 229 LPGGP 233 Conexibacter sp. Seoho-28
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