Conserved Protein Domain Family
RRM2_Crp79_Mug28

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cd21621: RRM2_Crp79_Mug28 
RNA recognition motif 2 (RRM2) found in Schizosaccharomyces pombe mRNA export factor Crp79, meiotically up-regulated gene 28 protein (Mug28) and similar proteins
Crp79, also called meiotic expression up-regulated protein 5 (Mug5), or polyadenylate-binding protein crp79, or PABP, or poly(A)-binding protein, is an auxiliary mRNA export factor that binds the poly(A) tail of mRNA and is involved in the export of mRNA from the nucleus to the cytoplasm. Mug28 is a meiosis-specific protein that regulates spore wall formation. Members in this family contain three RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains). The model corresponds to the second RRM motif.
Statistics
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PSSM-Id: 410200
Aligned: 9 rows
Threshold Bit Score: 116.269
Created: 25-Feb-2020
Updated: 17-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9P6M8        205 LSILNLPaEVTPIDLYNHFkq---aGVVKGTAVSQFLDqRGFRYGEVIMDSvESCQNAIEKLNNvpYKGSILEVSIK 278  fission yeast
XP_002174442  209 LNVLNLPtDTTPIELYQYFke---aGTVKGTAISQFRDyRGYRCGEVIMESvEDCNEAIRRFNGcaFRGSILEVGMK 282  Schizosaccharomy...
XP_018226797  196 LSVFNLPyEMTPKDLFCLFse---lGRVEGAFIYNVVDsRGRRVGEVAMGSfYHAKKALESLNNttLNGYILELAFK 269  Pneumocystis car...
Q9UT83        272 IGILNLPlKVSPVELYNEFsn---hGHILGVAINQSINeDMTHYAEVAVSTyESCIEIIEKFHAiaYEGSILQLFIK 345  Schizosaccharomy...
XP_002172720  163 IGILNFPtNVTPLQLYNDFkk---hAKIVGTAINQAPPnSESTYAEVLIPTyYDCIQLLEYYKEyeYHDRKLDFFVK 236  Schizosaccharomy...
XP_019025240  232 LTVNSLPpTLTPKELYTIFmdrvpdIKIEGTFIYAVPDvRGLRFGEVNFLHeMDAEKSLKMCNGlvVGGYQLEVSYK 308  Saitoella compli...
XP_013016360  263 IGILNVPkQTSPVDLYEDFsq---yGKILGAAINQTPNpDQTLYAELAVNShEDCSKIIASFKNflYKGTQLQFFVK 336  Schizosaccharomy...
CCX09203      224 LTVANLPqDMCPKTFYNLFse---vGPVEGCYIWPHVDhMGRRYAHIVMNSfFVAQKAVEYFHGrpINGYPLDVTYF 297  Pyronema omphalo...
OLL23749      194 ITVANLPaDMAPRDLYSLLen---fGRVEQSFIFAYGDaKGRRFGEGLMAThYAAQKALETLNGhvFKGCMLEVGYK 267  Neolecta irregul...
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