6G90,5UZ5


Conserved Protein Domain Family
RRM_SNP1_like

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cd21615: RRM_SNP1_like 
Click on image for an interactive view with Cn3D
RNA recognition motif (RRM) found in Saccharomyces cerevisiae U1 small nuclear ribonucleoprotein SNP1 and similar proteins
SNP1, also called U1 snRNP protein SNP1, or U1 small nuclear ribonucleoprotein 70 kDa homolog, or U1 70K, or U1 snRNP 70 kDa homolog, interacts with mRNA and is involved in nuclear mRNA splicing. It is a component of the spliceosome, where it is associated with snRNP U1 by binding stem loop I of U1 snRNA. Members in this family contain an N-terminal U1snRNP70 domain and an RNA recognition motif (RRM), also called RBD (RNA binding domain) or RNP (ribonucleoprotein domain).
Statistics
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PSSM-Id: 410194
Aligned: 16 rows
Threshold Bit Score: 163.252
Created: 19-Feb-2020
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
 
RNA binding
Conserved site includes 31 residues -Click on image for an interactive view with Cn3D
Feature 1:RNA binding site [nucleic acid binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                # ##                                                    #  ####         
6G90_B        89 LQNWNPNVDPHIkd-------------------------------------------tDPYRTIFIGRLPYDLDEIELQK 125 baker's yeast
5UZ5_A        89 LQNWNPNVDPHIkd-------------------------------------------tDPYRTIFIGRLPYDLDEIELQK 125 Saccharomyces c...
Q00916        89 LQNWNPNVDPHIkd-------------------------------------------tDPYRTIFIGRLPYDLDEIELQK 125 Saccharomyces c...
SMN19930      88 LRQWDPTNDIHMaq-------------------------------------------tDPFRTIFVGRLPYNITEVDLQK 124 Kazachstania sa...
CDO93084      98 VQEWHPESDPNIs--------------------------------------------gDPYRTLFVGRLNYSVDEVELQK 133 Kluyveromyces d...
OEJ84234     101 LREWNPHEDIYSks-------------------------------------------tDPYKTLFVGRLPYDLGEVELSK 137 Hanseniaspora o...
ODV84828      71 LSNYNPDLDLNIv--------------------------------------------gDPYKTIFVGRLPYNTNELKLSS 106 [Candida] arabi...
XP_013934083  84 LLKWNPETDTNIa--------------------------------------------gDPYKTVFVGRLDYTVNEIELRE 119 Ogataea parapol...
ANZ75536     105 LAAWNPEKDLNMi--------------------------------------------gDASRTIFVARLDYNSTEVDLQN 140 Komagataella pa...
XP_009492150  46 LCKDNPVPPLPEgtpvwvnadtrralkksihdsqvkqeidrgteeyknrpqdspeyssDAFKTLFVGRLPYSLNEAGLSG 125 Fonticula alba
Feature 1                   # ####     ### #                                      #  # #####     
6G90_B       126 YFVKFGEIEKIRIVKDKitqKSKGYAFIVFKDPISSKMAFKEIgvhrg------------iqikDRICIVDIERGRTVKY 193 baker's yeast
5UZ5_A       126 YFVKFGEIEKIRIVKDKitqKSKGYAFIVFKDPISSKMAFKEIgvhrg------------iqikDRICIVDIERGRTVKY 193 Saccharomyces c...
Q00916       126 YFVKFGEIEKIRIVKDKitqKSKGYAFIVFKDPISSKMAFKEIgvhrg------------iqikDRICIVDIERGRTVKY 193 Saccharomyces c...
SMN19930     125 AFGNYGSIEKLRVVRDRe-sKSKGYGFVVFVDPMAAKTVTRECgvhrg------------ieigGRRCIVDIERGRTTKY 191 Kazachstania sa...
CDO93084     134 SFIKYGEIESCRIVRDKe-gKSRGYGFVQFTDYEDSKQCFRALgvrrg------------leimGRTSIVDIERSRTVKF 200 Kluyveromyces d...
OEJ84234     138 HFTKFGEIANFRLVKDVktgKSRGYGFITYKSEISLRKAFDEVgesgv------------liinDRPVIVDFERGRTVHY 205 Hanseniaspora o...
ODV84828     107 IFNQFGEIDSIKLITDKytnKSKGYAFIVYKTIESAKLAYQKGnglki------------dddsERKCIVDYERGRIVKN 174 [Candida] arabi...
XP_013934083 120 KFAQFGEIDQIRVVRDTntgKSRGYAFILYKSESDAKLAFQKGnrm---------------vikDRAVIVDIERGRVVKN 184 Ogataea parapol...
ANZ75536     141 SLGVFGEIDRIRVVRDVntdKSKGYGFVVFKQPEDARTAYRNSssl---------------tinNRPVLVDIERGRTVKN 205 Komagataella pa...
XP_009492150 126 HFEKFGRIRFCRIVRCKrtgKSRGYGFIEFSSSSDLTRAFREGdsmhiraniegyyepgetpspDRTCVVDVERGRTVAN 205 Fonticula alba
Feature 1        # ###   ###  
6G90_B       194 FKPRRLGGGLGGR 206 baker's yeast
5UZ5_A       194 FKPRRLGGGLGGR 206 Saccharomyces cerevisiae S288C
Q00916       194 FKPRRLGGGLGGR 206 Saccharomyces cerevisiae S288c
SMN19930     192 FTPRRLGGGLGGR 204 Kazachstania saulgeensis
CDO93084     201 FKPRRLGGGLGGR 213 Kluyveromyces dobzhanskii CBS 2104
OEJ84234     206 FKPRRLGGGLGGR 218 Hanseniaspora osmophila
ODV84828     175 WKPRRLGGGLGGR 187 [Candida] arabinofermentans NRRL YB-2248
XP_013934083 185 WKPRRLGGGLGGR 197 Ogataea parapolymorpha DL-1
ANZ75536     206 WKPRRLGGGLGGR 218 Komagataella pastoris
XP_009492150 206 WLPRRLGKGLGST 218 Fonticula alba

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