Conserved Protein Domain Family
RRM1_PES4_MIP6

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cd21601: RRM1_PES4_MIP6 
RNA recognition motif 1 (RRM1) found in Saccharomyces cerevisiae protein PES4, protein MIP6 and similar proteins
The family includes PES4 (also called DNA polymerase epsilon suppressor 4) and MIP6 (also called MEX67-interacting protein 6), both of which are predicted RNA binding proteins that may act as regulators of late translation, protection, and mRNA localization. MIP6 acts as a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores. It interacts with MEX67. Members in this family contain four RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains). The model corresponds to the first RRM motif.
Statistics
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PSSM-Id: 410180
Aligned: 12 rows
Threshold Bit Score: 132.085
Created: 25-Feb-2020
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P39684        91 VPLFIGDLHetVTEETLKGIFKKYpSFVSAKVCLDsvTKKSLGHGYLNFEdkeEAEKAMEELNYtkVNGKEIRIMPSLRN 170  Saccharomyces ...
XP_003673837  92 TSLFINGLAddVTENMLYDVFSKYqSLVSLKICCDsdSKKSLNYGYLNFSdelEAKKAVDDFNYtiLFGNEIKMMPSLRN 171  Naumovozyma ca...
BAP69624     213 TALFIGDLPgnVTEDMLGNIFNKFkSFTSVKICVDsnTKKSLGYGYLNFGdqdDAEKAVDEYNYmpIFGREIRMMPSLRN 292  Kluyveromyces ...
GAV55401     102 IALFIGDLDeqIDERILTEIFKKFkSLASVKVCTDseTGRSLGHGYLNFLkrqDTLKVIEEFNYkpIFGKEVRIMPSLRN 181  Zygosaccharomy...
SCU90973      97 TALFIGDLNldVTEKMLKYVFGVFpSLQSVKICVDaeTKRSLGYGYLNFSaaeDAKKAIEDFNYvkLFGKEVRIMPSMRN 176  Lachancea meye...
XP_003980256 101 TPLYIGGLSkdVTEETLFEAFEDYkTLASIKICRDsvTNESLGYGYLNFSnsvEATKLIDDYNYtnLFGNEIKIMPSMRN 180  Naumovozyma da...
CDH12287      98 IALFIGDLDkrVTEETLANLFGKYeSLVSVKVCKDteTGKSLGYGYLNFRqkmDTLAAIDEFNYrpILDREVRIMPSLRN 177  Zygosaccharomy...
CUS21005      95 SSLFIGDLDkgVTEKMLLDTFSNFkSLASVKICLDseTKLSLGYGYLNFTsaqEADEAIEKFSYvkLFGKEVRIMPSMRN 174  Lachancea queb...
XP_003681020  97 VALFIGDLEpsVTENMLRDIFGKFrSLTSVKICLDsnSGKSLGYGYLNFAnseDAEKATEEFNYrpIEGQEVRIMPSLRN 176  Torulaspora de...
NP_984845    116 VALFIGDLDekVTEKNLRDTFNKFdSFVSAKICIDsnTKKSLGYGYLNFSneeDAERVIEEFNYipIFGREVRIMPSLRN 195  Eremothecium g...
XP_003956566  89 EALFIGNLDkdVTEKQLETIFSVYpSFISAKVCYNssTNLSLGHGYLNFGskeDAEKACEEMNYskVLNNEIRIMPSMRD 168  Kazachstania a...
P38760       111 NSLFIGNLKstVTEEMLRKIFKRYqSFESAKVCRDflTKKSLGYGYLNFKdknDAESARKEFNYtvFFGQEVKIMPSMKN 190  Saccharomyces ...
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