5HYC,5HXL


Conserved Protein Domain Family
DLC-like_SpDlc1-like

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cd21456: DLC-like_SpDlc1-like 
dynein light chain (DLC)-like domain found in Schizosaccharomyces pombe dynein light chain Tctex-type (SpDlc1) and similar proteins
Schizosaccharomyces pombe dynein light chain 1 (SpDlc1) belongs to the 14-kDa Tctex-1 dynein light chain family. It acts as a non-catalytic accessory component of a dynein complex. It is required for regular oscillatory nuclear movement and efficient recombination during meiotic prophase in fission yeast. The model corresponds to the dynein light chain (DLC)-like domain found in SpDlc1 and similar proteins.
Statistics
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PSSM-Id: 412004
Aligned: 14 rows
Threshold Bit Score: 137.876
Created: 28-Jan-2020
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
 
trimer
Conserved site includes 36 residues -Click on image for an interactive view with Cn3D
Feature 1:trimer interface [polypeptide binding site]
Evidence:
  • Structure:5HYC; Pyricularia oryzae hypothetical protein MGG_01005 homodimer interacts with MoDyn1I2, contacts at 4A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                # #  ##  #   #   #   #                 ##########       
5HYC_A         8 PIPTNRLKQIAADACNDAIgsaefYDHAKTEQWNHQIINTILKAVIAESqpsds---ttppqFKFAVNSTIVQHlvpssk 84  Pyricularia ory...
Q9UTS6         4 PIDSKKLEEICLEAAQPVLka-seYDGDKTAEMNQSVIYAVLNALNKETq-----------sYKWIVSSTLVQKlped-- 69  Schizosaccharom...
Q0UTE9         5 PLPTSELEQLAAHACESVIgasetYDHSKVSDWNTSIIQTILKTLIEKTsttttagepsqppYKYIINSTVIQHigvpse 84  Parastagonospor...
XP_018225048  10 PILYENLKELCESRLCSILgd-asYTECQAETWNTEIIHSLLEGLKTYAp-----------rYKWIVTSSIIEKssn--- 74  Pneumocystis ca...
SEI30963      15 PLPQSKLTEMIDSAASSVVat-egYSHNDTSKWNSQIIAKILDALKDESk-----------gYKFLVHSTLVEVtd---- 78  Yarrowia lipoly...
CDO51512      20 PIPVLTLGKICDEVCTDVFdnvrnYDHEKSTAWNNEIIQLVLKGIEKESsa---------qnYKYIVYVTTIERvsdaps 90  Geotrichum cand...
GAD96664       6 PVPTTELTKLATEACDNALksvegYDHAKVGSWNSEIINHILQSLIKATtpstp---ntpppFRFTVNSTIVQQglvdks 82  Byssochlamys sp...
XP_002172620   4 PLSREKIDAICSEAVTSLLke-pvYEHDTILKLNKEAIRFVLSALNKDAs-----------sYKWIVNSTVVQKlpag-- 69  Schizosaccharom...
XP_016215019   5 PLPESRLKQIAQDACNTALgtstaYNHSLTPTWNDTIISTILQTLISETaspsg----eapsFKFMVNSTIIQHtaptga 80  Verruconis gall...
PHH55011      13 PIAVSRLTEIATMACEKAIgnakcYDHPKTAEWNNTIINTILETCIEETkamkk---gknprYKFVCNSSIVQHtapsed 89  Ceratocystis fi...
Feature 1                                   ############   # #   #           #     ##
5HYC_A        85 lnkpaggaddkpastatstdgkphvgrRGMHSATGAFWNdKTDGMWTYKHEGdeskGMDVVVMLIWIA 152 Pyricularia oryzae 70-15
Q9UTS6        70 ------------------------hpsRGVHAAHAACWNcEKDGMTTIKESGe---AIDVVLSIMWIS 110 Schizosaccharomyces pombe 9...
Q0UTE9        85 ---------------------pekhgrRGMHSAVGAYWNnEKDGTYSYKWEGaqkkGMDIVIAITWVA 131 Parastagonospora nodorum SN15
XP_018225048  75 -------------------------isLGIHSVQGAYWNnEKDGMLRYEWSNq---YLRVVLGMSWIQ 114 Pneumocystis carinii B80
SEI30963      79 -------------------------hrPGIKSSTGGFWNtEKDGVWNYKWSNd---KVDVLVSIAWIH 118 Yarrowia lipolytica
CDO51512      91 ---------------------esdspsRGIRTSSGGFWNpEKDGMWNHKWTTsg-tNIDVVFSIAWIH 136 Geotrichum candidum
GAD96664      83 t-------------------tsgdagkRGMHSASGAFWDvNRDGMWTFKYPGgeqrGLDVVVSVTWFA 131 Byssochlamys spectabilis No. 5
XP_002172620  70 ------------------------hptAGVTASQAASWDcERDGFLVVKKSSp---VVGITLTITFVS 110 Schizosaccharomyces japonic...
XP_016215019  81 kdd----------------nstanagrRGMHSAAGAYWNnEKDGMWSYKYEGgekrGMDVVVMVMWVA 132 Verruconis gallopava
PHH55011      90 dddddddete-egaelkekeykssggrRGMHSATAAYWDdAQDGMWSFKYDGaaskGLDIIIMLVWVH 156 Ceratocystis fimbriata CBS ...

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