4DND,1LVF


Conserved Protein Domain Family
SNARE_NTD_STX6_STX10
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cd21443: SNARE_NTD_STX6_STX10 
N-terminal domain of syntaxin-6, syntaxin-10, and similar proteins
This subfamily includes two soluble NSF attachment protein receptor (SNARE) proteins, syntaxin-6 (STX6) and syntaxin-10 (STX10). STX6 is involved in intracellular vesicle trafficking. STX10, also called Syn10, is involved in vesicular transport from the late endosomes to the trans-Golgi network. This model corresponds to the N-terminal domain of STX6 and STX10, which is a regulatory domain named Habc.
Links
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Statistics
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PSSM-Id: 410569
Aligned: 44 rows
Threshold Bit Score: 78.4169
Created: 6-Feb-2020
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4DND_A        27 DPFFVVRGEVQKAVNTARGLYQRWCELlqesa---------------avgreELDWTTNELRNGLRSIEWDLEDLEETIG 91  human
PAA69638      13 DPFLLDQREVELTLHRLEEAVSVWRTMqkerrtd-----------fsdsleyELQGVESSIRNGIRDVKWSLEDLEETLK 81  Macrostomum lig...
XP_004998963   6 DPYFVVKEEVENSIANAERLYARWQRMftsrs----------------addaEFKHTTEQLKTNIKSIEWDLEDLAETVS 69  Salpingoeca ros...
XP_003389021   5 DPFYTVRDDVRESLNNAQDLYSRWCMLledq-----------------sdleKTQGVSTDLRSCIKSIEWDLQDLDETIS 67  Amphimedon quee...
KOO24089       3 DPYLAVREEVENSVRVVVELHTKWLSLdsk--------------------sdNFEWTSSELLSGLRAIEWDLQDLEDTVS 62  Chrysochromulin...
PAA52557       3 DPFLLDQAALEARLTALQETFERWREIrdcrdva-----------efvakadEFNWLLVEISQGIKNAGWDLDDLEETLK 71  Macrostomum lig...
PAA66777       3 DPFLLDQNRIEGQIELLTPNFERWRQLrdgdlppag-------teereevneEYRYLTNELSTSVRSIGWEIDDLQETLS 75  Macrostomum lig...
PAA71117      36 DPFSVDQQALEEKLKALQRSFDRWRALksadshehgdgdraadavpadllqdEFRWLTDELVRSLKSLTWELNDLHETLR 115 Macrostomum lig...
PAA70738       5 DPFQLDQQALDNKLKLLQESLERWRRVkidagelts-------qeelqeaedEFNWLREEIGKSVKSIGWDLDDLAETLR 77  Macrostomum lig...
Q54PW2         6 DPFNLMEKSVSESIININKIYNKWYSLlnetn---------------tfsnkKFKFYTKEINRMINDIEIDLNDISNSMK 70  Dictyostelium d...

4DND_A        92 IVEa---NPGKFklp-agDLQERKVFVERXREAVQEXKDHXV 129 human
PAA69638      82 LMSq---NNGRFvt--seDLAARRKFLEESRKTLADVEFEVS 118 Macrostomum lignano
XP_004998963  70 IAMr---EPHKFnls-qsELSNRNDFIETSKQKLKALKDGTS 107 Salpingoeca rosetta
XP_003389021  68 VVEa---NPQKFrvs-tgEIETRKQFIRDTRQVINKMKSHMS 105 Amphimedon queenslandica
KOO24089      63 IVEg---NRIKFqld-egDMNARKEFIETTRRQIVTIRNEVQ 100 Chrysochromulina tobinii
PAA52557      72 MMS----ESRQLsis-eaDHRNRRQFIENARQLLSQISAETF 108 Macrostomum lignano
PAA66777      76 LMLk--aNSPALas--asSRDNRSAFLVRVRSFIDEVAREVA 113 Macrostomum lignano
PAA71117     116 SMLqh-qPPGSQqs--asLTDNRRLFISNTRALLASIESEVQ 154 Macrostomum lignano
PAA70738      78 RMS----EQNRQpa---eETTARGEYIRRMRHLLTTIDDEVK 112 Macrostomum lignano
Q54PW2        71 IIEnnnnKNEKFknipkqEIQRRNEFLKESKNEINNIKIKLS 112 Dictyostelium discoideum AX4
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