Conserved Protein Domain Family
CH_TAGLN3

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cd21281: CH_TAGLN3 
calponin homology (CH) domain found in transgelin-3
Transgelin-3, also called neuronal protein 22 (NP22), or neuronal protein NP25, may have a role in alcohol-related adaptations and may mediate regulatory signal transduction pathways in neurons. It contains a single copy of the CH domain. CH domains are actin filament (F-actin) binding motifs.
Statistics
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PSSM-Id: 409130
Aligned: 4 rows
Threshold Bit Score: 247.953
Created: 7-Oct-2019
Updated: 25-Oct-2021
Structure
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Aligned Rows:
 
putative actin
Feature 1:putative actin binding site [polypeptide binding site]
Evidence:
  • Comment:Based on the structure evidence that Homo sapiens filamin-A binds F-actin.

cd21281 is part of a hierarchy of related CD models.
Use the graphical representation to navigate this hierarchy.
cd21281 is a member of the superfamily cl00030
cd21281 Sequence Cluster
Sub-family Hierarchy
cd00014CH_SFcd21183CH_FLN-like_rpt1cd21227CH_jitterbug-like_rpt1cd21228CH_FLN_rpt1cd21308CH_FLNA_rpt1cd21309CH_FLNB_rpt1cd21310CH_FLNC_rpt1cd21311CH_dFLNA-like_rpt1cd21184CH_FLN-like_rpt2cd21229CH_jitterbug-like_rpt2cd21230CH_FLN_rpt2cd21312CH_FLNA_rpt2cd21313CH_FLNB_rpt2cd21314CH_FLNC_rpt2cd21315CH_dFLNA-like_rpt2cd21185CH_jitterbug-like_rpt3cd21186CH_DMD-like_rpt1cd21231CH_DMD_rpt1cd21232CH_UTRN_rpt1cd21187CH_DMD-like_rpt2cd21233CH_DMD_rpt2cd21234CH_UTRN_rpt2cd21188CH_PLEC-like_rpt1cd21235CH_PLEC_rpt1cd21236CH_DYST_rpt1cd21237CH_MACF1_rpt1cd21189CH_PLEC-like_rpt2cd21238CH_PLEC_rpt2cd21239CH_DYST_rpt2cd21240CH_MACF1_rpt2cd21190CH_SYNE-like_rpt1cd21241CH_SYNE1_rpt1cd21242CH_SYNE2_rpt1cd21191CH_CLMN_rpt1cd21192CH_SYNE-like_rpt2cd21243CH_SYNE1_rpt2cd21244CH_SYNE2_rpt2cd21245CH_CLMN_rpt2cd21193CH_beta_spectrin_rpt1cd21246CH_SPTB-like_rpt1cd21316CH_SPTBN1_rpt1cd21317CH_SPTBN2_rpt1cd21318CH_SPTBN4_rpt1cd21247CH_SPTBN5_rpt1cd21194CH_beta_spectrin_rpt2cd21248CH_SPTB_like_rpt2cd21319CH_SPTB_rpt2cd21320CH_SPTBN1_rpt2cd21321CH_SPTBN2_rpt2cd21322CH_SPTBN4_rpt2cd21249CH_SPTBN5_rpt2cd21199CH_CYTScd21256CH_CYTSAcd21257CH_CYTSBcd21200CH_SMTN-likecd21258CH_SMTNAcd21259CH_SMTNBcd21260CH_SMTNL1cd21261CH_SMTNL2cd21201CH_VAVcd21262CH_VAV1cd21263CH_VAV2cd21264CH_VAV3cd21202CH_PIXcd21265CH_alphaPIXcd21266CH_betaPIXcd21203CH_AtKIN14-likecd21204CH_GAS2-likecd21267CH_GAS2cd21268CH_GAS2L1_2cd21269CH_GAS2L3cd21205CH_LRCHcd21270CH_LRCH1cd21271CH_LRCH2cd21272CH_LRCH3cd21273CH_LRCH4cd21206CH_IQGAPcd21274CH_IQGAP1cd21275CH_IQGAP2cd21276CH_IQGAP3cd21207CH_dMP20-likecd21208CH_LMO7-likecd21277CH_LMO7cd21278CH_LIMCH1cd21209CH_TAGLN-likecd21279CH_TAGLNcd21280CH_TAGLN2cd21281CH_TAGLN3cd21210CH_SCP1-likecd21211CH_CNNcd21282CH_CNN1cd21283CH_CNN2cd21284CH_CNN3cd21212CH_NAV2-likecd21285CH_NAV2cd21286CH_NAV3cd21213CH_DIXDC1cd21214CH_ACTN_rpt1cd21215CH_SpAIN1-like_rpt1cd21216CH_ACTN_rpt2cd21287CH_ACTN1_rpt2cd21288CH_ACTN2_rpt2cd21289CH_ACTN3_rpt2cd21290CH_ACTN4_rpt2cd21291CH_SpAIN1-like_rpt2cd21217CH_PLS_FIM_rpt1cd21292CH_PLS_rpt1cd21323CH_PLS1_rpt1cd21324CH_PLS2_rpt1cd21325CH_PLS3_rpt1cd21293CH_AtFIM_like_rpt1cd21294CH_FIMB_rpt1cd21218CH_PLS_FIM_rpt2cd21295CH_PLS_rpt2cd21326CH_PLS1_rpt2cd21327CH_PLS2_rpt2cd21328CH_PLS3_rpt2cd21296CH_AtFIM_like_rpt2cd21297CH_FIMB_rpt2cd21219CH_PLS_FIM_rpt3cd21298CH_PLS_rpt3cd21329CH_PLS1_rpt3cd21330CH_PLS2_rpt3cd21331CH_PLS3_rpt3cd21299CH_AtFIM_like_rpt3cd21300CH_FIMB_rpt3cd21220CH_PLS_FIM_rpt4cd21301CH_PLS_rpt4cd21332CH_PLS1_rpt4cd21333CH_PLS2_rpt4cd21334CH_PLS3_rpt4cd21302CH_AtFIM_like_rpt4cd21303CH_FIMB_rpt4cd21221CH_PARV_rpt1cd21304CH_PARVA_B_rpt1cd21335CH_PARVA_rpt1cd21336CH_PARVB_rpt1cd21305CH_PARVG_rpt1cd21222CH_PARV_rpt2cd21306CH_PARVA_B_rpt2cd21337CH_PARVA_rpt2cd21338CH_PARVB_rpt2cd21307CH_PARVG_rpt2cd21223CH_ASPM_rpt1cd21224CH_ASPM_rpt2cd21225CH_CTX_rpt1cd21226CH_CTX_rpt2cd22198CH_MICAL_EHBP-likecd21195CH_MICAL2_3-likecd21250CH_MICAL2cd21251CH_MICAL3cd21196CH_MICAL1cd21197CH_MICALLcd21252CH_MICALL1cd21253CH_MICALL2cd21198CH_EHBPcd21254CH_EHBP1cd21255CH_EHBP1L1
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1        #   #                                                         # ##  ## #     
Q9UI15     23 DADLENKLVDWIILQCAEDIehpppGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKIseskMAFKQMEQISQFLKAAET 102 human
NP_956014  23 DPELESRLEDWIVAQCGGNVekpqpGKQNFQNWLMDGTILCRLINSLYPRGKEPIKKIsetqMAFKQMEKISQFLQAAEA 102 zebrafish
GCF50901   23 DPELESRLVDWIIVQCGENIeqpppGRQHFQKWLMDGTLLCKLINSLHPRGKEPIPKIseskMAFKQMEQISQFLKAAEI 102 Paroedura picta
ACO09231   23 AVDLETRLVEWIIIQCGGDIdrpqpGRENFQDWLKTGTILCRLINSLYPPSDKPIKKIpetkMVFKQMEKISQFLQAAEA 102 rainbow smelt
Feature 1         #########     # ## ##  ##  #       
Q9UI15    103 YGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDD 141 human
NP_956014 103 YGVITTDIFQTVDLWEGKDMAAVQRTLMALGSVAITKDD 141 zebrafish
GCF50901  103 YGVRTTDIFQTVDLWEGKDMAAVQRTLLALGSEAVTRDD 141 Paroedura picta
ACO09231  103 YGVIKTDLFQTVDLWEGKDLAAVQRTISALGSIALTKDD 141 rainbow smelt

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