6L6G,6L6H


Conserved Protein Domain Family
Lpg0189-like
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cd21108: Lpg0189-like 
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Legionella pneumophila Lpg0189 and similar proteins
Lpg0189 is a type II secretion system (T2SS)-dependent exoprotein of Legionella pneumophila and related Legionellales, encoded by the lpw02811 ORF. Homologs of this protein are present within ~65% of Legionella species and are absent from non-Legionella species.
Links
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Statistics
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PSSM-Id: 439145
Aligned: 19 rows
Threshold Bit Score: 383.154
Created: 13-Oct-2021
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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homodimer
Conserved site includes 22 residues -Click on image for an interactive view with Cn3D
Feature 1:homodimer interface [polypeptide binding site]
Evidence:
  • Structure:6L6G: Legionella pneumophila Lpg0189 forms homodimer; contacts at 4A
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                        
6L6G_A         6 TDGLIFSPLPqn--------kNTVVRHYSNEQexpnlsqxaqRTIDFPTQIVRVSGNLtglelsCDDVENEIDQVFSKKI 77  Legionella pneu...
RUR18879      21 MDSVPTRQVTvvk------gtHSITRHYTHSKqpl----sgdRTINYPTQVVRITGAIetpnttCEDVFKEIEHLYIDYL 90  Legionella sp. ...
WP_028373001  26 NIFIQNIKTPk----------HTIIKQQTNVQmifknpalmvRTTEYPTQIVRVGGELdnstltCDEVEKEIDSFFSNQI 95  Legionella lans...
WP_058527014  15 SGFANIAELPkeemvaaglseHTVVRQYTNFQdvadhkqwfaRHQPYPTQVVRVQGDLgge-rhCEAVLKEIDDFFVSRI 93  Legionella erythra
WP_045095050  24 TDTMIFSEQPag--------kHSVVHSYSNESvlpnqestveRSIDFPTQIIRISSSLkdqqvdCDQVNLIIDKILIQNI 95  Legionella fall...
WP_018577493  25 TDKLRFLQNPvs--------kNTIVNTYSNESeglnqlqsltRTVDFPTQIIRISNELkgkeitCEQVNAQIEETVFSHI 96  Legionella shak...
WP_010946607  25 KGDVFLSKIPts--------kNAFVKSYSSESthlkllepnaRSIDYPTQIVRVSGSLesqqldCDQVHEEILEKVVAPF 96  Legionella pneu...
WP_018576292  23 QNIPNIIRKP-----------GAIIKHYVSSDeaferlgqgkRTIDFPTQIIRISGTVneanlsCDDVFNTINYDYLGFV 91  Legionella shak...
WP_058479194  26 NKGQIFFKAPen--------kNTQVKSYANDSkhlkegetftRSLDYPTQIIRISGSLetsvmdCDRVFAEVEDRLISHI 97  Legionella walt...
WP_058535748  25 LQIMSLTQTPe---------kNTQTMSYSNESaapsqlklltRSIEYPTQIIRMESEIkdqqisCNEVHNQINKILVDNI 95  Legionella saou...

Feature 1                                                                            #  # # # #  
6L6G_A        78 Spn-lfTYNTYVSCGYDvndpeqHAINFSIQSYFDPltDNAVDYLKSYLKEYNGYNLfnttTLQIENAKGIIVSXNLNAG 156 Legionella pneu...
RUR18879      91 SdsrmyYLNSYTFCRFDpk--teLANQFIISSYFDPanDKAVSELTEWLETMKGAEIyg-hPFTVESAKELIVSLKISSG 167 Legionella sp. ...
WP_028373001  96 Khd-lfYYNTLIMCGYDpk--tnYAIRYSIQSYFDPlnDKGIEYLQSYLAEHNGKMLlg-wPFYVEDAQGVVVSMSMNAG 171 Legionella lans...
WP_058527014  94 The-kfFYNTLVFCGYDpk--teYAVHFAINSYFDPlnDGAIYYLENYLGSHNGQDLlg-vPFEVESAIGVAVSLNIDAG 169 Legionella erythra
WP_045095050  96 Tpd-kfTYNIYIVCEYDpe--tnFAIDFKLHSYFDPinDKAVEYLKSYLSEYNGADFlg-tKLNIESAKGLVISLNIIAG 171 Legionella fall...
WP_018577493  97 Tsd-kfIYNILISCGYDpd--tnYATSFFINSYFDPktDEAIDYLKDYLSQNNGTDFlg-tKLNIESAKGVVIALNIAAG 172 Legionella shak...
WP_010946607  97 Tpd-kfTYNTYISCSYNpd--tnMATGFLINSYLDPltDDAVELLETYLAKNNGSNLlg-tPLTFEPAKALVVALTISAG 172 Legionella pneu...
WP_018576292  92 IdsgktTYNSYVYCGFNpe--teKAERFSISTYFDPltDSAVDEVKEWLEVMNGTDLyg-tPFVIESARELVISLRVSAG 168 Legionella shak...
WP_058479194  98 Tpd-kySYMTYISCTYDpe--tnFATGFAISSFFDPmtDTAVEELNKFLDEYNGSDLlg-tKLTIESARAVIAALNISAG 173 Legionella walt...
WP_058535748  96 Tne-hfIYALYISCHYDpq--tfLAKQFIINSYFDPvnDEAVAYLENYLHEYNGSNLlg-tQFKIEPAKGLIISLSFAAG 171 Legionella saou...

Feature 1                ####  # # # #                                     #                 # # 
6L6G_A       157 LKsnpdktPFTLYRQDRNNFYFksNFDVRKELISDIYQRFYSNdPDXILPFFDKWIFsYAGSVYYSILxaSNYLELQPER 236 Legionella pneu...
RUR18879     168 FKegisdpNLLVYRTDTSNLLFanNYQMKKELVDDIRHRFYSYePKVILSFLEHWFFpGLGGIYQRVLasSNYVLLEPHR 247 Legionella sp. ...
WP_028373001 172 RKnghndsTMLVLRHDNANHYFanNYQLLKELVADIHQRYNSNnPELILPFLDRWFFsFAGMVYERILknSTYTELQPER 251 Legionella lans...
WP_058527014 170 VLnhrndsTLIRYLHDNQSHFFasNYDLMKELIQDIYERFYSNdPDLILPFLNRWFYsYADRTYDSILsrVNYVELQPER 249 Legionella erythra
WP_045095050 172 FKknpntpPFLEYRKDRNNFYFksNYEMKNKLIADIYQNFFSNdPDVILPFINKWFYtYADTIYKAVLrdANYVELQPER 251 Legionella fall...
WP_018577493 173 MKkkpntpPFIEYQQDRSNFYFssNYEMSNKLFTDIYQNFFSNdPEKILPFLDRWVFsFAGSVYQAALkdSNYVELQPER 252 Legionella shak...
WP_010946607 173 MKknpnkpPFVEYKQDRSNFYFksNYEMRNKLFTDIYQNFFTNdPNKILPFLDKWIFvNASSVYEAILmdSNFVELQPER 252 Legionella pneu...
WP_018576292 169 VKesekdpNLLVFKTQTSNHYFktDYQMKQELMADIKNQFYSLdSRVVLPFFAKWFYpSSEATYNRVLhaSNYVYLEPER 248 Legionella shak...
WP_058479194 174 FKknvdkpPFIEYRQDRSNFYFksNYEMKKTFISDIYQNFFSNdPEKVLPFLDRWIFpNAGSYYKAILwdSNYVQLQPER 253 Legionella walt...
WP_058535748 172 MKknpikpPFTEYRRDRSNFYFksNYEMKNKLFTDVYENFYSNsADKVLPFLDKWLFaNAGSLYKGILrdSNYAELQPER 251 Legionella saou...

Feature 1        #     ## # #   #                 
6L6G_A       237 IFVXEnEGDIFVSDLRYYFANLCxKRNPNKHCL 269 Legionella pneumophila subsp. pneumophila str. Philadelphia 1
RUR18879     248 IFVMKqEPQLFTPMFNIDFAHQC-FESKTKFCL 279 Legionella sp. km535
WP_028373001 252 IFLMEkEPKIFSSALKYYFANHC-SKYPNKHCL 283 Legionella lansingensis
WP_058527014 250 LFLMDkEPKVYTSPLRMYFAHHC-AKYENKHCL 281 Legionella erythra
WP_045095050 252 IFLMEsGNEIFVSDLKYYFIHNC-NKYENKRCL 283 Legionella fallonii
WP_018577493 253 IFLMDnGEKIFVSGLKYYFSHVC-ERHENHRCL 284 Legionella shakespearei
WP_010946607 253 IFLMEnGEQIFVSNLKYYFTHNC-NRYSNHRCL 284 Legionella pneumophila
WP_018576292 249 IFLMDkEPKIFSPMIKMTYAHSC-FNSPSKFCL 280 Legionella shakespearei
WP_058479194 254 IFLMDsGQNIFVSNLKFYFSHNC-NNYSNHRCL 285 Legionella waltersii
WP_058535748 252 IFLMEnGETIFVSGLKQYFTNHC-EKYDNHRCL 283 Legionella saoudiensis

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