3EQ5


Conserved Protein Domain Family
DHD_Sno
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cd21084: DHD_Sno 
Dachshund-homology domain found in Ski-like protein (Sno) and similar proteins
Ski-like protein, also known as SKIL, Ski-related oncogene (Sno), or Ski-related protein, is the ski proto-oncogene homolog. It may have regulatory roles in cell division or differentiation in response to extracellular signals. The Dachshund-homology domain (DHD), also known as the N-terminal Ski/Sno/Dac domain, adopts a mixed alpha/beta structure containing a helix-turn-helix motif, similar to features found in the forkhead/winged-helix family of DNA binding proteins. It contains a conserved CLPQ motif and can bind co-factors. Its structure suggests that it may also bind DNA.
Links
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Statistics
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PSSM-Id: 410787
Aligned: 7 rows
Threshold Bit Score: 191.713
Created: 12-Feb-2019
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3EQ5_A        24 PSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAP 103 human
P12757       137 PSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAP 216 human
NP_001124141 116 PPDSSTDLSMCSLEGESISCFSVGGELRLCLPQLLNTILRDFSLQQINSVCDQLYLYCSRCDATQLHILKVLGILPPGTP 195 zebrafish
XP_007901861 143 PSDSSTDLTHTSLEGETISCFVVGGEKRLCLPQVLNSVLRDFSLQQINTVCDELYIYCSRCTAEQLQILKVLGILPFNAP 222 elephant shark
NP_990505    140 PPDSSTELTQTVLEGESISCFKVGGEKRLCLPQVLNSVLRDFSLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAP 219 chicken
XP_018119195 119 PSDSSTELTQTDLEGESISCFMVGGEKRLCLPQVLNSVLRDFSLQQINIVCDEMYIYCSRCTSDQLHILKVLGILPFNAP 198 African clawed ...
XP_005992797 145 PSDSSTELTQTLLEGEAISCFMVGGEKRLCLPQVLNSVLRDFSLQQINTVCDELYIYCSRCTADQLQILKVLGILPLNAP 224 coelacanth

3EQ5_A       104 SCGLITLTDAQRLCNALLRP 123 human
P12757       217 SCGLITLTDAQRLCNALLRP 236 human
NP_001124141 196 SCGLITLTDAQRLCNTLLHP 215 zebrafish
XP_007901861 223 SCGLITQTDAQRLCNALIHP 242 elephant shark
NP_990505    220 SCGLITLTDAQRLCNALLRP 239 chicken
XP_018119195 199 SCGLITLTDAQRLCNALLRP 218 African clawed frog
XP_005992797 225 SCGLITLTDAQRLCNALLRP 244 coelacanth
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