2LC3


Conserved Protein Domain Family
BTHB_HectD1
?
cd21062: BTHB_HectD1 
Click on image for an interactive view with Cn3D
basic tilted helix bundle (BTHB) domain found in HECT domain-containing protein 1 (HectD1) and similar proteins
HectD1, also called E3 ligase for inhibin receptor (EULIR), is a Hect-type E3 ubiquitin transferase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. HectD1 is required for development of head mesenchyme and neural tube closure.
Links
?
Statistics
?
PSSM-Id: 439138
Aligned: 20 rows
Threshold Bit Score: 90.8046
Created: 27-Nov-2018
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
2LC3_A         15 CWSIEHVEQylg-----tdeLPKNDLITYLQKNADAAFLRHWKLTGTNKSIRKNrNCSQLIAAYKDFCEHG 80   human
XP_019636568 1876 RWTVEFVERalg-----tddLPKSELISYLQQNADTAFLRRWKLTGAPKSIRKNrNCAQLVAAYKEFLGSG 1941 Belcher's lancelet
ADB22404      499 RWSISFVELhlg-----sdeLPKSELITYLQRNADIHFLRRWKLTGTPKNIRKNrNCSQLVAAYKEFCGIS 564  Saccoglossus kowalevskii
PIK60002     1144 PWTVSYVERhlg-----terLPKSDVISMMQQYADIPFLRRWKLIGNARSVRKSrNCAKLVAAYKEFVHLG 1209 Japanese sea cucumber
XP_013401335 1917 RWSISYVERhlg-----tdlLPKLEVIDYLRQNADEAFLLRWKLVGTSKNIKKSrNCAQLVAAYKEFCQSG 1982 Lingula anatina
XP_012559409 2043 KWTVEYVKEnig-----sleLPKSDVINYLQQNGTNEFLKKWKLVGSARMCRRQrNCAALFAAYKDYAKFK 2108 swiftwater hydra
XP_011662922 1818 PWTVGFVQRhlg-----terLPKTELIMYLQEKADAQFLRRWKLTSNATNIRRTrNSSRLIAAYREFIQLG 1883 purple sea urchin
XP_009016625 1319 GWPIWQVAQqlg-----talLPKRILINYMQERAPQHFLEKWKLIGADKNVKKChNCSQLTRAYKVSSTHK 1384 Helobdella robusta
PAA64293     2032 EMTPAQVEQslh-----rgsLHKSQVLDYIAASASEDFMREWRLRGSRRNVMRKnNCRKLISAYRQLLKDQ 2097 Macrostomum lignano
OAF69058     1943 EWNVELVRNsltnselnsngPTKADIIKFLQKNASQNLLTEYKLNGSPRVLRRSiSSKDLIGIYDNYVRYE 2013 Intoshia linei
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap