6PDK


Conserved Protein Domain Family
Smlt3025-like

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cd20897: Smlt3025-like 
S. maltophilia immunity protein with unknown function (Smlt3025) and similar proteins
This family includes Smlt3025, an immunity protein of the type IV secretion system (T4SS) found in the multi-drug-resistant opportunistic pathogen Stenotrophomonas maltophilia. Experiments show that Smlt3025 counteracts Smlt3024, an effector protein transferred by the T4SS into target cells. The crystal structure of Smlt3025 reveals a topology similar to the iron-regulated protein FrpD from Neisseria meningitidis which has been shown to interact with the RTX protein FrpC, while its counterpart Smlt3024 is homologous to the N-terminal domain of large Ca2+-binding RTX proteins.
Statistics
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PSSM-Id: 411014
Aligned: 103 rows
Threshold Bit Score: 115.966
Created: 17-Aug-2020
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6PDK_A        27 RTINGHTYTDAPVDVKLGPNTFRIPANYldsqi-apwpgEGVTLVIEWPDMKPTAPgaranp--rtndfrKEIPIRINYV 103 Stenotrophomona...
WP_143144491 543 HSIGGVIVPAGMHGAMLGPHAFVFPEEVfkehyrpssrlKQISFVLRWPSLEPWPEdvymyr--dqdtflSTLPVSVSYL 620 Luteibacter sp....
WP_144913146 513 RLAAASTPTVPTHVVKLGPHRFRLPVNVfngpegfsykgIGFGIALRWPTLEPYPLgvnfhd--tnddfiSSVRIRLSYF 590 Luteibacter yeo...
WP_139980848 518 REPPAEQQATPTKVVNLGPHRFRLPMNLfdgqngfnpgkTEIWMAWSWPELQPLPMgvnyhd--dmtmfiSTIKVGVHHL 595 Luteibacter pin...
WP_089976063 553 MVPFAERTSVSVRGANLGPKRFCLLERLfngpw--rptgNTIGFMLNWPTLEPPPLnfdyma--nqeaflSTLGVSVDWI 628 Luteibacter sp....
WP_090175088 555 FWPPDSMAPEATSSFHLGPHRFCVQQRLfhnli--rasqDRVGFALNWPTLEPLPPdldeda--dqdtfvSTLEIRIDYF 630 Luteibacter sp....
WP_081907403  75 APPDETEAAVPTVDAKLGPHRFRFPKNLyyqqs-vpdsdGGLMLNVQWPSLQPLPMgidyhd--tpehflNNIAIDLDPV 151 unclassified Lu...
WP_090350816  29 APLAPPDKTEATVDAKLGPHRFRFPKNLyyqqs-gpdadGGVMLNVQWPHLRPLPLgvdyhd--sndnfiNHISIDLSTV 105 Dyella sp. 333M...
SFE07003      43 AGQAWTGYSDRPVPARLGPNTFRFPMNLyesqv--gpdrDGARLNLAWPALEALPAgaraaagysetwgsRSIDIDLRYM 120 Dyella marensis
SKB63126     456 PNYKWEGYSEKLVPAKLGPNTFLFPMNLyehqt-gpdfqGSVGFTLRWPTLEAFPAgavrdrayagayldEAISVRPRYV 534 Luteibacter sp....
6PDK_A       104 DrvPVETLLSrlssneait---eegsvergdPRDRLDQRVAKPQTLGLTPYAIdEAKMVVYAKKYEARygkppvrnpaye 180 Stenotrophomona...
WP_143144491 621 D--RLTDEKVhrymrsiiepfdpdgdfgrddPSENLHLRIKGDPVHGLTPYYTdFPALERYYQRLFGPdtpaaepsgyrn 698 Luteibacter sp....
WP_144913146 591 D--RLSDEEAnnfllhhlrygkeaspyirnnPAHNLDMRIQGEPRFGLTPYYLdTERLKAYYTKEFGPnskavihvnewg 668 Luteibacter yeo...
WP_139980848 596 D--ALDDAKYahrlqayiep-hlsdpilrqnPAENLNMRIKGAPVHGLTPYFMdFERLSAFYASLYGPgtpaae-pggln 671 Luteibacter pin...
WP_089976063 629 E--RLSDEAYrqyprnwieplfpndpndlvrPMDNLHLRNKGAPMHGLTPYYAdLPAIRSYFEDRDGPdttag--rperq 704 Luteibacter sp....
WP_090175088 631 D--KLTDEEArvlplrwvqplrpnhpedrkrPDDNLDLRIMGAPVHGLTPYYAdLPAIRRYYQDLYGHdtrag--lpdtq 706 Luteibacter sp....
WP_081907403 152 K--QLTDAEYqthlrrsvepvdpgdprqrmhPATNLDQRIEQNPIYGLTPYYVdFDRFRIYYMKRYGErarpp--tpsqn 227 unclassified Lu...
WP_090350816 106 E--HLSDDQYrallrrmiepldpekptpsekVLDDLSARIQGDTSHGLTRYSVdFEKFRDFYITTYGThvrpp--dpiqn 181 Dyella sp. 333M...
SFE07003     121 ErpLLDALLPalinegppg----rsfaapddPAQHRSLRIEGEPVHGLTPYYAdPGKLAAYFRAHGIDasgdn--larng 194 Dyella marensis
SKB63126     535 DkvPIEDVVRtsisphp--------wnqpddPIYHLSLRTKGGAVDGLVPYYIdMAKLKAYLSRRGAPvdden--ltglg 604 Luteibacter sp....
6PDK_A       181 RDWYIARQGdGRISSFIKCDgeefrrdgvrlegrevisepgevaaGCVHYFVDiDNKLSVSLDYKRafLKDWKRMEEAVR 260 Stenotrophomona...
WP_143144491 699 EDWYIDMGPdGIPRTVLKCSpaaipdgvtvtpdglsvirgvferaTCDHHFMLpEYRATVDIMYQRivMADWRRIEDRVR 778 Luteibacter sp....
WP_144913146 669 EDWFLRRGKeGVPLTFVTCStrlrpdgvmvvdqrlidgevgqhraVCTHEFLLaQYKAVVRADYLRimLPDWKKIEARVA 748 Luteibacter yeo...
WP_139980848 672 EDWYLRTDAnGKPLTVIMCDpreipngtyleggrivdapvngrraTCSHVFLLpDYKAIVRIRYQRivLHDWRRIEDLVK 751 Luteibacter pin...
WP_089976063 705 LDWFVDMGPeDIPRTVIKCSvkevpdgvrlehgrlvhqpevfrraTCDHYFLLpEYKATVNLMYQRimMPDWKRIEDRIR 784 Luteibacter sp....
WP_090175088 707 EDWFVDMDEhGIPRTVLKCSvaevpdgvrlvndrlvhdpkifrraTCMHMFAIpEYKSAARITYQRiiAPDWKRIETRVR 786 Luteibacter sp....
WP_081907403 228 ADWFVRMGPhGVPTTFIECSshliqdgarlengrivdardggsrsTCRHQFLIpEYRVVVTLSYLRvvMPNWQRLEAFVR 307 unclassified Lu...
WP_090350816 182 DDWYVHIGVdGIPTTVIKCTpvaqtdgvriesgrivdipgrsrraTCRHQFLVpEYGLLVSLSYPRviLPEWQTMEMFVR 261 Dyella sp. 333M...
SFE07003     195 DDWYLARDEaGRLRTVIVCTsrtiagarligg-klqntppgvergGCRQTFTVpAYGLRISVFYLRayLVDWKRIEERIS 273 Dyella marensis
SKB63126     605 KDWFVSYSTgGKPVTFISCSpreirganlvne-rledtaagidrgTCNQEFVIeEFQIAVNVTYLRayMKDWKRIETRIR 683 Luteibacter sp....
6PDK_A       261 DVIART 266 Stenotrophomonas maltophilia K279a
WP_143144491 779 QLFRDG 784 Luteibacter sp. UNCMF366Tsu5.1
WP_144913146 749 DILRDA 754 Luteibacter yeojuensis
WP_139980848 752 HTLRQA 757 Luteibacter pinisoli
WP_089976063 785 TLLRNG 790 Luteibacter sp. UNCMF331Sha3.1
WP_090175088 787 AILANG 792 Luteibacter sp. UNC138MFCol5.1
WP_081907403 308 KTLKDR 313 unclassified Luteibacter
WP_090350816 262 KTLKAT 267 Dyella sp. 333MFSha
SFE07003     274 GLLERY 279 Dyella marensis
SKB63126     684 SLFDQA 689 Luteibacter sp. 22Crub2.1
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