Conserved Protein Domain Family
PoNe_FilH_TF-like

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cd20731: PoNe_FilH_TF-like 
Polymorphic Nuclease effector (PoNe) co-occurring with N-terminal domains such as filamentous hemagglutinin repeats or TANFOR
The DNase toxin domain called PoNe (Polymorphic Nuclease effector) belongs to a diverse superfamily of PD-(D/E)xK phosphodiesterases, and is associated with several toxin delivery systems including type V, type VI, and type VII. PoNe toxicity is antagonized by cognate immunity proteins (PoNi) containing DUF1911 and DUF1910 domains. This subfamily contains members with PoNe domains typically co-occuring with N-terminal domains such as hemagglutinin repeats and/or hemagglutination activity domains, or a TANFOR domain, which contains uncharacterized single or repeat domains that co-occur with fibronectin type III domains.
Statistics
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PSSM-Id: 410640
Aligned: 15 rows
Threshold Bit Score: 132.907
Created: 5-Sep-2019
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
TXI97791       25 KAGELRETVSNSYFd--rNGFASLDGKCg-----aGNCFDGVYIKGNQ------VIINEVKPLQANGsiklsg------- 84   Aquabacterium...
WP_129001806  710 LTGAKTETLQNYLFen-kMGLTRLDGKVg-----sNNGFDGLFIKGSAtnp-ekIFITECKQQWNAGvtlape------- 775  Filimonas sp....
RZK58609      172 QSGAITESLCDEIFe--tNGFVKFNSKIg-----sNNGFDGVYIKKDGagnvqeIFINEAKQVGSKGnikln-------- 236  Pedobacter sp.
ENV22791       66 KSGILREEIADSYFk--nSGYTKLESKYg------SNCFDGVYMKNGE------LYIVEVKPLKERGsvklsdn------ 125  Acinetobacter...
PRF69495     1500 LQGQAREYVANNYFv--rNGFTPLDGKCg------VNCFDGVYVKGDK------VYINEVKPLNANGsiqln-------- 1557 Burkholderia ...
WP_074724768  105 ASGSKTEALVDDIFq--sQGYTKVDGKYfgd--agSNGFDNVFIKGTIdnp-seIIIIECKQMKQAGnvvlns------- 172  Flavobacteriu...
WP_121458141 2379 EQGALRETVTNGYMt--rNGFTQLEGKCg-----sNKCFDGVFVKGDT------VYIVETKPLQANGaikln-------- 2437 Azonexus fung...
AFD06062      514 AAGKKTEALSDLIFt--rEGFTKQTSKLt-----sDNGFDGVFIKGTLdnp-teIIINEAKQVGSAGnikl--------- 576  Solitalea can...
WP_013622662 2107 QSGKITEGLVEDIMt--aNGYKVGNGRYygdyetaRNGLDGFFYKGDItnp-seIIVIDSKQFKIDGsvklnn------- 2176 Cellulophaga ...
WP_135836044 1491 KGGDLTESIVSEALkkqgYTVTKDLGKYg-----pNNGFDVVAYKGTLdnp-teIMIIEGKQFKQNKildefddvksaqg 1564 Empedobacter ...
TXI97791       85 -----------gnkstdLKTQMSDEWIks-rIDQLLKSGDPAKvqtgnl---ilqssRSGNLTTVVSGVNRN-GMVIVKV 148  Aquabacterium...
WP_129001806  776 ------------nantgLFAQMSDDWIqn-vVERLRNAGKIEQanl--------iegNHAIIEKIVITVNKStGDINLLK 834  Filimonas sp....
RZK58609      237 ------------vrtpnKGPQMSEEWIgq-tINEMIANPNTNVlgml-------lnnNRNKITKTVTGVDKAsSEIVILK 296  Pedobacter sp.
ENV22791      126 -----------kkstndIGVQMSDKWIvs-rTEALVKTKNPDAiktatl--itkavnEGKPINKIVVGVNDS-RAITLNL 190  Acinetobacter...
PRF69495     1558 ------------gpsgdLPTQMSDAWIqr-sIDRLKASGNPELvktadt---iesarANGNLIKVVSGIDSN-GMSLIKP 1620 Burkholderia ...
WP_074724768  173 ------------pastgLPAQMSDDWIky-iAREKLKNLGVDKtklan----tilsnQSSFIQKYVVAVDKTaGEVNFLK 235  Flavobacteriu...
WP_121458141 2438 ------------gpdgdLPTQMTPDWVks-rADALAQTGDPTKkqtaaliqktfdpnSNINLVKIVAGVNEN-GVTLVKL 2503 Azonexus fung...
AFD06062      577 -------------dlpnKGPQMSDAWIda-tIKEMRSNADPITkklgd-----vllnNRNKIIKTVTGIDRStGEILILK 637  Solitalea can...
WP_013622662 2177 -----------gnsstgLPSQMKEDWIry-iADEKLNELKGLQkqtat----aiqnsPAGFIQKYVVAVDKGtGEINFLK 2240 Cellulophaga ...
WP_135836044 1565 ydepsgltinpanpqtgLPTQMSKKWTfehvADKLNKKGGEHKklai-------aleNENIVERFVFAIDKStGAGYFTK 1637 Empedobacter ...
TXI97791      149 K 149  Aquabacterium sp.
WP_129001806  835 L 835  Filimonas sp. TTM-71
RZK58609      297 L 297  Pedobacter sp.
ENV22791      191 G 191  Acinetobacter bereziniae NIPH 3
PRF69495     1621 N 1621 Burkholderia multivorans
WP_074724768  236 L 236  Flavobacterium frigoris
WP_121458141 2504 A 2504 Azonexus fungiphilus
AFD06062      638 L 638  Solitalea canadensis DSM 3403
WP_013622662 2241 L 2241 Cellulophaga lytica
WP_135836044 1638 L 1638 Empedobacter sp. MRS2
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