Conserved Protein Domain Family
CYCLIN_CCNL2_rpt2
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cd20593: CYCLIN_CCNL2_rpt2 
second cyclin box found in cyclin-2 (CCNL2) and similar proteins
CCNL2 is a novel RNA polymerase II-associated cyclin that is involved in pre-mRNA splicing. It may induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors. CCNL2 contains two cyclin boxes. This model corresponds to the second one. The cyclin box is a protein binding domain.
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Statistics
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PSSM-Id: 410296
Aligned: 5 rows
Threshold Bit Score: 267.603
Created: 12-Apr-2019
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q96S94       195 HPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFqPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQ 274 human
Q5BKF8       173 HPHKIIVMYLQVLECERNKHLVQTSWNYMNDSLRTDVFVRFnPETIACACIFLAARTLEIPLPNRPHWFYLFGASEEDIK 252 tropical clawed...
Q5ZJP9       206 HPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFqPESIACACIYLAARTLEIPLPNRPHWFLLFGTTEEEIQ 285 chicken
XP_007905445 166 HPHKIIVMYLQVLECQHNRPLVQTAWNYMNDSLRTDVFVRYnPETIACACIYLAAGALEIPLPNRPHWFLLFGATEEDIK 245 elephant shark
XP_014344025 170 HPHKIIVMYLQVLECERNRHLVQTAWNYMNDSLRTNVFLRFcPETIACACIYLAARTLKIPLPNRPHWFLLFGASENEIQ 249 coelacanth

Q96S94       275 EICLKILQLYARKKVDLthLEGEVEKRKHAIEEAKAQARGLLP 317 human
Q5BKF8       253 EICLQILRLYTRKKADValLENKVEKRKLFIEEAKAKAKGLLP 295 tropical clawed frog
Q5ZJP9       286 EICLKILQLYTRKKVDLsdLESKIEKKKLAIEEAKAQAKGLLP 328 chicken
XP_007905445 246 EICMKILKLYTRKKANLehLDDEVERRKVALQEAKAKAKGLLP 288 elephant shark
XP_014344025 250 EICTKILLLYTRKKVNLkyLESKVEKRKLALEEAKAKAKGLLP 292 coelacanth
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