Conserved Protein Domain Family
CYCLIN_CCNL2_rpt1

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cd20590: CYCLIN_CCNL2_rpt1 
first cyclin box found in cyclin-2 (CCNL2) and similar proteins
CCNL2 is a novel RNA polymerase II-associated cyclin that is involved in pre-mRNA splicing. It may induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors. CCNL2 contains two cyclin boxes. This model corresponds to the first one. The cyclin box is a protein binding domain.
Statistics
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PSSM-Id: 410293
Aligned: 3 rows
Threshold Bit Score: 328.119
Created: 12-Apr-2019
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q96S94  35 VLIGDRLYSGVLITLENCLLPDDKLrFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKS 114 human
Q5BKF8  13 ILIGDKLYSGVMISLENCLMAEERCaLTPSVVDGIDVNTEIDLRCVGCELVQAAGILLRLPQVAMATGQVLFQRFFYTKS 92  tropical clawed frog
Q5ZJP9  46 VLIGDRLYSGVLITLENCLLPEHTLrFTPSMSSGLDPDTETELRVTGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKS 125 chicken
Q96S94 115 FVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKpvPLLLDQDYVNLKNQIIKAERRVLKELGFC 190 human
Q5BKF8  93 FVKHSMEHVAMACVHLASKIEEAPRRIRDVINVFHRLRQLREKQKstPLILDQEYVNLKNQIIKAERRVLKELGFC 168 tropical clawed frog
Q5ZJP9 126 FVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKpvPLILDQEYVNLKNQIIKAERRVLKELGFC 201 chicken
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