Conserved Protein Domain Family
CYCLIN_AcCycT_rpt1

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cd20587: CYCLIN_AcCycT_rpt1 
first cyclin box found in Arabidopsis thaliana T-type cyclins (CycTs) and similar proteins
CycTs associate with their partner cyclin-dependent kinases (CDKs) to trigger their kinase activity. CycTs show high sequence similarity with metazoan cyclin-K (CCNK). CycTs contain two cyclin boxes. This model corresponds to the first one. The cyclin box is a protein binding domain.
Statistics
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PSSM-Id: 410290
Aligned: 7 rows
Threshold Bit Score: 213.535
Created: 11-Jul-2019
Updated: 25-Oct-2021
Structure
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Aligned Rows:
 
putative CDKT-type cyclin
Feature 1:putative CDK interface [polypeptide binding site]
Evidence:
  • Comment:based on the structure of Homo sapiens CCNK in complex with CDK12 (4CXA)

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                        #           #  ## #          
Q8GYM6     49 DSIDLKKETYLRKSYCTFLQDLGMRLKvPQVTIATAIIFCHRFFIRQSHARNDRRTIATVCMFLAGKVEETPRPLKDVIV 128 thale cress
Q9C8P7     23 DGINLKEETFQRWSYTSFLQELGQRLNnPQKTIATAIVLCQRFFTRQSLTKNDPKTVAIICMFIAGKVEGSPRPAGDVVF 102 thale cress
Q9FKE6     49 DGIDLKKETYLRKSYCTFLQDLGMRLKvPQVTIATAIIFCHRFFFRQSHAKNDRRTIATVCMFLAGKVEETPRPLKDVIF 128 thale cress
PNR45325   52 DGIDIKKETYFRKSYCTFLQDLGMRLKvPQVTIATAIVFCHRFFHRQSHKKNDRHMVATICMFLAGKVEETPRPLREVIM 131 Physcomitrella patens
EFJ37217   53 DGIDSRRETYFRKSYCTFLQDLGMRLKvPQVTIATAITFCHRFYLRQSHARNDRFMIATVCMFLAGKVEETPRVLKDVIY 132 Selaginella moelle...
Q56YF8     47 DGIDLKTETRLRDSYCTFLEILGERLKvPQVTIATAIFFCHRFFLRQSHAKNDRQTIATVCMLLAGKVEETPVTLEDVII 126 thale cress
Q8LBC0     50 DGIDLVKESFLRSSYCTFLQRLGMKLHvSQVTISCAMVMCHRFYMRQSHAKNDWQTIATSSLFLACKAEDEPCQLSSVVV 129 thale cress
Feature 1                                #  ###### ##  ###
Q8GYM6    129 VSYEIIHKKDPttaqkikqkEVYEQQKELILNGEKIVLSTLGFD 172 thale cress
Q9C8P7    103 VSYRVLFNKEPl-------rDVFERLKMTVLTGEKLVLSTLECD 139 thale cress
Q9FKE6    129 VSYEIINKKDPgasqkikqkEVYEQQKELILNGEKIVLSTLGFD 172 thale cress
PNR45325  132 FSYEIRFKKDPiaaqrirqkDVYEDQKELVLGGERLLLTTLGFD 175 Physcomitrella patens
EFJ37217  133 VSYTLRNKKDPsannrikqkDLYEAQKQLVLYGERLVLTTLGFD 176 Selaginella moellendorffii
Q56YF8    127 ASYERIHKKDLaga---qrkEVYDQQKELVLIGEELVLSTLNFD 167 thale cress
Q8LBC0    130 ASYEIIYEWDPsasirihqtECYHEFKEIILSGESLLLSTSAFH 173 thale cress

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