Conserved Protein Domain Family
CYCLIN_AtCycB-like_rpt1
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cd20567: CYCLIN_AtCycB-like_rpt1 
first cyclin box found in Arabidopsis thaliana B-type cyclins (CycBs) and similar proteins
Plant B-type cyclins (CycBs) correspond to a group of G2/mitotic-specific cyclins that are functionally linked to S- and M-phases of the mitotic cycle, which predicts their involvement also in meiosis. CycBs associate with their partner cyclin-dependent kinases (CDKs) to trigger the kinase activity. They contain two cyclin boxes. This model corresponds to the first one. The cyclin box is a protein binding domain.
Links
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Statistics
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PSSM-Id: 410270
Aligned: 14 rows
Threshold Bit Score: 253.035
Created: 8-Jul-2019
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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putative CDKB-type cyclin
Feature 1:putative CDK interface [polypeptide binding site]
Evidence:
  • Comment:CDK = cyclin-dependent kinase
  • Comment:Based on the structure evidences that Homo sapiens CCNB1 binds CDK1 and phospho-CDK2
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                            ##  ##  ##  #                                                
Q39068        151 EEPIVDIDVLDSKNSLAAVEYVQDLYAFYRTMERFSCVPVDYMmqQIDLNEKMRAILIDWLIEVHDKFDLINETLFLTVN 230  thale cress
XP_002965711   94 EEPLPNIDEHDVGNQLAVTDYVEDIYSFYRKAEVQSCAAPEYMkqQPEINDKMRAILVDWLIEVHLKFKLMPETLYLTIN 173  Selaginella m...
O48790        110 KDAVIDIDAVDANNELAAVEYVEDIFKFYRTVEEEGGIKDYIGs-QPEINEKMRSILIDWLVDVHRKFELMPETLYLTIN 188  thale cress
PNR48423      253 EEPVPNIDEHDVGNQLAVVDYIEDIYSFYRKSEVQSCVPPDYMsrQSDINEKMRAILIDWLIEVHLKFKLMPETLFLTTN 332  Physcomitrell...
Q9LDM4        157 EEPVIDIDACDKNNPLAAVEYIHDMHTFYKNFEKLSCVPPNYMdnQQDLNERMRGILIDWLIEVHYKFELMEETLYLTIN 236  thale cress
Q39067        162 KPKIIDIDESDKDNHLAAVEYVDDMYSFYKEVEKESQPKMYMHi-QTEMNEKMRAILIDWLLEVHIKFELNLETLYLTVN 240  thale cress
Q39069        139 ASKTLDIDYVDKENDLAAVEYVEDMYIFYKEVVNESKPQMYMHt-QPEIDEKMRSILIDWLVEVHVKFDLSPETLYLTVN 217  thale cress
ADE77085      194 EDPLPNIDGGDLDNQLAVVEYVEGIYKFYRRTEHMSCVPDYMPr-QRDINGKMRAILINWLIEVHYRFGLMPETLYLTIN 272  Sitka spruce
GBF88540      119 GSPLPDIDASDRGNPLAACDYVNDVYGFYRRVEPQFRVPADYMsqQADINEKMRAILIDWLVEVHLKFKLMPETLFLAVA 198  Raphidocelis ...
PSC72466      968 VPALPDIDSVDAADPLAATDFVTDIFSYYKRVEPQLRIAPDYMsrQTDINDKMRAILIDWLVDVHLKFKLMPETLYLTVN 1047 Micractinium ...

Feature 1                                 ##  #####  ###                #  ##  ##  ##
Q39068        231 LIDRFLSKqnVMRKKLQLVGLVALLLACKYEEVSvPVVEDLVLISDkAYTRNDVLEMEKTMLSTLQF 297  thale cress
XP_002965711  174 IIDRYLSLqqVSRKYLQLVGVTSMLIAAKYEEVWaPVVGDFVFISDdAYTDDQLLSMEKKMLNTLRF 240  Selaginella moellendorffii
O48790        189 LVDRFLSLtmVHRRELQLLGLGAMLIACKYEEIWaPEVNDFVCISDnAYNRKQVLAMEKSILGQVEW 255  thale cress
PNR48423      333 LIDRYLCIqsVSRKNLQLVGVTAMLLAAKYEEIWaPEVNDFVHISDnAYSREEVLTMEKNMLNTLKF 399  Physcomitrella patens
Q9LDM4        237 VIDRFLAVhqIVRKKLQLVGVTALLLACKYEEVSvPVVDDLILISDkAYSRREVLDMEKLMANTLQF 303  thale cress
Q39067        241 IIDRFLSVkaVPKRELQLVGISALLIASKYEEIWpPQVNDLVYVTDnAYSSRQILVMEKAILGNLEW 307  thale cress
Q39069        218 IIDRFLSLktVPRRELQLVGVSALLIASKYEEIWpPQVNDLVYVTDnSYNSRQILVMEKTILGNLEW 284  thale cress
ADE77085      273 LLDRYLSIqrVSRNNFQLVGTTAMLLASKYEEIWaPKVDEFLDILEnNYERKHVLVMEKEMLNKLKF 339  Sitka spruce
GBF88540      199 LIDRYLSVaqVVRKNLQLVGVTAMLIAAKYEEIWaPEVRDFVYISDkAYDRGQILAMERAMLAALDY 265  Raphidocelis subcapitata
PSC72466     1048 LIDRFLEQkqVTRKHLQLVGVTAMLIASKYEEIWaPEVRDFVYISDrAYTRDQILNMEKIMLNTLRF 1114 Micractinium conductrix

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