2PK9,4KRC


Conserved Protein Domain Family
CYCLIN_ScPCL7-like

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cd20558: CYCLIN_ScPCL7-like 
Click on image for an interactive view with Cn3D
cyclin box found in Saccharomyces cerevisiae PHO85 cyclin-7 (ScPCL7) and similar proteins
ScPCL7, also called PHO85-associated protein 1, is a cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Together with cyclin PCL6, ScPCL7 controls glycogen phosphorylase and glycogen synthase activities in response to nutrient availablility. This family also includes Schizosaccharomyces pombe PHO85 cyclin-like protein Psl1 (SpPsl1) and Arabidopsis thaliana PHO80-like proteins, P-type cyclins (CYCPs). SpPsl1 is the cyclin partner of the CDK pef1 (PHO85 homolog). CYCPs may be involved in cell division, cell differentiation, and the nutritional status of the cell in Arabidopsis thaliana. Members of this family contain one cyclin box. The cyclin box is a protein binding domain.
Statistics
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PSSM-Id: 410261
Aligned: 36 rows
Threshold Bit Score: 95.7031
Created: 15-Apr-2019
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
 
CDK interface
Conserved site includes 24 residues -Click on image for an interactive view with Cn3D
Feature 1:CDK interface [polypeptide binding site]
Evidence:
  • Structure:2PK9; Saccharomyces cerevisiae cyclin Pho80 in complex with cyclin-dependent protein kinase Pho85, contacts at 4A
    View structure with Cn3D

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                            # #                                                          
2PK9_B         73 PNISIFNYFIRLTKFss-lEHCVLMTSLYYIDLLQtvypd--------------------ftlnsLTAHRFLLTATTVAT 131  baker's yeast
4KRC_B         80 PTLSSADFLKRIQDKce-yQPTVYLVATFLIDTLFltrdgnnil-------------qlklnlqeKEVHRMIIAAVRLST 145  Saccharomyces...
XP_001748484  137 LNAPLSVFISQIVNYrl-cSRECTVLALVYGQRLLqryps--------------------lvidsRNVHRIFLIAIMLAS 195  Monosiga brev...
XP_004991222  322 VRQPLPLFLEEFVSTrv-cSRECLPLAYIISTRARanlgv---------------------mfsvLNVHVLIAACLTAAS 379  Salpingoeca r...
XP_004998311   56 VPISLRDYIIRMWRLak-vGTEAVLCIPSYIRALYqthnm---------------------vfsdKLAHRIVATCLLIAM 113  Salpingoeca r...
ODV96819      184 PSLSIVAYLERIFKYge-lSTGVILTASIFLFSVIfninykldyhrestininspakirplpvnkFNIFRIVLTVIRVAL 262  Pachysolen ta...
SGZ50922      267 PPITTEQFLLRIKTYsplvSVSVYIHSAYMIFKLCvlldv--------------------mkvtpLNVYRLILALIRCLT 326  [Candida] int...
XP_022204785  212 PPISIPQYLQRLHRFcp-mSTAVYLATSLYIHRLAveera--------------------mavtrRNAHRLVLAGLRVAM 270  brown plantho...
P53124        306 PTLSSADFLKRIQDKce-yQPTVYLVATFLIDTLFltrdgnnil-------------qlklnlqeKEVHRMIIAAVRLST 371  Saccharomyces...
Q08966        362 PSLSFRDFIDRIQNKcm-fGAVVYLGATYLLQLVFltrdemdgp------------iklkaklqeDQAHRIIISTIRIAT 428  Saccharomyces...
Feature 1         ####### ###              #  ##  ##  #######
2PK9_B        132 KGLCDSFSTNAHYAKVGGVr-CHELNILENDFLKRVNYRIIPR 173  baker's yeast
4KRC_B        146 KLLEDFVHSHEYFSKVCGIs-KRLLTKLEVSLLICVCNTKLMV 187  Saccharomyces cerevisiae S288C
XP_001748484  196 KLIDDRYCRNTYYAAVGGLt-VADLNRLEMEFCFLMGFDLCVS 237  Monosiga brevicollis MX1
XP_004991222  380 KLMDDRYCYNTYYAGPARTs-IEHFNECERFICFNLCFDLHAS 421  Salpingoeca rosetta
XP_004998311  114 KMCNDVLYTNRRYSKIAGLs-AGTMLLLELEMLKLLEKNACLP 155  Salpingoeca rosetta
ODV96819      263 KLIEDKNFKQSYYCKITGLesNSDLFKLELNLLFLTDFNLFIN 305  Pachysolen tannophilus NRRL Y-2460
SGZ50922      327 KKLEDIHLKQKNFAVVGGVa-LKDLCKIEVSFLYLLNFKLVVS 368  [Candida] intermedia
XP_022204785  271 KXXEDRSYPHAKVARVGGVs-ESELTRLEISFCFLAGFDLVVG 312  brown planthopper
P53124        372 KLLEDFVHSHEYFSKVCGIs-KRLLTKLEVSLLICVCNTKLMV 413  Saccharomyces cerevisiae S288C
Q08966        429 KLLEDFVHSQNYICKVFGIs-KRLLTKLEISFMASVNFDGLMI 470  Saccharomyces cerevisiae S288C

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