1KXU,1JKW


Conserved Protein Domain Family
CYCLIN_CCNH_rpt2

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cd20525: CYCLIN_CCNH_rpt2 
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second cyclin box found in cyclin-H (CCNH) and similar proteins
CCNH, also called MO15-associated protein, p34, or p37, is normally associated with the cyclin-dependent kinase cdk7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CCNH contains two cyclin boxes. This model corresponds to the second one. The cyclin box is a protein binding domain.
Statistics
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PSSM-Id: 410229
Aligned: 53 rows
Threshold Bit Score: 66.1622
Created: 15-Apr-2019
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1KXU_A       171 HNPYRPFEGFLIDLKTRypil---------------------------------enpEILRKTADDFLNRIALTDa-yLL 216 human
XP_005708164 153 YHPYLSFSAIWSLLEEChwnmear---------------------------ndlvdkKKLYSYARSLIHTSLLTDl-mFF 204 Galdieria sulph...
CCI44847     214 YHPFRPLLGFVDDLRLYakakgkq---------------------------lplellQILHTKASVVVNEFLLTDv-pLL 265 Albugo candida
VEU37687      28 FHPYKAVLAITEDLRTYlksekgrslvtfl---------------dgtdrpiigqdlKPMHDDAQSIVNDVIVSDi-pLL 91  Pseudo-nitzschi...
KJE93582     151 FHPMRSLRGFFYDVRARgavsq-------------------------------taelEAAYRDAKALIDQSFMTDa-cFL 198 Capsaspora owcz...
XP_016209506 195 RHPYRALKGIVLEGHQLvhicqghkapagwtrmseddirdrllkdgsvspkeferrvLSTYEKAKEYLSTKALISdayFH 274 Verruconis gall...
KXN72391     178 LKADRALFGLYLDIQAVgidl--------------------------------imleRTIYAEAQQCWNVVQFTDl-pLK 224 Conidiobolus co...
XP_004335911 172 HLPYNPLHGFIIDLKEStspp---------------------------------aspEKLQGRARRHINDLLITDa-pFL 217 Acanthamoeba ca...
XP_002674344 179 YHPYRSLYAYVHDLHDVg--------------------------------------gDAIYMDAQTKITEIIKMTdaiFL 220 Naegleria grube...
EWM30351     245 YHPYNPFFGLINGLEKVnhvkklg---------------------------ltpdslSRLCTAGQETIDLILPTDl-pLL 296 Nannochloropsis...
1KXU_A       217 YTPSQIALTAILSSASra-------giTMESYLSESLmlken--------rtclsQLLDIMKSMRNLvkkye-------- 273 human
XP_005708164 205 LSPGQIALGIISYAFAhfh-----isfPFELLLSLKSerneeytv---deenwlaLWEQSVNEVKKEmstcggld----- 271 Galdieria sulph...
CCI44847     266 YHPAQLALAALFEAIDpt-------ntDTSQVCREDLiacirlha--pggdsivkSMVDILGSIAKHrkrtlpstdg--t 334 Albugo candida
VEU37687      92 YTPGQIGLAALIVANEnqkgkdnvpqiDLMGYLSHRFeqgadi-------prmssLLQEIGTKLQELkegqhgc------ 158 Pseudo-nitzschi...
KJE93582     199 APPSQLALAALCIACAnh-------giDLTSYISANLqaadk--------peqttQLTESLERAKTLiqmka-------- 255 Capsaspora owcz...
XP_016209506 275 YSPSQIAFASWSCHDPd----------FVNDLLDVKLsgvvp--------arekhKIMDAIAACATMlketq-------- 328 Verruconis gall...
KXN72391     225 FPPSILALFCFQEAFAksd-----qttFFNKYLRHIFkadye---------akseRYNKQCAEIKEDyetrlalplldgs 290 Conidiobolus co...
XP_004335911 218 YPPAQLALAALRKASEee-------gyPLAEYMHSRFhtna-----------gydQLRLNVEAIQKYimegg-------- 271 Acanthamoeba ca...
XP_002674344 221 FSPSVVALGSLYMTHPd----------ITKNFISKMFkeq-------------evQLMNQINQLCEMaatp--------- 268 Naegleria grube...
EWM30351     297 HAPARIALAVLVTCAAecd-----lmePVAEYLSYCFeeedeydtimkevalirpAVEAAQEEVPKSpterk-------- 363 Nannochloropsis...
1KXU_A       274 ----pprsEEVAVLKQKLERCHSA 293 human
XP_005708164 272 -twnisteTEARQLLKKLSFCRDP 294 Galdieria sulphuraria
CCI44847     335 ndqadfdpKAIKAIYKKLKPFHEV 358 Albugo candida
VEU37687     159 -anykvdmQKLKAIHKKLKKCRIW 181 Pseudo-nitzschia multistriata
KJE93582     256 ---teidsSKLKRVDKKLKKCRNP 276 Capsaspora owczarzaki ATCC 30864
XP_016209506 329 ---vpkedNDLKKMNRKMLKCNKI 349 Verruconis gallopava
KXN72391     291 srysrdiaSQVTKLIKKYENPAIN 314 Conidiobolus coronatus NRRL 28638
XP_004335911 272 ----qmdvSRVKKIDRKLKKCLNP 291 Acanthamoeba castellanii str. Neff
XP_002674344 269 -----vekSKVKTADKKLKKIRKF 287 Naegleria gruberi strain NEG-M
EWM30351     364 ----esriEVWRAAMTRLKKAARW 383 Nannochloropsis gaditana
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