1KXU,1JKW


Conserved Protein Domain Family
CYCLIN_CCNH_rpt1
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cd20524: CYCLIN_CCNH_rpt1 
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first cyclin box found in cyclin-H (CCNH) and similar proteins
CCNH, also called MO15-associated protein, p34, or p37, is normally associated with the cyclin-dependent kinase cdk7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CCNH contains two cyclin boxes. This model corresponds to the first one. The cyclin box is a protein binding domain.
Links
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Statistics
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PSSM-Id: 410228
Aligned: 60 rows
Threshold Bit Score: 93.8148
Created: 12-Apr-2019
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1KXU_A        13 HNSSQKRHWTFSsEEQLARLRADANRKFRCKAvangkvl----------------------------------pndpvfL 58  human
543985         7 RDSTHYRDWIFT-EEDLSKTRAKVNEKFTNIVrermleelslqn------------------------keaslevlpptL 61  fission yeast
EGU12066      22 HLSSQFRHWRYS-KEQLEQIRKELNEQAVERVrksweeerasreaapsatkaadgstpstssappsqpatppepseieyL 100 Rhodotorula tor...
CCJ30612       5 EHSTQATVWTFT-VEALQAQRTAVTNEACERIqrnfeqeq--------------------------------nnltvsfL 51  Pneumocystis ji...
RKP15322      11 TQHTQHNNWRFS-QEQLLKRRQDNLRASLARLastp----------------------------------------eqeV 49  Piptocephalis c...
RKO98961      85 EQSTQLRHWRFT-AEQIAAIREQANAVAVARIkhavareqalhaaag-----------------ttsplfpaplgdsdyI 146 Caulochytrium p...
XP_023896068  12 RTSTQFRLWSYT-PEGLVALRHDTHDRAIERIrqhggea---------------------------------nghagdyL 57  Quercus suber
PJF18131      76 SRSHHNRHCIYT-REKVAELRHAVNQEAVAGIkallp-------------------------------------adlepP 117 Paramicrosporid...
XP_025365084  31 THTSQYQHYLFPtSSSSSSLRIALTAADEDAG-----------------------------------------------I 63  Jaminaea rosea
XP_005835561  15 EGTTHQRYWIFT-QERLAELRAEANETACADVnewtnklrragseeqqpdvvl-----gpspgkkarteceesgvqvdcI 88  Guillardia thet...

1KXU_A        59 EPHEEMTLCKYYEKRLLEFCSVfkpaMPRSVVGTACMYFKRFYLNns----------------vMEYHPRIIMLTCAFLA 122 human
543985        62 TVEEELELVNYYSFQLNALSSAl--sLPTHIRSTAILFFKRFYLIns----------------vMEYSPKIISFTSLFLA 123 fission yeast
EGU12066     101 TVADEQALVGYYLTQAVALCGAl--kFPEMVLATAITYLKRFYLRnt----------------cMDYHPKNIMLTCVFLA 162 Rhodotorula tor...
CCJ30612      52 SAHEEWILVGYYAMQMEGLSVYf--eFSSQIKATAVAYLKRFYLMhs----------------vMDYHPKPIMLTCLFLA 113 Pneumocystis ji...
RKP15322      50 TLEDQLDLCSFYEGRLVTLARAl--kYSDAVLGTAIAFFRRFYLKhs----------------iLDHSPATLIFPCLYLS 111 Piptocephalis c...
RKO98961     147 TAEEQTVLCRYFEIMIGQFRHIl--kFDVTLQATAVAFFRRFYLFhs----------------vMEYDPKTVVLNCTYLA 208 Caulochytrium p...
XP_023896068  58 TVDEELRLVQRYCEQIRTTSDHf--qFSGQLKATAVQYMKRFYTSns----------------cMTYPPKEIYKTVLYIA 119 Quercus suber
PJF18131     118 TAAEESALLQFYRLKIPELCRYf--kFPPSVAATAHWLLTRLTLRhs----------------wLTHDPKHTMLCCVWLA 179 Paramicrosporid...
XP_025365084  64 NSASALLLQQYYLLRLPLLSKAf--gLSEKVLATSMTYFKRFWLQrgvaepldgsgsgggnklrAAKGVKVVMLICLYLA 141 Jaminaea rosea
XP_005835561  89 TLQEEQIIQDYYLEGVFSLSNKl--kLPANVETTAITFYKRFYLYcs----------------aMDYHPKDIMFTVLWVA 150 Guillardia thet...

1KXU_A       123 CKVDEf-------------------nVSSPQFVGNLrespl---------gqekaLEQILEYELLLIQQLNFHL 168 human
543985       124 TKCNDh-------------------yISIEQFCKNMpk---------------ttPEEVLEYEFNVCQSLKWDL 163 fission yeast
EGU12066     163 TKTENf-------------------pTSIDTFAARVkt----------------pPADILSLEFLVSQSLHFEY 201 Rhodotorula toruloide...
CCJ30612     114 TKACDh-------------------yISLDQFVRSIpk---------------vtSSLILEHEFLVCRALSWDF 153 Pneumocystis jirovecii
RKP15322     112 LKAEDn-------------------fIPMDQFVTKVkks-------------lsdGEAILAMEFCLSSSLGFQF 153 Piptocephalis cylindr...
RKO98961     209 LKVEDk-------------------yMALKDFCRNIkna--------------pdPEVLLDMETKVIQGLQYEL 249 Caulochytrium protost...
XP_023896068 120 SKVEHg-------------------hMKVAEFGRRIat----------------dAIVIQAPEYKIMQALRFTL 158 Quercus suber
PJF18131     180 TKCENl-------------------hLGMSDFAGKIpn---------------tnVEWLGEMEFVLLAALEYQI 219 Paramicrosporidium sa...
XP_025365084 142 TKTHSt-------------------pISLAAFAMRIsgavggsgseeaaaaiketEQSIRDYEFEVATVLSWRF 196 Jaminaea rosea
XP_005835561 151 CKVEHypsryinaqkvvlnensrefsFDAPAFADHGni----------------pIEHLLRLEQVLLQVLKYHL 208 Guillardia theta CCMP...
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