2W96,3G33


Conserved Protein Domain Family
CYCLIN_CCND_rpt2
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cd20516: CYCLIN_CCND_rpt2 
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second cyclin box found in cyclin-D (CCND) family
The CCND family includes three mitogen-induced D-type cyclins, CCND1, CCND2 and CCND3, which function as regulatory subunits of the cyclin-dependent kinases CDK4 and CDK6, that drive progression through the G1 phase of the cell cycle. Members in this family contain two cyclin boxes. This model corresponds to the second one. The cyclin box is a protein binding domain.
Links
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Statistics
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PSSM-Id: 410220
Aligned: 35 rows
Threshold Bit Score: 71.4883
Created: 12-Apr-2019
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2W96_A       156 TPHDFIEHFLSKMpeae-enkQIIRKHAQTFVALCATDVKFisnPPSMVAAGSVVAAVQGLnlrspnnflsyyrLTRFLS 234 human
XP_018016967 170 TALDFVDSLLRRLavt---gdNIVRRHALTFVALAATESDFvgtKPSLIATAAIVSAVRGIyphl------gkpAMEILS 240 Hyalella azteca
NP_001243936 166 TAFDFVEPFLARVpwg--rsnSLIRTHALTLTSVCYTETEFllvPPSMVAGACITAAARGLrv---------rmSVNELC 234 domestic silkworm
OXA53077     190 IPTDFIQMFEAILpssw-fedKVMHQQVSAYLSLCATDCSFmlhTPSTIAVASLSVAISHLiske-----vgeeVLERFH 263 Folsomia candida
AGH55857     136 APNDYFEYLSHQFnlcqhaqaAEIKKHFYALTALCSTDFKFslyPPSTIALSCLLTALSNLkav-------eidLHNLLN 208 Brachionus manj...
RZF43718     157 TGYDVMDHMIHRLpws--rddVALRSHSLSMIAFCCIELDWmrcKPSLLASASLVAGASGLklaa------tsdLISRVC 228 small brown pla...
KHJ43809     156 TAHTFIQHYLFRLrlpe-steRRLRPQLRLMVALAATEYRFavlPQSMIAASCLCSAYVNVhphpg----saesLARRLD 230 pig whipworm
XP_023341184 171 TPFSFLEFILQQPffascplmDKIRRHSEYLLIIATSEYQFlsiSPSLLATSAVLTAFSGLvqys-----rkpsLVAVLS 245 Eurytemora affinis
XP_023327090 170 TSLDFLQIFIQRYnc-----sEPVFSSAATFLSLAATEYQFysvKPSLMAGAAFLTALQRAddnnt---cgienLHSSLS 241 Eurytemora affinis
XP_023341182 187 TVQSFLQHFSSNLd-------SKVGRHAEILSAAATTEYKYlllRPSLVAAASLSAVCRAAs-----------lHYNIPT 248 Eurytemora affinis

2W96_A       235 RVIkc---dPDCLRACQEQIEALLE 256 human
XP_018016967 241 QCLrt---dMNEVKYVLDTLERTVD 262 Hyalella azteca
NP_001243936 235 ALTrtpaaaAELVARHVERVLARET 259 domestic silkworm
OXA53077     264 QLThi---dKDVIRSVMEKIQIKLA 285 Folsomia candida
AGH55857     209 QFAhi---dYERIRLLREQIEAAFL 230 Brachionus manjavacas
RZF43718     229 HLSgs---dPDQVHWIVMQLERMIA 250 small brown planthopper
KHJ43809     231 QLTti--dsETILMNTRELLAFIWE 253 pig whipworm
XP_023341184 246 HLVgr---pEKEINFVKLAIERLIE 267 Eurytemora affinis
XP_023327090 242 SLItt---eKNGLLLLSSSLNSRVF 263 Eurytemora affinis
XP_023341182 249 ALLk----dEEQIRFIEDHLLSLLL 269 Eurytemora affinis
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