Conserved Protein Domain Family
CYCLIN_AtCycA-like_rpt2

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cd20506: CYCLIN_AtCycA-like_rpt2 
second cyclin box found in Arabidopsis thaliana A-type cyclins (CycAs) and similar proteins
Plant A-type cyclins (CycAs) correspond to a group of G2/mitotic-specific cyclins that are functionally linked to S- and M-phases of the mitotic cycle, which predicts their involvement also in meiosis. CycAs associate with their partner cyclin-dependent kinases (CDKs) to trigger the kinase activity. They contain two cyclin boxes. This model corresponds to the second one. The cyclin box is a protein binding domain.
Statistics
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PSSM-Id: 410210
Aligned: 24 rows
Threshold Bit Score: 161.262
Created: 9-Jul-2019
Updated: 25-Oct-2021
Structure
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Aligned Rows:
 
putative CDK
Feature 1:putative CDK interface [polypeptide binding site]
Evidence:
  • Comment:CDK = cyclin-dependent kinase
  • Comment:Based on the structure evidence that Homo sapiens CCNA2 (5IF1) binds CDK2.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           ##  #                                                                        
Q9C6Y3       326 PTTKCFLRRFVRAahgvheaplMQLECMANYIAELSLLEYTML-SHSPSLVAASAIFLAKYIldptrrpWNSTLQHYTQY 404 thale cress
XP_003055968 217 PTTKTFLRRCLSAae-----sdVKVDFLAGFLSELALLEYTFL-RYSQSTIAAASVSLALMTlgr--spWSKTLEHYTHM 288 Micromonas pusi...
PSC76235     264 PTIKTFLRRYIKAasge-ipldVTFEFLCSYLAELTLMDYPML-NYLPSTIAASCVTVALWMlnk--psWTPTLTHYSGY 339 Micractinium co...
GBG61580     534 PTVMTFLWHFLRAak-----adKRMERTAEHIACLSMLDDGLL-ASPPSLIAAAVVFLASHTlmr--epWSKSMTDWSGY 605 Chara braunii
NP_001353271 335 PTINSFLPRFIKAaq-----anSKTEHLTQYLAELTLQEYDFI-KYAPSMIAASAVCLANHTlnn--eeWTPTMAHYTDY 406 purple sea urchin
XP_002598359 197 PTINCFQKRFLQAak-----vnSKTESLAMYLAELTLQEGETFlKYVPSTIAAASLCLAQHTlnm--qpWTPTLMHYSGY 269 Florida lancelet
XP_002738046 317 PTINVFLDRFLRAae-----adSKAECMARFLAELTLQEYEPYiRYSQSTIAASAVCLANHTlhpnqqpWTATLEHYTSF 391 Saccoglossus ko...
XP_002125998 297 PTSNQFLKRYLKSag-----adKKTEFLAQFLCELALVEFDCT-QYLPSMIAASSVCLASYTvsg--kiWDETMEHYMQY 368 vase tunicate
P51986       296 PTCRDFLSRYLFAana---kpeSQLKYLAEYLSELTLINCDISvKYAPSMIAASSICVANHMlns--ipWTPTLEFYSGY 370 green hydra
XP_004334388 360 ATAKVFLRRYLKAag-----adLTLAFLASYLCEISLLEYNFL-QYLPSMVAAASVFLSLRTler--epWTPTLDFYTSY 431 Acanthamoeba ca...
Feature 1                                                
Q9C6Y3       405 Ka--MELRGCVKDLQRLCsta--hgSTLPAVREKYSQHKY 440 thale cress
XP_003055968 289 Fp--CDLRECVQALHTCHlaa--qqSSLSAVREKYSQMKF 324 Micromonas pusilla CCMP1545
PSC76235     340 Ap--RDLRHCAQAVHQLFvqa--ktSSLPAARDKYASPKF 375 Micractinium conductrix
GBG61580     606 Sa--SDLRQCVERLHAAQmdkevrtGILTAIWDKYSAADH 643 Chara braunii
NP_001353271 407 Ql--GDIYPCVQDLHQLFika--ptMEQQAVREKYKSQKY 442 purple sea urchin
XP_002598359 270 Tl--ADLLPCVQDMHRSFqaa--psSQQQAVREKYRSPKY 305 Florida lancelet
XP_002738046 392 Tf--QDILPCVRDLHHTFvns--vnNQQQAVREKYKTQKL 427 Saccoglossus kowalevskii
XP_002125998 369 Ql--QDLAPCIKRLHEILaga--skNSLQALFEKYKDAKY 404 vase tunicate
P51986       371 Ni--QDLRSCLNEIHLLHlaa--stNPQQAIQQKYKSPKF 406 green hydra
XP_004334388 432 RlqdPTFQQCVRDLHQLQina--pkCNLQAIHEKYAHQRF 469 Acanthamoeba castellanii str. Neff

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