Conserved Protein Domain Family
Tudor_SpSPF30-like

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cd20446: Tudor_SpSPF30-like 
Tudor domain found in Schizosaccharomyces pombe splicing factor spf30 (SpSPF30) and similar proteins
SpSPF30, also called survival of motor neuron-related-splicing factor 30, is necessary for spliceosome assembly. It contains one Tudor domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Statistics
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PSSM-Id: 410517
Aligned: 6 rows
Threshold Bit Score: 76.7586
Created: 24-Nov-2006
Updated: 25-Oct-2021
Structure
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Aligned Rows:
 
putative
Feature 1:putative peptide binding site [polypeptide binding site]
Evidence:
  • Comment:based on the structures of other Tudor-like family proteins with bound methylated/dimethylated peptides
  • Comment:In general, the Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                  #       #                   #  # #            
O94519        77 FTPGNLVMARWvsgDYLFYPSRITAvsgfgaNKKYTVQFLDYPDIETVslKHIKAM 132 fission yeast
BAE57127     102 FSVNEHVLARWtsgDNSFYPARITSitgsssNPVYLVSFKSYGTVESLtaKDLRPI 157 Aspergillus oryzae RIB40
XP_018225143  74 YKTGETVMARWvsgDNAFYPAKITSvtgsstNTVYTVKFLEYNTIETLqaYHVKPI 129 Pneumocystis carinii B80
ODQ69251     148 FKTGAVVLARWlsgDKQYHRAKIAGitgssiQPMYTVKFFDYASTDTVplSCVRPV 203 Lipomyces starkeyi NRRL Y-11557
XP_009018607 734 MKPGDVCMSKWk--DGKFYRAQIISc-----SPIMLVNYLDYGEVDQVy-GGIMPL 781 Helobdella robusta
ODV88618      62 YGAGEFVLARWk--DGKYYKSEILSqtgsseNPIYTIKYLDYDEIDTVgvRDLRPL 115 Tortispora caseinolytica NRRL Y-17796

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