Conserved Protein Domain Family
Tudor_TDRD15_rpt5
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cd20440: Tudor_TDRD15_rpt5 
fifth Tudor domain found in Tudor domain-containing protein 15 (TDRD15) and similar proteins
TDRD15 is an uncharacterized Tudor domain-containing protein that contains seven Tudor domains. This model corresponds to the fifth one. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Links
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Statistics
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PSSM-Id: 410511
Aligned: 6 rows
Threshold Bit Score: 225.413
Created: 11-Dec-2018
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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putative
Feature 1:putative peptide binding site [polypeptide binding site]
Evidence:
  • Comment:based on the structures of other Tudor-like family proteins with bound methylated/dimethylated peptides
  • Comment:In general, the Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                           #      #      
B5MCY1        956 YSSFNIQIGSEEEVYISHIySPQKFYCQLgRNNKDLEMIETKITEsvnlqnfpkyDSNKMRVCISKYveDGLSYRALAIP 1035 human
OCT81294      927 YSDFNIKVGVLEQVYITHIySTGKFYCQLaRNTEAIEALMKKVSEigeqi-sqldCTRENKLCIVKYyeDGNFYRALAHP 1005 African clawe...
EMP26150      978 YSSFNIKIGSEEEVYITHIySPAKFYCQLnRNTEIVDKLMKKIAEisnipnsseyDPSKTRLCIAKYfeDGLFYRALASS 1057 Green sea turtle
NP_001182210  940 YSSFNISCGSEELVHVTYVcSPWEIYFQLdRNTEILNRLTERVAEesqlf-tsisDNCSSKVCLAKYfcDGSWYRALVHP 1018 zebrafish
XP_007895290 1001 YSSHGIKPGSEEKVFVTHVvSLAKFYCQLdKNTAVLDKLMIKINNiskmmhgqnlDMDKTSMCLAKYfeDGQWYRALVHS 1080 elephant shark
XP_006000043 1063 YCSFNIKVGSEEEVYITHVcSPSEFYCQLgRNAENTNALMEKIGQfvkltqdqilEVEQLRLCLAKYfgDGQWYRAMAYP 1142 coelacanth

Feature 1                   #  # #                               
B5MCY1       1036 tdsssEFQVYFVDFGNKQLVgENMLRAISAqfpeLLFTPMQAIKCFL 1082 human
OCT81294     1006 iesssLFSAFFVDFGNSQMVtKKELLPIPDtavdLLCKPMQAIQFYL 1052 African clawed frog
EMP26150     1058 vgsssYLLAYFVDFGNKQMVvRDKLMPIPDhatdLLLTPMQAIKCYL 1104 Green sea turtle
NP_001182210 1019 vqsnqHVSVVFVDYGNKEIAeKTNVMAIPTtavdVLLTPMQALRCSL 1065 zebrafish
XP_007895290 1081 vkspfHLKVFFIDYGNMQIVdKNDVLPIPEeasdLILIPMQAVKCCL 1127 elephant shark
XP_006000043 1143 lespfHLKVYFVDYGDTQIVeKKEVLPIPQqateILSVPMQAIKCCL 1189 coelacanth

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