Conserved Protein Domain Family
Tudor_TDRD15_rpt3

?
cd20438: Tudor_TDRD15_rpt3 
third Tudor domain found in Tudor domain-containing protein 15 (TDRD15) and similar proteins
TDRD15 is an uncharacterized Tudor domain-containing protein that contains seven Tudor domains. This model corresponds to the third one. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Statistics
?
PSSM-Id: 410509
Aligned: 5 rows
Threshold Bit Score: 283.211
Created: 11-Dec-2018
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
 
putative
Feature 1:putative peptide binding site [polypeptide binding site]
Evidence:
  • Comment:based on the structures of other Tudor-like family proteins with bound methylated/dimethylated peptides
  • Comment:In general, the Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                         #      #        
B5MCY1        478 MEIEAAYIAFIAYVLNPSNFWVRTndhrnEFQEIMKNINKFYDLCENDEmILRKPEPGLFCCARYsKDRRFYRAVITEIN 557  human
XP_006000043  572 MKSDAIYVAYAEYVLNPSNFWIRTdefnsDFEAMMKNIADIYNKTGVSEeLLNKPKPGLLCCARYsRDLHYYRAVITEVF 651  coelacanth
XP_007895290  505 MTVDGSYLGFVEYVINPSDFWIRTleyncEFECLMKNITDHYSRIGINEeLIQAPEPDLFCCARYyKDQHYYRAVITEVL 584  elephant shark
POI19876      372 MQMNSHHAAFVVYVINPSNFWIQPcayqnEFQALTENIADVYNQCGAEErVLKNPEPGLLCCARYsRDGHYYRGIVTEVL 451  Chinese bambo...
OCT81294      468 MDVDSVHVGYVEYVLNPSNFWIRTdelqnEFSAMMEKIAEIYNPCGPTErVIKDPEPGDLCCALYnKDRHYYRAVVTDIF 547  African clawe...
Feature 1                #  # #                                                
B5MCY1        558 GyKINVYFLDYGNTDSIPFFDVKILLPEFceLPALAMCCSLAHIFPVEDLWTKAAIDYFKK 618  human
XP_006000043  652 DlHVSVYFLDFGNTDTVPLCDVKNLLPQFmeLPALAMHCSLAHVTPIDEVWTKNVNDFFRK 712  coelacanth
XP_007895290  585 GdEVRVCFIDFGNSEIVDTSDVKCLLPEYskLPALAMNCSLAHVFPIEEVWTKNATDYFKK 645  elephant shark
POI19876      452 DvNVTVYFLDFGNTDVVPSYDVKTLLPEFsdLPALAMCCELACTFPVDEVWVKEENDFFKK 512  Chinese bamboo-partridge
OCT81294      548 DlKVSVYFPDFGNTETVPFYDVKTLLPEFevLPALAMCCSLAYAYPLEDVWVKHANDFFKQ 608  African clawed frog

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap