Conserved Protein Domain Family

cd20405: Tudor_Agenet_AtDUF_rpt1_3 
first and third Tudor-like Agenet domains found in a family of Arabidopsis thaliana DUF724 domain-containing proteins (AtDUFs)
The family includes a group of AtDUFs (AtDUF1-3 and AtDUF6-8) that may be involved in the polar growth of plant cells via transportation of RNAs. Members of this family have four Tudor-like Agenet domains, except for AtDUF8, which contains only two copies of the Tudor-like Agenet domain. AtDUF4 and AtDUF5 are not included here due to the lack of a Tudor-like Agenet domain. The model corresponds to the first and third Tudor-like Agenet domains in AtDUF1-3 and AtDUF6-7, as well as the first Tudor-like Agenet domain in AtDUF8. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
PSSM-Id: 410476
Aligned: 34 rows
Threshold Bit Score: 51.1048
Created: 30-May-2019
Updated: 25-Oct-2021
Aligned Rows:
peptide binding
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:peptide binding site [polypeptide binding site]
  • Structure:6IE4; Arabidopsis thaliana Agenet domain-containing protein in complex with H3k9me1 peptide, contacts at 4A
    View structure with Cn3D

Sequence Alignment
Format: Row Display: Color Bits: Type Selection:
Feature 1                              #                     # ##          # #                
6IE4_A         14 LKPGSAVEISSdei-gfRGSWYMGKVITipsssdkdsvKCQVEYTTLFFDKeg-tKPLKEVVDm----SQLRPPAP 83   thale cress
GAX78544       16 LTIGMHVEILGeee-gyAGSFSTAIVTEite-----sgRVTVEFDEFLEEDg--vTKLKETFDfs-siFRIRPALP 82   Chlamydomonas eus...
PNW78611       14 LPLNSVIEVSGddeegfKGSWSRAALVAdg------lfTVKVQFTEFVDDKg---LALVEVVAr----ARIRPAPP 76   Chlamydomonas rei...
KZN09259      148 ISRGTEVEVTFeg--enYNVWHLGSVLQveg-----ndRFLVKYRCLGLENk--aEFRTEVIDs----RCIRPAPP 210  Daucus carota sub...
Q9FZD9        154 FSPGTMVEVFSa----kEAVWSPAMVVKetdv--ddkkKFIVKDCNRYLSC----NGDEARPTnivnsRRVRPIPP 219  thale cress
XP_018474036  187 YSPGEKVEMTRrir-kmEDIWVTTMAIKqiee--dgkrKIIIKRLSESLRLsdddEDDALFKKvd--iCKLRPCPP 257  radish
O22897        150 FSSGTMAEVSTivd-kaEVAWFPAMIIKeiev--dgekKFIVKDCNKHLSFsgdeARTNSTIDs----SRVRPTPP 218  thale cress
Q9ZVT1        150 FSPGTLVEVSCvid-kvEVSWVTAMIVKeiee--sgekKFIVKVCNKHLSCrvdeAKPNMTVDs----CCVRPRPP 218  thale cress
F4I8W1        152 FSCGTMVELRF------DCAWIPVIVIKele----kdkRFLVKYWNKSYSCr---ESKNLIVDs----LRLRPMQP 210  thale cress
F4KEA4          2 FSPGTMVEVSSkin-egEVVWVPSMVIKefke--ddeyKYIVKDKSFSCEGk--kARPNKTVDl----SSLRPIPV 68   thale cress

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