Conserved Protein Domain Family
Tudor_BAHCC1-like
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cd20397: Tudor_BAHCC1-like 
Tudor domain found in the BAH and coiled-coil domain-containing protein 1 (BAHCC1) family
The family of BAHCC1 includes BAHCC1 and trinucleotide repeat-containing gene 18 protein (TNRC18). BAHCC1 may function as a transcriptional regulator. The biological function of TNRC18 remains unclear. Members of this family contain one Tudor domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Links
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Statistics
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PSSM-Id: 410468
Aligned: 12 rows
Threshold Bit Score: 98.1702
Created: 29-May-2019
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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putative
Feature 1:putative peptide binding site [polypeptide binding site]
Evidence:
  • Comment:based on the structures of other Tudor domain superfamily members with bound methylated/dimethylated peptides
  • Comment:In general, the Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                       #      # #                                # # #                 
O15417       2220 STRFLPQGTRIAAYWSQQY-RCLYPGTVVRGlld-----------ledDGDLITVEFDDGDTGRIPLSHIRLLPPDYK 2285 human
Q9P281       1971 SSRYLPPGTRVCAYWSQKS-RCLYPGNVVRGasgd----------edeDLDSVVVEFDDGDTGHIAVSNVRLLPPDFK 2037 human
XP_023345491 1286 RAEKLPVGTRVCAYWSSKY-QFMHPGTVVPHepgs----------tkhHAKFVNIELDDGDSRELNLEYVRLLPHNYP 1352 Eurytemora affinis
XP_023345491 1073 DFVYTQPGTRICTYWSSQL-QYLYPGTVISI-----------------QNDLVHVELDDGDEREVPLDSIRLLPPSYP 1132 Eurytemora affinis
THD27192      996 SVRHVPPGTRVCAAWSEQLaVDLYPGTVAHAepk-----------ediQPNSVPVGFDDGDRRQVPISSIRILPDHFT 1062 liver fluke
XP_018667493  350 DEHEVPPGTRVAAYWTVKM-HSLYAGSVTSGk---------------hERGEVYIDFDDGDLSKIPIEQIRLLPPDYT 411  vase tunicate
XP_023348495  962 WSGDLPAGSRVCTYWSSAY-SCLFPATVSPTqe-------------nsQKGQILVELDDGDSRLVDISRIRMLPQDYS 1025 Eurytemora affinis
CDS31056      161 SPDQLVPGTRVCAIWSATLgNVYFPGRITDFtpln---------snnkDEITFPIQFDDGDSALVPFKDILLLPNDYK 229  Hymenolepis mic...
VDO91976      312 SLAEVPTGSRICALRNRQM-IGFAPGTVRSDgdrhrvl---skrgsesISPKISIKFDDGDTGKIGLCDVRLLPADFR 385  Soboliphyme bat...
Q3LHL9       1178 SVESVPVGTRLCAYWSQQY-RCLYPGRAIDSeqvvdgtassatnaattAPDFVSVEFDDGDSGRIRLQNIRMLLSDYP 1254 fruit fly
XP_015924998 1249 VTSNLPEGTRVCAYWSQQY-RCLYPGVIGKApcps----------adwSEPRVFVQFDDGDSGQIPIKNVRLIPPDII 1315 common house sp...
KXJ13611     2325 AVEYLPVGTRVCAHWSPQY-RCFYPGNVIETppd-----------eksEVGKLWVEFDDGDSGIFPLSDLRKIITECP 2390 Exaiptasia pallida

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