Conserved Protein Domain Family
PWWP_HULK
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cd20147: PWWP_HULK 
PWWP domain found in Arabidopsis thaliana protein HUA2-LIKE (HULK) family
The HULK family includes HUA2-like proteins 1-3 (HULK1-3), which are probable transcription factors that act with partial redundancy with each other. They may play diverse and essential roles in the control of plant development, physiology and flowering time. The PWWP domain specifically recognizes DNA and histone methylated lysines.
Links
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Statistics
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PSSM-Id: 438975
Aligned: 6 rows
Threshold Bit Score: 143.014
Created: 23-Jan-2019
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Feature 1:putative methyl-histone binding site [polypeptide binding site]
Evidence:
  • Comment:the aromatic residues form the three-walled methyl-lysine cage that directly participate in histone methylated lysine binding and recognition.
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                   #  #                      #                                           
Q9LEY4         21 GDLVLAKVKGFPAWPAKIGQPEDWNqapdpKKHFVQFYGt-gEIGFVTppDIQPFTSETkkklsar-----cqgktvKYF 94   thale cress
F4IZM8         25 GDLVLAKVKGFPAWPAVVDEPEKWGhsadsKKVTVHFFGt-qQIAFCNhgDVESFTEEKkqsllt------rrhakgSDF 97   thale cress
EFJ15369       21 GDLVLAKVKGFPAWPAQVSRAEDFGrqrnpAKVFVVFFGt-kQIRFCQhsEISAFTVEAraalhar----tlskcvpSDL 95   Selaginella m...
XP_024388385   33 GDLVLAKVKGWPAWPAQIGKLETQGkh--aGKYYVTYFGpgqQIGWCLpvELSEFDADQreasiqk----slkktadKKF 106  Physcomitrell...
F4IN78         25 GDLVLAKVKGFPAWPAVVSEPEKWDaspdsKKVFVHFFGt-qQIAFCNpgDVEAFTEERkqsllt------rrhakgSDF 97   thale cress
GAQ86358        6 GTLVLHKLKGFPEWPAMVSSCKAKKsasipGYVFVKYLGl-pERFWAPvaELDEITGDIlsslkerarsktikkkwrVKF 84   Klebsormidium...

Feature 1                          
Q9LEY4         95 SQAVEEISAAFEESQKQ 111  thale cress
F4IZM8         98 VRAVKEITESYEKLKQQ 114  thale cress
EFJ15369       96 KRAVKEICEVADESGEL 112  Selaginella moellendorffii
XP_024388385  107 ISAVKEICALQDERVGD 123  Physcomitrella patens
F4IN78         98 VRAVKEIIESYEKLKQQ 114  thale cress
GAQ86358       85 SNAVRELEKLWAERKGG 101  Klebsormidium nitens

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