Conserved Protein Domain Family
PBP1_ABC_HAAT-like

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cd19986: PBP1_ABC_HAAT-like 
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides
This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Statistics
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PSSM-Id: 380641
Aligned: 26 rows
Threshold Bit Score: 339.217
Created: 19-Jul-2018
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic Leu/Ile/Val-binding protein with bound valine

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                     
SDI44458   38 KIGMVAdltgksalTGEFKKRGAQIALdeingaggvdgkkIELVVEDDrgt-ndGTVSAFQKLISDpdIVAIIGpitstn 116 Paenibacillus naph...
CCY00389   61 RIGLTTvltgdrslEGEYASNAAKIITeeintqggvlgrpIEIVIEDAlgt-dvGAVNAYRKLASDdsIVAIVGpdssnd 139 Clostridium boltea...
CUP31709   64 RIGIVTtlsganagHGEYCKEGAELWKedvnarggilgrpVELVYEDNget-eqTYMNAMVKALSDddLCAVYSngysnq 142 Anaerotruncus coli...
KLN56085   30 LIGVSLpqtgpkalVGRNFKQGVELAVseinasggvlgkpLEVVFEDDqgdnpnGAINAVNKLMQVnkVPVMIGphysvt 109 Variovorax paradoxus
AMJ61533   34 VIGAAApltgpralLGRNYKQGVELALeeinaaggvlgkpLQITFEDDqgdnpnAALNAVTKLMQVskAPVILGphfsva 113 Bosea sp. PAMC 26642
SBW10978   49 YIGLTDafsgeraiNGEYTKEGVELFLseinaaggvlgreVVVVYEDDqgt-eaSATNAYQKLISDndVSAVVLnkyssl 127 uncultured Clostri...
KYZ75990   37 RIGVVSsltgeralHGQYTRNGIQLAVeeinaqggingrkLEAVFEDDngn-daGAVNAFNKLSGSn-VAVAIGpifstm 114 Anaerosporomusa su...
SAL78988   33 KVGMMTestgpsseAGIYQANGAKLALeetnkaggvlgkqLELRNEDNqst-npGSVLAISKLTSSgdVAALIAtvrstq 111 Burkholderia sp. L...
KUK39493   37 DVGFPVemsgdaaiTGDLQRKGTEMALekinaeggingvpMRFIYEDTkgt-npGAISAFNKLLFShnVIMSFAtvrstm 115 Synergistales bact...
SFV74029   31 LIGMNTpvtgaaagEAVYFMKAAKLAEkhana----agynIKLLIQDNqst-npGALAALNKSIEQdhIFALLGpikstq 105 Desulfovibrio piger
Feature 1                       ##                                                            
SDI44458  117 alsineitkkTGIPVMIGGTnvnltt--elknqWFFRFRPSDaYSAKTIVDFSTdkl-gkkKVAIVYDTDafGTAGKDML 193 Paenibacillus naph...
CCY00389  140 gmaqspsaleFKILTTAQGSsptlknmcnndnpYLFQLRACDdTLCAALIKYSVeel-gikSYAVMHDTEtsSADQARLF 218 Clostridium boltea...
CUP31709  143 itlvlpevanYEIPLLAGNSsqacl---danndYYWMLRLSDaNVSPAMVLACRdql-gmkKPAILNVNDsyGRGMADFV 218 Anaerotruncus coli...
KLN56085  110 qm-atqktycNGKVVSITGGtsvait--hsgcnYVVRTRSDDdVQARALIAYARnelkageKTAVFYANDdfGKSGQARV 186 Variovorax paradoxus
AMJ61533  114 qlatqktyctGATVSITGATgipvt---angckFVVRIRGNDnIQARALVEYARkel-ktdKIGIIAINDdmGRGGLSRI 189 Bosea sp. PAMC 26642
SBW10978  128 vlaveqfvaeAEIPAICSGSsvkle---aldneYMLSTRRSDsGSGLTIAAYCEklg--atKVAILHANDalGTGMAPVV 202 uncultured Clostri...
KYZ75990  115 nlamspgikkAEIPTLVIGSsndig---nqknpWMFQARTNDaISATAIAKYAAnql-klkKIAIMHDTDnfASGAAAVA 190 Anaerosporomusa su...
SAL78988  112 iqaisptvmrAKLPILVGGTdtslt---hvnnpWIFRARPNDsYSARVIADYGVntl-klkKWAIIHSTDafGNGGKNAL 187 Burkholderia sp. L...
KUK39493  116 vhalapiikeNEVPAIFGGSawsls---elevpWMFRVRTDDrTVAQIMAKFMVedl-ghkKIAGLHDSDafGTGGFVET 191 Synergistales bact...
SFV74029  106 vlaisdrvkqTELPTLIGGTnvnlt---qqgnpWFFRCRPDDsIVVKVMLKYIKedm-gltKIAVLHDADafGTGGADLI 181 Desulfovibrio piger
Feature 1                                                                                     
SDI44458  194 VAEYknkg-itpvLIEGYtantkdfTPVLENIRKsgadVINGFmtasadVAQLVVQMRQLgiqAEFVSSaagaqtttlkl 272 Paenibacillus naph...
CCY00389  219 TEALksyg-iepvVTVPFttgtkdfSSHIAQVQAsgadAIIGAafq-teAAILIQQIRSLgieAPILGSngfadpvtiql 296 Clostridium boltea...
CUP31709  219 VKAIeeng-melaIQVECtaeekqfTPILTQIVNsgadGIIAInhq-dqAALVMMQIEAMdiqLPLMGCsqyasalamdt 296 Anaerotruncus coli...
KLN56085  187 VAQMaalg-lkpvAVESHnpsdkdySAQLAKLQKsgaeLVILWahd-tdAALILRQARQFglpFKFAGAvlsedaflk-l 263 Variovorax paradoxus
AMJ61533  190 TAVLeaag-lkpvAVESHnagdkdfSAQLAKLKNagaaLVLMWthd-neAGLIVRQARQLgleMKFGGStsaseptfikl 267 Bosea sp. PAMC 26642
SBW10978  203 ASALagyg-ievvSTQQFatdeknfAPYIAKIIDsgcdMLVSIaqt-neAPLIMRAVKDAgldIPCIGSsasaqsstlqn 280 uncultured Clostri...
KYZ75990  191 KKALedln-lppvLIVAYnsgdkdfTPQLAKIKAsgadGILAWsqq-teAGLIMKQKKALdlnIPLIGSnsyvtkiaidl 268 Anaerosporomusa su...
SAL78988  188 TDALktag-vtpvMTQGFtsnsqdfTPIVLAIKNsdvdIVSTYiasstdVAIFAKQLRQLgvkATIIGSpsvstdtamkl 266 Burkholderia sp. L...
KUK39493  192 AKALkemygidvlTEQKYstgtkdyTAQLLAIKNsgatCVFAWgtrledDAIILRQKAQLgleVDFVGSasysstpirdi 271 Synergistales bact...
SFV74029  182 DALApkag-ltvvKREKYttkdkdyTAQLLAFRVagaeVMIHYgtnaedVAVCQRQYRQLglpYAYIGSpssavkdtihl 260 Desulfovibrio piger
Feature 1                                                                                     
SDI44458  273 agdklngIYGVNDfaldqseetkrfv-enfkqkytdvpdlFSGWVYDALHVLAkvmaekgtspdqiregil--------- 342 Paenibacillus naph...
CCY00389  297 agelndnVYCASAwvpntpnpkgaalaekykelygddcgkAAAQIYDHISVICeaitlagstdreavream--------- 367 Clostridium boltea...
CUP31709  297 ageasngWYSLADwsnevqtesgkafveayrkaynrdsdmQSVCAYDAMLLLEdaitragtddpkavneal--------- 367 Anaerotruncus coli...
KLN56085  264 agsaaegSMSASYfvptdpnpavqafvkkyearykmapdvWSATYYDATILAArainearsadvekiraaf--------- 334 Variovorax paradoxus
AMJ61533  268 agaasegVVSANDfvasnpaphvqafvkkyeakygslpeiWAATYYDAAHYAArainaagstdphkvraaf--------- 338 Bosea sp. PAMC 26642
SBW10978  281 avgasegWYSVTAfsptisegkaaewiakyekmfgrapdmTSATTYDALSMICwaieeagstdpkaintal--------- 351 uncultured Clostri...
KYZ75990  269 akenaedVYSVADyvtstpipkgqefakkykekykidsefNAAMTYDALYLAAealkkagstekeavkkam--------- 339 Anaerosporomusa su...
SAL78988  267 agnalhgSYSIADfspgaspeaqaya-dkykaaykvdpdfYSAWAYDSMKLLAlaignakstkpddiskal--------- 336 Burkholderia sp. L...
KUK39493  272 agdsvngIYSAAGftvanddplvqeyvkefqakygelpdeNSAWTYSSTLMLAdalrkanviqvvdgkpmmlptkearea 351 Synergistales bact...
SFV74029  261 agkaaegILAIADatpggspeytays-eaykkeygeemdaWAAWNYDALMILAraiheagpdrskvreail--------- 330 Desulfovibrio piger
Feature 1                                        
SDI44458  343 ------avkghkgvegeynfdpnGDGLh-sYTVVQ 370 Paenibacillus naphthalenovorans
CCY00389  368 ------ntigdyqgaitkydcrtNGDCgrgGLLVK 396 Clostridium bolteae CAG:59
CUP31709  368 -----kqtkdvvgamtsytylegDHSLgtsIMLTQ 397 Anaerotruncus colihominis
KLN56085  335 ------sslnysglladykcdkaGDCNk-qVNIVE 362 Variovorax paradoxus
AMJ61533  339 ------dkvkydgvlatyacqenGDCNq-qINIVE 366 Bosea sp. PAMC 26642
SBW10978  352 -----hsikdfegissvftyqgtPMLSt-aEYVSQ 380 uncultured Clostridiales bacterium
KYZ75990  340 -----ssikdfvgvsttftfdenNRGGt-gVWIVQ 368 Anaerosporomusa subterraneum
SAL78988  337 -----haikdykgvegtytfdsnGDGLh-gYNVVR 365 Burkholderia sp. LMG 22936
KUK39493  352 irqalkgvrdfktpmgsytcdkwNNMLh-eMPIIQ 385 Synergistales bacterium 54_24
SFV74029  331 ------nlrdyrgvlgtysfspnGDGRh-sACVVE 358 Desulfovibrio piger

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