4KV7


Conserved Protein Domain Family
PBP1_ABC_ligand_binding-like

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cd19978: PBP1_ABC_ligand_binding-like 
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periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions
This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Statistics
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PSSM-Id: 380633
Aligned: 77 rows
Threshold Bit Score: 301.416
Created: 18-Jul-2018
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
ligand binding
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:ligand binding site [chemical binding site]
Evidence:
  • Structure:4KV7; Rhodopirellula baltica possible leucine/isoleucine/valine-binding protein binds formic acid, contacts at 4A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                   ###
4KV7_A      18 LKFGXSTALSGpaaeLGINXRHGILAAFDEAKakn-hlPSKTLKLIALDDgyepARTAPNXHRLTDehEVLAVVGNVGTP 96   Rhodopirellula b...
KKQ49663    32 ITLGQSACFSGalgiYGNIIKNAITARINRINkqg-giHGYKVALVSLNDnsdpQRTYDNTKKLRTq-NIDMFIGNMGTR 109  candidate divisi...
SBS39685    37 PELGSSMPFTGlngsMGKEVKIGISIGLQRYQn----qQHIPFKIIYKDDtydpKKTAKNIRKMIEkdHIIGMINNVGTP 112  Marinomonas spar...
KKQ48485    36 VLLNASLPLAGelslIGNQIFDGLTLFFNKVRqed-lqGKYVINLSALDDqgsgSRTKNNAKKLQS--RAPLFTSFFGAN 112  candidate divisi...
KKP25293   413 IVIGSTMDFDAgvqdQTMGVSKGLFLVINQINrqg-glKGKYIKMVLLNDqelpLKAKKNVENLIKnyKTDILIGPTATP 491  candidate divisi...
OJW53342   753 VRIGLTIDLSRaariAGERIQAGIDLRLRKANreg-giNGAFLRLFIADDkyspAFTLQNVQEFIYkyDATIILSPLGTS 831  Alphaproteobacte...
OQR41469    29 ILIASSMPQSSglkaWGDAVFITTNSYFNYANdnn-liKDKKIVLKVLDDkyepDLTYENITKLSKd-DILAFYGIVGTP 106  Arcobacter cryae...
KKP95992   393 FIFGSYLDLSGsiknIGEDLKRGLSLRFNKENieyggiNGRFLRLVALDDrynqTLTLDALIKLKNdfKTNLLVNGLGTR 472  candidate divisi...
SBT21011    28 IRLGFTGPLSGpsalLGHQLVNGIELGLKRLNtn--keLPFTVSLITKDDgyepSRTVPIIEKMVEddNIVGLISSVGTP 105  Marinomonas sp. ...
ETI60855    25 LRFGFTGPLTGqnafLGNEAVRGIRLGFERINnr--geLNYRVSFFPLDDqyepSKTVPQVEKLIEnvGVKALIGSIGTP 102  Marinomonas sp. ...
Feature 1                          #                       #                              #    
4KV7_A      97 TaiTAIPIAQQTKTPFFGAFTGAsalrkt---esvefVINYRASYAEETAAXVDALVakgi-kpeEIGFFTQNDsYGDDG 172  Rhodopirellula b...
KKQ49663   110 SiiKLLPLIQEKKIAMFFPWSGDplldd----pslshIINGQGLLGPQLTTIAHHVTttl--rmdKIALFHADDgFSTAA 183  candidate divisi...
SBS39685   113 TavVSAKIAQQEKILLYAPISGSnflrppaedpsfryLINYRSSYEEEVTRIFNALMaatpfseqDLVLFSQDNtIGSGG 192  Marinomonas spar...
KKQ48485   113 SmhAVAKLIKQKKIAMFFPIESAsdyrq----qafdnIIFFRPPINKELDALIQYCIqql---krKIAIFYEASsWGEEG 185  candidate divisi...
KKP25293   492 TleAYLDKVEKKEVLVLFPITGTisfrt----nkypyIIHFRDSYTNEAKALMEYAYkvl--dakKYAFFHESGaFGLNA 565  candidate divisi...
OJW53342   832 TtkALLPLVRDKKILLLFPHSGAnmfrd----pelqnIINYRPTYADEARALVRYAKevl--fkqRFAFFYQDDnFGYDP 905  Alphaproteobacte...
OQR41469   107 TnkRVLPILEDSGMVYFSPFSGAqflrd----knlknIINFRPSYKQELENLLNYIVdek--kldKIAIFYQNDeYGEEG 180  Arcobacter cryae...
KKP95992   473 PlqTAMDFASKENMKILFPYTGAsigrq----enlknIVNLRASYADEAEALVDYGVntl--rknRFVIFYQDDaYGRAG 546  candidate divisi...
SBT21011   106 TivAAIPTLVELQLPLISPFTGSsmlrsr---gvsslIFTHRASYQKEVASLAKVVAkefniapsDIAIFAQKDsYGEIT 182  Marinomonas sp. ...
ETI60855   103 TnlATLDTLAKHDIPLITPLSGAkslrae---raapfIFNVRASYTDEVYFLINTLTkiynirpdEIAIFAQKDsYGDAG 179  Marinomonas sp. ...
Feature 1                                                                                      
4KV7_A     173 FFGGLAAIRRHqsvkVSSLPHGRYrrntsqVEDGLADLLXHqplpkAVIXVGTyepCSKLIRXARXNnf--nPQFLAVSf 250  Rhodopirellula b...
KKQ49663   184 AETLIKILSEHh---QAPIAVASYnrftldIVSPAKTLINAdp--rVVICIATsmpTVKLINHFFAAgh-ygTTFCGVDs 257  candidate divisi...
SBS39685   193 ANWIDNLLLQHfndtNPHYLKVSYdrdaavVENAVADLLLVtptpkYIFLIASgkpAAKFVRLVRQYgl--dPVFIGVSf 270  Marinomonas spar...
KKQ48485   186 LQHIKKTLEKNd--aITLVAHGSYqprtvnIASAVHTIVKSdp--dAIICIAQarpAYNFIRQVVNKgl-hkTLFLGLSe 260  candidate divisi...
KKP25293   566 FKGAEEVLNKYk---ITNYVKAAYvrnttnFSDAIKKITDFsp--dTIILLSSgiaTSGFIQQIGVNhl-vqKVILGLSd 639  candidate divisi...
OJW53342   906 LNAAKEILLNEydisREEICEASYvrntilVDKAVKKITLFnp--eVIFFFSTydaSRALIEKIGIQkl-snVTLMGISf 982  Alphaproteobacte...
OQR41469   181 YISTLEILKNKn---IKLLSTGTYkrntlsINHAFNEIKKSkp--eVIVMIGAykaNSLFIKKAKNDeilknVIFCNISf 255  Arcobacter cryae...
KKP95992   547 RDPAKKLLVEKy--kITDILEVSHsvgslqLDKAAEEIIKFgp--sAILFFSIevvSAELIEKIGIKsl-mnVALLAVSf 621  candidate divisi...
SBT21011   183 VRSLIKALESYglehSSDILRVGYtrnnpsTEEAAAKILTHtpqpkVIFLISTypaAADLITSLDENgv--sPLYAALSf 260  Marinomonas sp. ...
ETI60855   180 LSSAMQALSQAglkdPTSVLQIRHtrnnteVDHVVADILGVfpipkAIIMVSTyetTSNIIERLAQFgi--hPLYATLSl 257  Marinomonas sp. ...
Feature 1                                                                                      
4KV7_A     251 vgada-------lqrslGDLANGIVATQVVPHFdsd-lpLVREYRDAXRDYdpe--------lplSFVSLEGYIVGRILV 314  Rhodopirellula b...
KKQ49663   258 tlft---------plltKDRGVDYFYTSAVPHPnqttiaLAQNYKADMKLYfpn--------ehiNTLSFSYYVSAAIVL 320  candidate divisi...
SBS39685   271 vgtst-------fanslKDVDARVFITRVVPPLeqtdlpIVQEFLADKKKFlatlpknkqdtftaSALMFESYISTRILI 343  Marinomonas spar...
KKQ48485   261 lisl--------qstlkKSRGLTVITSSVTPNPststlpIVEEYRNDMKKFfpn--------kplLPFSLEGYINAMLFY 324  candidate divisi...
KKP25293   640 sdqey-------ikdyvNRKGINFVVAKIMPSFnnlklpIVKEFRDLADANdf----------alDNFLLEGFIGGSIML 702  candidate divisi...
OJW53342   983 itdlfrdyasgisdpeqPGKGLSVVLSRVVPDFrdqdieIVREYHTEMQREyph--------irlDVGSLESYINVSILL 1054 Alphaproteobacte...
OQR41469   256 gdansi----vkeleatNTDTKNLIFSQIVPNYndkslkIVQEYQEIMKKYsne--------sslGFISFEAFLASKVLV 323  Arcobacter cryae...
KKP95992   622 mshs--------fteflKTRGLSSVLSQVLPNShgd-tpIAQECRDTLKMYmps--------vdiNADLFEGYVSASLLV 684  candidate divisi...
SBT21011   261 vshda-------lntriKHTEAKILSTQLHPCHndvsdpLIKDFLADFEQYgna--------etpTSATLEGYIAVRQVE 325  Marinomonas sp. ...
ETI60855   258 sglea-------islrtKNTSSNIIISKTVPPLtqsdspLVKQFLEDMAKSgdt--------lppTTIQFESYINALVVG 322  Marinomonas sp. ...
Feature 1                                                            
4KV7_A     315 KAVTsikgeisrssi-aaaleqlgqfdIGLGAPLTLgp-nDHQASs-KVWPVLI 365  Rhodopirellula baltica SH 1
KKQ49663   321 QAMQesqnphhkeei--ikiietmdntSIEGLPITFnpknRHAFGs-DISIITR 371  candidate division TM6 bacterium GW2011_GW...
SBS39685   344 KALEkepyidqynli--daleklgefdLGLGSPLRLda-tHHQASh-SIWLTYL 393  Marinomonas spartinae
KKQ48485   325 AALNytpapqspqal--iktlesfnsfNFKGLDLTYnt-tTRSLSs-KVWINTG 374  candidate division TM6 bacterium GW2011_GW...
KKP25293   703 DAFKqidgeitkekv--ysvisnfknyYLKGLILTYnp-qTNELTkdNVWLEEM 753  candidate division TM6 bacterium GW2011_GW...
OJW53342  1055 DTLKridppytheki--ihemeniqmrNFKGLLLDFdp-kTRSLSk-TVLLDSG 1104 Alphaproteobacteria bacterium 41-28
OQR41469   324 NQISkieelgelnrknllnalksppknILYELELDFk---NNQLLn-KTYLFEY 373  Arcobacter cryaerophilus
KKP95992   685 EAIKiigsdvtsekl--lryfeslknvNFKGLKLNFns-eTRQLMh-NVWLDVG 734  candidate division TM6 bacterium GW2011_GW...
SBT21011   326 NVLLhvspnraptraeflsylkqyqqlHKDTEKKVVenssPSQIEl-PIWLDLK 378  Marinomonas sp. Cmf 17.2
ETI60855   323 QALLtlkdiptsqai--qtslkqlaedNKYNQSDPVlq-fLNQNKq-RIWIQLI 372  Marinomonas sp. D104

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