4YLE,5DTE


Conserved Protein Domain Family
PBP1_ABC_sugar_binding-like

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cd19970: PBP1_ABC_sugar_binding-like 
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monosaccharide ABC transporter substrate-binding protein
Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.
Statistics
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PSSM-Id: 380625
Aligned: 20 rows
Threshold Bit Score: 349.626
Created: 26-Jun-2018
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
ligand binding
Conserved site includes 12 residues -Click on image for an interactive view with Cn3D
Feature 1:ligand binding site [chemical binding site]
Evidence:
  • Structure:4YLE; Burkholderia multivorans sugar-binding protein binds alpha-D-erythrofuranose, contacts 4A
  • Structure:5DTE; Actinobacillus succinogenes periplasmic sugar-binding protein binds D-allose, contacts at 4A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           #   # ##                                                                  
4YLE_A     34 KVALVXKslaNEFFLTXENGAKEYQkhnasQFDLITNGikdETDTANQIRIVEQXIVsKVDAIVLApadsKALVPVVKKA 113 Burkholderia multi...
PCK03563   29 KVALIMKslaNEFFVNMAESAKSHHsknpeIYDLIVNGiknESDLAQQVALVDQMIAmGVNAIVICpadsKALVPALARA 108 Alteromonadaceae b...
SLM27674   42 KVALVMKalsNPFFAKMEKGAKDYAhk--nGIHLEVFGverETDVQEQITIVKRLIQqKYPAIVIApadsKRLVPVVREA 119 Candidatus Desulfa...
NP_744602  34 KVALVMKslaNEFFRTMEDGAKDYQkthadEFELIANGiknETDTGEQIRIVEQMVNaGAKALVIApadsKALVSAVKKA 113 Pseudomonas putida...
ADK80397   36 TVALVMKslaNEFFLTMEQGARDHHmnnaeRYDLLIYGikdEQAVSQQIHIVEQLMAiDVDAIIIApadsKALVPVCQRA 115 Sediminispirochaet...
SKA75792   33 KVALVMKslaNEFFSNMAEGAKKHQaahaaDYELLVSGiknETDLSEQVNLVEQMVAqGARALIIApadsKALVPSLKRA 112 Prosthecobacter de...
NP_866998  90 RVALIMKslaNEFFSTMAKGAEAHQaeyseQYELVVNGikdERDVSRQVALVEEMVAsGVDAIVIApadsKVLVPALRRA 169 Pirellula sp. 1
GAT62168    7 VIGLVMKslqAEFFQEMQKGALAFAat-rnDFELITVGtntQTEIELQIELIDNLIQqKVDALVVVpidsKALVPAVVKA 85  Porphyromonadaceae...
KUM24893   34 KVGLVMKslaNEFFKQMQAGAEEYAaknkdKFDFAAVGmkdERDFAAQVDAIENFITqNYNIIVVApadsKAMVTPIAKA 113 Mesorhizobium loti
OZG41022   27 TVGMVLKsvrNEFFIEMAKGAETYAtthpdALTLQLEGiqqEVDVTGQEAIIRKMIGqKVDALVVVptdsVAMLPVLMEA 106 Aeromonas sp. A35_P
Feature 1               #                                                      #   #          
4YLE_A    114 VDaGIIVVNIDNRLDpdvlksknlnvpFVGPDNrkGARKVGDYLAkkl-kagDQVGIVEGvstttNAQQRTAGFQDAxka 192 Burkholderia multi...
PCK03563  109 VNaGITVVNIDNRLDaqvlaefglnipFIGPSNrdGAKKVGDFVLkny-pigTEVAILEGiptayNSIERRIGFELAaee 187 Alteromonadaceae b...
SLM27674  120 VDkNIVIINIDNALDkntlgeagikvpFVGSDNflGSRMTGDYVRskl-pkgGNVLYIEGirgneNADLRRDGFLAGiss 198 Candidatus Desulfa...
NP_744602 114 MDqGVVVINIDNRLDpdllkskgisvpFVGPDNrkGARLVGDYLAsqklkagDQVGIIEGvstttNAQQRTAGFKDAmda 193 Pseudomonas putida...
ADK80397  116 MAsGVAIVNIDNKFDatviaerglhvpFVGPDNyqGAKAAGDYLAdhl-ssgNQVAIIEGipsayNSQQRCLGFRKAmdd 194 Sediminispirochaet...
SKA75792  113 QQaGVLVINIDNKLDadvlkqaglnvpFVGPDNreGAKKVGDVLAkkl-kagDEVAIIEGvttafNGQQRRAGFEDAmka 191 Prosthecobacter de...
NP_866998 170 IEaGVIVVNIDNRLDadvlqqenvavpFVGPDNmaGAKAVGDYLAanr--kgEKVAILEGirtsfNAQQRLKGFEAAmke 247 Pirellula sp. 1
GAT62168   86 VKaGIKVINIDIRLDddlltqngieltYVGPDNatAAKAVGDVLAaki-gkgAKVILIEGlavaeNAQQRKAGFLQSiee 164 Porphyromonadaceae...
KUM24893  114 LKaGIKVINIDVALDedakkkagidlaFFGPDNraGAKLAGDALGkal-gkgGKVVILEGnpeadNAKQRKLGFDDAvke 192 Mesorhizobium loti
OZG41022  107 IRaGILVINMDNKLDdralvlegvnipFVGPSNfvGARSVGEYVSkkl-pagSKVGLIEGppgaiNSRARSDGFRAAlra 185 Aeromonas sp. A35_P
Feature 1                 #                          #                         ##             
4YLE_A    193 ggxkvVSVQSGEWeiDKGNAVASAXLNeyp-nlkALLCGNDnxAIGAVSAVRAAgkq-gkVYVVGYDninaikpxlkdgR 270 Burkholderia multi...
PCK03563  188 agakvVALQSAQWdqTKAAQITSAILSqnp-ninVIFAANDnmALGAASAINMAqld-heIALAGFDnisairpllqngS 265 Alteromonadaceae b...
SLM27674  199 apfkiLGTISANWhaDEAMNQVADFLSrtkesvdVIACANDvmALGALQAINAFmegekrPLVTGYDnipevrselfngN 278 Candidatus Desulfa...
NP_744602 194 aqmkiVSVQSGNWeiDKGNAVAASMLNeyp-dlkALLAGNDsmALGAVSAVRAAgkt-gqVQVVGYDninaikpmledgR 271 Pseudomonas putida...
ADK80397  195 agimiVDTRPALWemDRAYTTVISILNehr-nvrALLCANDnmALGAAAAVKAAskr-nsMYIIGFDnisavnnelkkgD 272 Sediminispirochaet...
SKA75792  192 agmniVATQSGQWemEKANTVAAGILSahp-hvkALLCANDnmALGAAAAVQSAgks-gqVLIVGFDnisaikplledgR 269 Prosthecobacter de...
NP_866998 248 anmeiVSSQSADWemSRANTVASSMLSehp-eitAILAANDsmALGAIAAVKSAgra-geVQIVGFDnitairqaieegK 325 Pirellula sp. 1
GAT62168  165 nklqlVASEAADWetDKAEEVFARLYAqhp-didGVMCSNDamALGVIKVLDKSdka-gkIAVVGFDndpsvqpllengQ 242 Porphyromonadaceae...
KUM24893  193 hgldlLDSKTAHWetEEANTLMTNFLTqhp-diqGVMAANDsmALGVVKAIDAAgks-gqIKVVGFDnipavgpllkegK 270 Mesorhizobium loti
OZG41022  186 admvvAGVRSGYWdiAQGKSATIDLLKatp-dvnALLCSNDnmAIGAAQALAELglk-gkVLIGGYDnipgihpylndgS 263 Aeromonas sp. A35_P
Feature 1           #                                    
4YLE_A    271 VLATADQYaAKQAVFGIDTALkaiaehrkqaelsGVVETpVDL 313 Burkholderia multivorans ATCC 17616
PCK03563  266 IMATAEQYgDKFAVFGIEFAVkvldg----epgsGDRQTpVDI 304 Alteromonadaceae bacterium
SLM27674  279 IQATIEQHpEMMGAYGLKLAVqslkg----etvpVYEPTpLDL 317 Candidatus Desulfamplus magnetomortis
NP_744602 272 VLATLDQAaSQQAVYGIQAALkmvkgekpdvdadNVIQTpVEL 314 Pseudomonas putida KT2440
ADK80397  273 ILATVDQHaALIAVNGIEMALsmlng----edvdLICTTpVEL 311 Sediminispirochaeta smaragdinae DSM 11293
SKA75792  270 VIATADQHaDQLAVYGIEAALkvlqg----genpADQTTaVDV 308 Prosthecobacter debontii
NP_866998 326 VLATADQHgDKLAVFGIEAALeqlgessdeeasiEDVETpVDL 368 Pirellula sp. 1
GAT62168  243 MQATIDAFgSQMAVEGIQYTLkvvgg----lenrGSFTTpFTL 281 Porphyromonadaceae bacterium NM7
KUM24893  271 MLATVEQYgAQMAAMGIDYGLrelag----ekfsGWVKTdVKL 309 Mesorhizobium loti
OZG41022  264 VVATADQYpGKQAQYALDLALkaltqkitqadlpGIVQTpVEL 306 Aeromonas sp. A35_P

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