3S99


Conserved Protein Domain Family
PBP1_BMP-like

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cd19963: PBP1_BMP-like 
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periplasmic binding component of a basic membrane lipoprotein (BMP) from Brucella abortus and its close homologs in other bacteria
Periplasmic binding component of a family of basic membrane lipoproteins from Borrelia and various putative lipoproteins from other bacteria. These outer membrane proteins include Med, a cell-surface localized protein regulating the competence transcription factor gene comK in Bacillus subtilis, and PnrA, a periplasmic purine nucleoside binding protein of an ATP-binding cassette (ABC) transport system in Treponema pallidum. All contain the type 1 periplasmic sugar-binding protein-like fold.
Statistics
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PSSM-Id: 380618
Aligned: 115 rows
Threshold Bit Score: 255.89
Created: 14-Dec-2017
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
ligand binding
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1:ligand binding site [chemical binding site]
Evidence:
  • Structure:3S99: Brucella abortus basic membrane protein binds adenine, contacts at 4.0A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           ##       #                                                                
3S99_A     28 KVGFIYIGppgdfgWTYQHDQARKELVeal-gdKVETTFLENvaegADAERSIKRIARa-GNKLIFTTsfgymdPTVKVA 105 Brucella melitensi...
YP_144567  23 KACFIYVGpvgdagWTYAHDVGRKKAEaa--lpWLETRYVESvp-eAQVVPVIDRFVRe-GCRVIFATsfgymdGVLEAA 98  Thermus thermophil...
OQY32202   43 KAGFVYIGpagdfgWTYAHEQGRLYVEeq--fpWLETITVESvp-eGDAVRFIDRMVQqqKCDIIFTTsfgymdDTVKAA 119 Spirochaetaceae ba...
ACB07774   53 KAAFIYIGpigdygWSHAHHQAKEMIDkk--ydWLETTQVESvt-pAASAGVMEQLISq-GYNVIFTTsfdfmdPTLEEA 128 Candidatus Korarch...
KPL21956   22 KACFIYVGpigdygWSHAHNEARLFVEnq--faWLETAYAEAvp-eADVERFLDRFIVeeGCDVVFTTsfgfmdGTIAAA 98  Anaerolineae bacte...
OGR57775   40 KAGFIYVGpvgdygWSNAHEQARRALQkk--fpWLESVIVESvp-eADSSRIIDRLVSeqKCDIVFTTsfgymdATLAAG 116 Elusimicrobia bact...
EAU69756   27 KACFIYVGpvgdigWSYAHDEARKLALke--lpWLETQYVESvp-eGQALPVIDRLVKg-GCKAVFTTsfgfmdQTLEAA 102 Stigmatella aurant...
SFO80871   27 QIGFVYQSpvsdvgWVAVHESARKQLEkef-gnRIKTQVVQDvkagPDGARVIRELVGn-GAGLMVLGsfgymnDGLKAA 104 Variovorax sp. PDC80
AEM39633   85 KAFWVYVGpvgdmgWSYEHDQGRKYVEevlgkkLVETGYVEQvp-eDRVGQVIDDAVAk-GNKLIFTTsfgymdPTNRKA 162 Pyrolobus fumarii 1A
OBQ62656   35 GIVLVVPSpvgdvgWGRALADGLEPVKaay-gdKVKVTILENiqegPDADRIMNKAVAd-GNKVLIAGsfgyqnGALQIA 112 Mesorhizobium loti
Feature 1                #                                              #                     
3S99_A    106 KKfPDVKFEHATGykt-adNMSAYNARFYEGRYVQGVIAAkmskkGIAGYIGSVPvpeVVQGINSFMLGaqsvn-----p 179 Brucella melitensi...
YP_144567  99 KKyPDVIFAHATGikr-apNVATYMADFYQVYYLNGLAAGaltktGKVGYVAAFPipeVKRHINAFALGvravr-----p 172 Thermus thermophil...
OQY32202  120 EKyPDVTFFHCSGfkr-stNMGTYMGDMYQIYYLNGLIAGamtesNKLGYVGAFPipeLFRHMNAYALGakean-----p 193 Spirochaetaceae ba...
ACB07774  129 KKhPDIIFWHCSGykr-saNMGTYFTEFYQAYYLNGLMAGaltktKKIGYVAAHLipeVVRHINAFAIGvnevc-----p 202 Candidatus Korarch...
KPL21956   99 NKyPDKIFFHCSGfkr-tpNSGTYFIDFYQLYYLNGLMAGaltksGKVGYVGAHPipeVVRHIDAFTLGvrevn-----p 172 Anaerolineae bacte...
OGR57775  117 KRhPGKKFMHCSGfkr-daNVGTYFAELYQMYYLNGLMAGalsksGQAGYVAAHPipeVVRHINAFALGmkean-----p 190 Elusimicrobia bact...
EAU69756  103 KKyPEVVFAHATGfkr-apNMATYMADFYQLYYLNGLMAGaltktGKVGYVAAFPipeLKRHISAFALGvravn-----p 176 Stigmatella aurant...
SFO80871  105 AEnPKVNFVHASGfrq-aaNFGTYNARWYEAAYVAGLVAGkvtksNKLGYVGALPipdVVSTINAFALGaqksn-----p 178 Variovorax sp. PDC80
AEM39633  163 GQyPDVLFGHCSGykrlypNVVTYFAEAYQAYYLNGILAGamtktGKVGYVAAHFipeVIRHINAFALGvregaklvgrn 242 Pyrolobus fumarii 1A
OBQ62656  113 RRnPDVTVLHASGfqv-apNFSPFAAQYSQGTYLMGMAAAalsktGKLGSVSAFAipeLITSINAFALGaqavk-----p 186 Mesorhizobium loti
Feature 1                #                                                     #              
3S99_A    180 dfrVKVIWVNSWf---DPGKEADAAKALIDQGVDIITQHt-dSTAAIQVAHDRg-----IKAFGQASDMIKFAp----dT 246 Brucella melitensi...
YP_144567 173 daqVLVRWINAWy---DPAKAREATEALLAQGADVFAFTe-dTPTVIQTAARKg-----AYSFGHYTPMLKFAp----dH 239 Thermus thermophil...
OQY32202  194 eatVSVKWIYAWy---GPDKAREAAEALVSEGCDVLGFTe-dTPTVLEVAQEHqdkgdtVYGLSHYSPMQAYAe----dA 265 Spirochaetaceae ba...
ACB07774  203 dckVYVREIGAWv---DPTKARQAAEALISEGVDVLAFTe-dTPTVVQVAEEHfmrgerVLAFGHYSPMKEYGk----dV 274 Candidatus Korarch...
KPL21956  173 eatVDVRWLFSWy---DPAKAREAAEALIADGADVLAFTe-dSPTVLQVGQEYteqgqpVYTFSHYSPMEEFGp----dS 244 Anaerolineae bacte...
OGR57775  191 kaqVHVKWLYSWy---DPAKAKEAAESLVSEGCDALAFTe-dSPAVIQVAEERmkqgqpVYAFSHYSPMQKFGe----nS 262 Elusimicrobia bact...
EAU69756  177 eatVNLKWINAWv---SPTKAREAAEALMAEGNDVLAFTe-dTATVVQAAGRKk-----VPVFAHYSPMYRFSp----dF 243 Stigmatella aurant...
SFO80871  179 aakVSVVWVNEWf---NPGSERDAANTLMQQGADVIGSGfqdNPAVLQAAEAKg-----VWSIGMFSDHRKSAp----qK 246 Variovorax sp. PDC80
AEM39633  243 pneVKVIVRGPLgawfAPDKARAEAEVLISQGVDVIAFTe-dSTAIVTTIAEYytqgkrVYTFSHYSDMRRILegdarnA 321 Pyrolobus fumarii 1A
OBQ62656  187 dveVSVVWVNSWf---DPAKEQEAAKALLAQKCDAIFSNaqdTPSVVAACEEAg-----IPAFNLNSSMRKYAp----kT 254 Mesorhizobium loti
Feature 1           #                                                                        
3S99_A    247 QLTAVVDEWGPYYIDRAKAVLdgt------------------wksQNIWWGMkEGLVKMAPftnmpDDVKKLAEETEAR 307 Brucella melitensis...
YP_144567 240 VVSGQIVHWDVIYIDFLKKVKegvytp-------------knlenVDYFWLLqHGAVEMGAdygvpINPKHVPLLKAAQ 305 Thermus thermophilu...
OQY32202  266 SLTGQLTDWGVLYEQMLYDYKagkta---------------dctnYDLLWLMkEKAVELGGtwddmINPKYVEVLKSQG 329 Spirochaetaceae bac...
ACB07774  275 CVSGQIAHWEVIYDDILSKIYagsyts-------------enlenVDYWWKLkEGSVELGCaynepVNPKFIDELRSVR 340 Candidatus Korarcha...
KPL21956  245 AVSGQLVDWGIIYQDILMKVYlgvynn-------------qnlenVDYWWLMrEKGAILGGsfehpINPKFEDALKAVE 310 Anaerolineae bacter...
OGR57775  263 VVSGQLVDWGILYEEVLLRVYtgi------------------wdnRDWFWMArEGAALLGGefgapVNPKFIEPLKAKT 323 Elusimicrobia bacte...
EAU69756  244 VVSGQLVHWEKIYIDFLKKVRegayap-------------gklqdVDYWWLLhEGAVELGTqpgmpINPKWVDALKKAQ 309 Stigmatella auranti...
SFO80871  247 LLTSLTHDWTPYLRQAVQDTLdgk------------------fkgTAYAATLaNGGVSLADwnpgvPADVVQMAKQARA 307 Variovorax sp. PDC80
AEM39633  322 VLAGQIVDWGPLYLELVIRAIlarlvnpekpgntdiwsdfppatpRDYWWDMrMGVFDIAPpresrAAYVKKCGRIPDV 400 Pyrolobus fumarii 1A
OBQ62656  255 YLGCVATDWSPFFKASVDAHLagt------------------fkgASAFLGVgEKVVEVVDwnpgiPADTMTKIKEIEA 315 Mesorhizobium loti

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