2N3F,2L2N


Conserved Protein Domain Family
DSRM_AtDRB-like
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cd19878: DSRM_AtDRB-like 
double-stranded RNA binding motif of Arabidopsis thaliana double-stranded RNA-binding proteins (AtDRBs)and similar proteins
This family includes a group of Arabidopsis thaliana double-stranded RNA-binding proteins (AtDRB1-5). They bind double-stranded RNA (dsRNA) and may be involved in RNA-mediated silencing. Members of this family contain two to three double-stranded RNA binding motifs (DSRMs). DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Links
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Statistics
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PSSM-Id: 380707
Aligned: 6 rows
Threshold Bit Score: 98.3577
Created: 2-Nov-2018
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
Download Cn3D
 
putative RNA
Conserved site includes 16 residues -Click on image for an interactive view with Cn3D
Feature 1:putative RNA binding site [nucleic acid binding site]
Evidence:
  • Comment:Based on structure evidence that Homo sapiens TARBP2 (5N8L) binds siRNA.
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1           # ##  ##    ##            ## #                     ####  ##           
2N3F_A        83 YKNLLQEIAQKEssLLPFYATATSgp-shAPTFTSTVEFAG--KVFSGE-EA--KTKKLAEMSAAKVAFMSIK 149  thale cress
2L2N_A        19 FKSRLQEYAQKYklPTPVYEIVKEgp-shKSLFQSTVILDG--VRYNSLpGF--FNRKAAEQSAAEVALRELA 86   thale cress
ELU02009      50 FKNKLQEYCQQKkiAIPKYELIPDp---aNNDKKSAVIVNG--ERFESV-GAy-PKKKESEMDAACVALKALQ 115  Capitella teleta
AGW15601     513 FKNSLQEFAQKKgiPVPRYFSKKA-----QIGMMSTVVISD--HKFHST-GLh-KDKKQSEQNAAWFALKKLG 576  starlet sea anemone
XP_002740205 584 YKNILQEHCQKNrfDTPKYESTKIqdnpaQFTTVLTYKTLGntVKYSSE-GLthSNKKESEQSAAKVACLGLD 655  Saccoglossus kowalevskii
XP_020600878   6 YKSLLQIHCQKAkvQLPQYSCAQRvq-gfSPVFVANLTVLG--RTFTSEaEF--SSKKQAEKNAAKVALRELG 73   Orbicella faveolata

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