Conserved Protein Domain Family
RecA-like_PEX6_r2
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cd19527: RecA-like_PEX6_r2 
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6)
PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Links
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Statistics
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PSSM-Id: 410935
Aligned: 7 rows
Threshold Bit Score: 272.464
Created: 28-Nov-2017
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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putative ATP
Feature 1:putative ATP binding site [chemical binding site]
Evidence:
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                          ########                                       
Q6CPV1        710 VKGEIMDTIDMPLKHPELFSSGMKKrSGILFYGPPGTGKTLLAKAIASnfSLNFFSVKGPELLNMYIGESeanVRRVFQK 789  Kluyveromyces...
Q99LC9        714 VKKEILETIQLPLEHPELLSLGLRR-SGLLLHGPPGTGKTLLAKAVATecSLTFLSVKGPELINMYVGQSeenVREVFAR 792  house mouse
Q7SGP2        999 VKDAITETIQLPLERPELFAKGMKKrSGILFYGPPGTGKTLLAKAIATeySLNFFSVKGPELLNMYIGESeanVRRVFQR 1078 Neurospora cr...
P36966        727 VKKDILDTIETPLKYPHWFSDGVKKrSGILFYGPPGTGKTLLAKAIATtfSLNFFSVKGPELLNMYIGESeanVRRVFQK 806  Yarrowia lipo...
Q54CS8        927 VKSEIMDTIQLPLEHPHLFASGIGKrSGILLFGPPGTGKTLLAKAIATecSLNFLSVKGPELINMYIGESeknIREIFNK 1006 Dictyostelium...
NP_171799     666 VKTSILDTVQLPLLHKDLFSSGLRKrSGVLLYGPPGTGKTLLAKAVATecSLNFLSVKGPELINMYIGESeknVRDIFEK 745  thale cress
NP_001303242  625 VKKEILETIQLPLEHPELLSLGLRR-SGLLLHGPPGTGKTLLAKAVATecSLTFLSVKGPELINMYVGQSeenVREVFAR 703  human

Feature 1                                                                      #                  
Q6CPV1        790 ARDakPCVIFFDELDSVAPKRGnqGDSGGVMDRIVSQLLAELDGMssg---gdgVFVIGATNRPDLLDEALLRPGRFDKM 866  Kluyveromyces...
Q99LC9        793 ARAaaPCIIFFDELDSLAPSRGrsGDSGGVMDRVVSQLLAELDGLhst----qdVFVIGATNRPDLLDPALLRPGRFDKL 868  house mouse
Q7SGP2       1079 ARDarPCVVFFDELDSVAPKRGnqGDSGGVMDRIVSQLLAELDGMsggegggggVFVIGATNRPDLLDPALLRPGRFDKM 1158 Neurospora cr...
P36966        807 ARDakPCVVFFDELDSVAPQRGnqGDSGGVMDRIVSQLLAELDGMstag--gegVFVVGATNRPDLLDEALLRPGRFDKM 884  Yarrowia lipo...
Q54CS8       1007 ARQakPCVIFFDELDSLAPSRGngADSGGVMDRVVSQLLAELDGMqks----sdVFIIGATNRPDLLDSSLMRPGRLDRL 1082 Dictyostelium...
NP_171799     746 ARSarPCVIFFDELDSLAPARGasGDSGGVMDRVVSQMLAEIDGLsds---sqdLFIIGASNRPDLIDPALLRPGRFDKL 822  thale cress
NP_001303242  704 ARAaaPCIIFFDELDSLAPSRGrsGDSGGVMDRVVSQLLAELDGLhst----qdVFVIGATNRPDLLDPALLRPGRFDKL 779  human

Feature 1            
Q6CPV1        867 LYL 869  Kluyveromyces lactis
Q99LC9        869 VFV 871  house mouse
Q7SGP2       1159 LYL 1161 Neurospora crassa OR74A
P36966        885 LYL 887  Yarrowia lipolytica CLIB122
Q54CS8       1083 LYL 1085 Dictyostelium discoideum AX4
NP_171799     823 LYV 825  thale cress
NP_001303242  780 VFV 782  human

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