4DT1,4EQ6


Conserved Protein Domain Family
Csm2

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cd19478: Csm2 
Shu complex subunit Csm2
Csm2, together with Shu1, Shu2, and Psy3, form the Shu complex which is thought to play a role in maintaining genome stability by linking error-free post-replication repair to homologous recombination.
Statistics
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PSSM-Id: 410886
Aligned: 11 rows
Threshold Bit Score: 206.058
Created: 16-May-2012
Updated: 17-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
heterodimer
Conserved site includes 20 residues -Click on image for an interactive view with Cn3D
Feature 1:heterodimer interface [polypeptide binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1         #                                                                              
4DT1_A         7 ELITIWPSPTKNKLCQFIKQNLSKeh------vVTQLFFIDATSSFPLSQFqklvpptlpenvrIYENIRINTCLDLEEL 80  Saccharomyces c...
XP_002494427  27 DLVTAWAAPNPNSLAQYVANTIDKsn------sDVIVFYIDASNTFPLYQFeklvpk-dergakIYESIRIQIALNLSEL 99  Zygosaccharomyc...
XP_001644558   9 PLLTVWGSPSSLEIAKLISTTLNAqie---nntPLQLYYIDATNSFPLTQFqklvpv-nednkrIYDYIRIMTCLDLYEL 84  Vanderwaltozyma...
XP_446749     10 SLLTLWPVAPDIDLAQYIYQFLTSevg---tqtEKEVYFTDSINSFPIHQLqelvn---esnqsIYENIKINTALDLHEL 83  [Candida] glabrata
XP_003680546  10 KLLSIWQSPPQKNLAKFVRQIIGSl-------nNRTLYYIDATNSFPLQEFqkiia---veqkeVYDRIRIITCLDLSEL 79  Torulaspora del...
CCH61426      10 SNLSIWVDPLPIILSNLMISILQEn-------dDIEIQFIDSNNSFPINQFqkiiqn-kdidsrIYERVRISTCLDLNEL 81  Tetrapisispora ...
XP_002555426  11 DKVVLWFDSDEECISKMMATFLTVdsa---eqsAKTLYFIDAMDRFPIKEFcrlvpp--kenaaVYENVRIMASLDMEEL 85  Lachancea therm...
XP_003675112  25 DLITAWVSPKKIDLAKFISSALQDq--------PSQLYFIDATNSFPIREFqretpv--atnkdVYDNIRIITCLELEEL 94  Naumovozyma cas...
CCF60237       7 KNVTIWTTFKNTTVSQLICDFLKEe--------NTILHYIDAVNSFPLMEFqnlvpa-nednkrVYDNIIITTSLNMQEL 77  Kazachstania af...
XP_003684892   9 NLLTAWVPDSTTAVTEFITKALLNsaessapdiFLKLYFIDATNSFPISQFqetipi-cdennhIYENIRITTCLDLNEL 87  Tetrapisispora ...
4EQ6_A         8 ELITIWPSPTKNKLCQFIKQNLSKeh------vVTQLFFIDATSSFPLSQFqklvpptlpenvrIYENIRINTCLDLEEL 81  Saccharomyces c...
Feature 1               #                                                                #       
4DT1_A        81 SAITVKLLQIlsmnkinaqr------------------------------gtedavtepLKIILYINGLEVMFRNSqfks 130 Saccharomyces c...
XP_002494427 100 NLIVRKILQFvsrekvars-------------------------------lnkdteqngLKVLLILSGIEIMFKNSrmss 148 Zygosaccharomyc...
XP_001644558  85 NRITNKMLQLisidkiqkkqnik------------------------hrnkepdslhntYGILVFINGLEVMFRNTqmke 140 Vanderwaltozyma...
XP_446749     84 SSIIKKNTESlilkkiqn---------------------------------kktndlkpFQILSVINGLDVMFRSTlvsf 130 [Candida] glabrata
XP_003680546  80 SKTLNQVVQVlnidkiqqqqr----------------------------rkekdgentnVEILLILNGLEIMFRNTqmec 131 Torulaspora del...
CCH61426      82 KIISDRLVQInnirkirheqkkinrknesnnitkdinnedstkdsndnannsnilnksdTPSFLFISGLDVMFRNTqlgk 161 Tetrapisispora ...
XP_002555426  86 SSVVSQVVSSaqmshstr---------------------------------lrdpsapqPQVCVVIRGLDVIFRNTalkd 132 Lachancea therm...
XP_003675112  95 TILVNKIIQTiqlnkierqkkksq----------------------nnshhndiqffpdLKMRVIINGLEIMFKNTqfkq 152 Naumovozyma cas...
CCF60237      78 YNIVKKIIENt-----------------------------------------------eKIRLIVINGLDIMFRNSsfnd 110 Kazachstania af...
XP_003684892  88 LININKMTQLiainrfkkqqksdn---------------------sakqsikdqqgicrSGILVFINGIEIMFRNSqiks 146 Tetrapisispora ...
4EQ6_A        82 SAITVKLLQIlsmnkinaqr------------------------------gtedavtepLKIILYINGLEVMFRNSqfks 131 Saccharomyces c...
Feature 1             #  ##   #  ##  #                                                        ###
4DT1_A       131 spqrSHELLRDTLLKLRVMGNden---enaSIRTLLEFPKeqlldyylkknnnt---------rtssvrskrrriknGDS 198 Saccharomyces c...
XP_002494427 149 pqepHHMILRDLFLRLRVEANhsnd-qfglTLKTFLIVPLqecqrcqispgtrm----------pnnkrqrmtpmnvGNS 217 Zygosaccharomyc...
XP_001644558 141 sqerTHLFLRDILLRIRAIANqpkd-dnsiELRSIVTFPSnelnkslnkssdn------------pakrpksinlikGNT 207 Vanderwaltozyma...
XP_446749    131 tneqAHLMLRDVMLRLRQVCNeydc--splTFKIILLFNRsdvmellpkqrhsa---------ahqqkkmkynnameGNS 199 [Candida] glabrata
XP_003680546 132 spseSHLLLKDLLLKLRTIANncev--gepMLRTVLTFPKeellkfnssnsqs------------hgnkrlkstitnANT 197 Torulaspora del...
CCH61426     162 saeeAHSLLKECLLKLRIVGNtiid--dqfFLRTIIGFPInelavpesnsnhtfsgs---yksidkignkrvrrslkGNT 236 Tetrapisispora ...
XP_002555426 133 -qarAHLLLKDIMLRVRMMANtd-----plLLKAVLLFEVqqkprginlpgsndssqnapppskrprsdyrsgapnnLNS 206 Lachancea therm...
XP_003675112 153 dsetTHSILRDILLRLRVIANese----gtQMQTLLLFPKdefkisvpvgdt--------------grykrmrsnhnGNS 214 Naumovozyma cas...
CCF60237     111 -ssqAHELLKMVFLRVRGSYSg-------gKLKTLVLNRTgsvpvpkr----------------------kklktesSNG 160 Kazachstania af...
XP_003684892 147 snekSHYLLREAMLKLRVMANqytpseeetSLKTVLQFPVtevfastskdlsqn---------kkngkrmknkqhikGNT 217 Tetrapisispora ...
4EQ6_A       132 spqrSHELLRDTLLKLRVMGNden---enaSIRTLLEFPKeqlldyylkknnnt---------rtssvrskrrriknGDS 199 Saccharomyces c...
Feature 1        #  #  #####   
4DT1_A       199 LAEYIWKYYADSLF 212 Saccharomyces cerevisiae S288c
XP_002494427 218 VGDYIVKFYADTLI 231 Zygosaccharomyces rouxii
XP_001644558 208 IAEYVTKFYSDRLV 221 Vanderwaltozyma polyspora DSM 70294
XP_446749    200 VGEFVGKYYCDEVA 213 [Candida] glabrata
XP_003680546 198 LAEYVAKFYADEIK 211 Torulaspora delbrueckii
CCH61426     237 LGEYVSKYFSDKTL 250 Tetrapisispora blattae CBS 6284
XP_002555426 207 IAVYLMKFYADRVI 220 Lachancea thermotolerans CBS 6340
XP_003675112 215 LGEYVCKFYADRVM 228 Naumovozyma castellii CBS 4309
CCF60237     161 IYEFTSKYYADIEL 174 Kazachstania africana CBS 2517
XP_003684892 218 VGEYICKFYVDQIV 231 Tetrapisispora phaffii CBS 4417
4EQ6_A       200 LAEYIWKYYADSLF 213 Saccharomyces cerevisiae S288c

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