Conserved Protein Domain Family
BTB2_POZ_ABTB1_BPOZ1

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cd18296: BTB2_POZ_ABTB1_BPOZ1 
second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Ankyrin repeat and BTB/POZ domain-containing protein 1 (ABTB1)
ABTB1, also called elongation factor 1A-binding protein or bood POZ containing gene type 1 (BPOZ-1), is an anti-proliferative factor that may act as a mediator of the phosphatase and tensin homolog (PTEN) growth-suppressive signaling pathway. It may play a role in developmental processes. ABTB1 contains an ankyrin repeat and two BTB domains. This model corresponds to the second BTB domain. The BTB/POZ domain is a common protein-protein interaction motif of about 100 amino acids.
Statistics
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PSSM-Id: 349605
Aligned: 16 rows
Threshold Bit Score: 136.271
Created: 18-Sep-2017
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q969K4       254 RGDLWELPFPCpdg--fnsCPDICFRVA-GCSFLCHKAFFCGrSDYFRALLDDHFreseep-------------atsggP 317 human
XP_013074157 216 SWIVGELPFEPetm--pltYPDVCFIVD-DHRFMCHKAFFCGrSDYFKALLENHFgene----------------nsgnI 276 Biomphalaria gl...
XP_002109220 245 RSDLDELFDNFepln-silRPDLIFCVG-GYKFYGHKVFFCErSDYFKALLLGNFaesivs-------------ncseeI 309 Trichoplax adha...
EDO45347     260 FPFSLSLPNDDripgdlpsYTDICINVQ-GNKFFCHKMFLCGrSDYFRALLIDHFaevst---------------epnsI 323 starlet sea ane...
KDR13014     261 WVTGVDLPLMPivp---lfLVDICFCVC-GCKFYCHKAFFCGrSEYFNALLRDHFsett----------------addgN 320 Zootermopsis ne...
ELT89442     255 CQDAAELPFLPert---enFADIIFQVE-NHKFECHKSFFLLrSDYFKALVNDHFgecme--------------dettsL 316 Capitella teleta
EFX90420     256 KHSFTEIPSPLl------nLVDVCFVVD-DHQFLCHKAAFVGrSEYFRALFRDHFretsrtdvcdkaikqtegmegrseI 328 common water flea
OTF78923     201 FVDQDENYDFTaies-kqmTGDVVFQVE-NHLFRCHKLFFAGrSDYFAALLRDHFlesd----------------nrraV 262 Euroglyphus maynei
CDW54377     699 TKENDEAVELTs-------FYDVIFELD-SSRFRCHQAFFCLkSEYFRTLLHSPLvrres---------------nigaC 755 human whipworm
ESA02172     258 TNFLKNVLLGGkq-----yFYDYSDKKVeDEILPCHKAVFTGrSEYFNAMFNGPFaks------------------imkQ 314 Rhizophagus irr...
Q969K4       318 PAVTLHGiSPDVFTHVLYYMYSDHTELspeAAYDVLSVADMYLLPGLKRLCGRSLAQMLD 377 human
XP_013074157 277 PVVYLHEvSIDVFLRILTYIYSDSADLnpeIVSDVLVAADMYLLSGLKRLCGTSLMEYVD 336 Biomphalaria glabrata
XP_002109220 310 PVINLNDcTPDIFSIVMVFIYAGDVKIpcdLTQEILYAADKYLIPGLKRHCCKVIIQNLQ 369 Trichoplax adhaerens
EDO45347     324 PELALHDvTPEVFAAVVSFVYRDNAELtdeILYNVLCAADIYLLHGLKRLCEHKISGLLD 383 starlet sea anemone
KDR13014     321 PMVTIRNvPVEAFASVVYYIYTNAVQAreeYILDVLCAADMYLLPGLKRGCGVVLGSCLS 380 Zootermopsis nevadensis
ELT89442     317 PIIKIQDfSPSTFVQIISYVYQDSCELtekNIFDILYASDLYLLPGLKKQCSNLLAQYID 376 Capitella teleta
EFX90420     329 DLMTLRDvTPEVFAQVVSYVYSNCVQLsaeNVYELLNIGELYLMPGLKKLCANFLISVID 388 common water flea
OTF78923     263 SKFVISD-HADLFRLLICFLYTNDVDItldQACYLLYVSDHYLIESLKRHCATVIGNNID 321 Euroglyphus maynei
CDW54377     756 DSIKLGQfSDSVFKYVITHVYCEDVKLdveTVDDVLMVANFCLLPGLKRQCGLLMAQHLD 815 human whipworm
ESA02172     315 PIVTVSDlSPGIFALILEFIYTDKCDIpdsAAYEVLIKADMFLLDKLKSLASIVLTSSSE 374 Rhizophagus irregularis DAOM 181602
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