Conserved Protein Domain Family
BTB2_POZ_BTBD8
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cd18286: BTB2_POZ_BTBD8 
second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 8 (BTBD8)
BTBD8 is a BTB-domain-containing Kelch-like protein that may play a role in developmental processes. It may also act as a protein-protein adaptor in a transcription complex and thus be involved in brain development. BTBD8 contains two BTB domains. This model corresponds to the second domain. The BTB/POZ domain is a common protein-protein interaction motif of about 100 amino acids.
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Statistics
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PSSM-Id: 349595
Aligned: 18 rows
Threshold Bit Score: 133.153
Created: 18-Sep-2017
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q5XKL5        189 ASELGEDLLKLYVKPcCPDIDIFVDGKRFKAHRAILSArSSYFAAMLSGcwae---ssqEYVTLQGi---sHVELNVMMH 262  human
ELU05169       22 CCPLGKDILHMYLQGdDHDVSLKIDSTSFRAHKCILCArSGYFAAMLSGpwse---snsDEIELIGv---aPEAMEIILL 95   Capitella teleta
EKC19304     1070 CSVLGEDLLRGFLQDlDYDCIITVSDVHFKAHRSLLTArSAYFEAMLSGswve---sdsHEIKLEGv---tPGVMEQTLL 1143 Pacific oyster
XP_002739164  243 TCDLARDLLRMFVKQkATDIGLRVQGRLIKAHRFVLCCrSVYFTAMLCGgwae---staEEIYLHDv---sCSTALAALY 316  Saccoglossus ...
XP_022099107  307 SCRLGRDLLGIFTDDsAPDVIIKVDGKEIPAHRFMLCArSQYFAAMLLGswre---sssCEIELTSf---tYAAVILALR 380  crown-of-thor...
XP_013414220  261 CDDIAKDLIELYLSGeNGDVILKVGEVTFKCHRCILALrCSYFEAMLGGgwae---sqaGEIKLERl---nPAALHQLLL 334  Lingula anatina
XP_002126232  146 RSILADCLIQLLLNGfHYDLKIRVKSETFLAHKSVLYCrSSYFQAMLRNdhggwvetesKVISLEGv---sVENFAILLL 222  vase tunicate
NP_647628    1110 PRRLGEDLLKMFLQEiATDMLVEVHGRRIRAHKCILRSrCQYFAAMLAGhg------sqSVVSLQGy---sYAAVHFALC 1180 fruit fly
EEC03254      735 CSKLGDDLLRMFVGQvETDIFVRVEGKDIGAHRFILASrSEYFSSLLKDqd------aeSVIFMDGf---tHAAVLFSLH 805  black-legged ...
KRY83110      227 CSALGTDLLCMFLTGqGVDCTIRSRSAQFNVHKCILSAvSSYFATLFSDqwq-----nsSECKLPEissfsNEAVSFMLM 301  Trichinella p...

Q5XKL5        263 FIYGGTLDIpdk--tnVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQ 309  human
ELU05169       96 YMYGAVPNLdps-qcnITHVLAAADMYGLCGLMESVAYALRRYYCHFFH 143  Capitella teleta
EKC19304     1144 YLYGGVTDLids--ctLSELIMVADMYGLDGLRDVVLYNLRRDYCHFFH 1190 Pacific oyster
XP_002739164  317 YVYGGVMEHpnd--anIGELVQMSDMYGLDGLKDNAAFILRRDKCHFFH 363  Saccoglossus kowalevskii
XP_022099107  381 FIYGGAYELpdg--viLRDVLYMADMYALDMLKDVVVFKLRKDYCHFFH 427  crown-of-thorns starfish
XP_013414220  335 YIYGGCVNLdgt-dcsILDMVMAGDMYDVPGFKDAVEFLIRRDYCHHFH 382  Lingula anatina
XP_002126232  223 FIYGALVDLseftfdeLISLASDADMYATMFVMNAVEFYVKKEKCHFFH 271  vase tunicate
NP_647628    1181 HIYSGASHPpdg--isLMELAALADLLGLEGLKEVTAHALKTNYCHNFH 1227 fruit fly
EEC03254      806 HLYGGAALPpke--vhVSELALLAEMLGLDGLRRVVLSHIRTYYCHFFH 852  black-legged tick
KRY83110      302 FIYGGVLEIpdn--vdLIELYRLADITRLDALKTLAVLELRAKRCHYFH 348  Trichinella pseudospiralis
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