Conserved Protein Domain Family
BTB_POZ_ZBTB34
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cd18220: BTB_POZ_ZBTB34 
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 34 (ZBTB34)
ZBTB34 acts as a transcriptional regulator. It downregulates specificity protein (Sp) transcription factors Sp1, Sp3, and Sp4 in pancreatic cancer cells. It contains a BTB/POZ domain, a common protein-protein interaction motif of about 100 amino acids.
Links
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Statistics
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PSSM-Id: 349529
Aligned: 7 rows
Threshold Bit Score: 230.682
Created: 13-Sep-2017
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q8NCN2         7 IQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALsTMSGLSISVIKNPNVFEQLLSF 86  human
XP_018423171  53 IQFEVPEYSSTVLSQLNELRMQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALsTMSGLSISVIKNPNVFEQLLSF 132 Nanorana parkeri
XP_005987367  29 IQFDVPEYSNTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALsTMSGLSISVIKNPDVFEQLLSF 108 coelacanth
XP_007909612   7 IQFEVAEYSNCVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALsTMSGLSISVIKNPDVFEQLLAF 86  elephant shark
NP_001012813   7 IQFDVPEYSNTVLSQLNELRLQGKLCGIIVHIQGQPFRAHKAVLAASSPYFRDHSALsTMSGLSISVIKNPNVFEQLLSF 86  chicken
NP_001116183   8 IEFDVPEFSNTVLNQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSSLgTMSGLSISVIKSPEVFEQLLAF 87  zebrafish
OCT65257       7 IQFDVPEYSNTVLSQLNELRMQGKLCDIVVHIQGQPFRAHKAVLAASSPYFRDHSALsNMSGLSISVIKNPNVFEQLLSF 86  African clawed ...

Q8NCN2        87 CYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIH 126 human
XP_018423171 133 CYTGRMSVQLKDVVSYLTAASFLQMQCVIDKCTQILENIH 172 Nanorana parkeri
XP_005987367 109 CYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIH 148 coelacanth
XP_007909612  87 CYTGRLSLHLKDVVSFLTAASFLQMQCIIDKCTQILESIH 126 elephant shark
NP_001012813  87 CYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIH 126 chicken
NP_001116183  88 CYTGRMALRLRDVISFLTAASFLQMQAVIDKCTQILEGIH 127 zebrafish
OCT65257      87 CYTGRMSVQLKDVVSFLTAASFLQMQCVIDKCTHILETIH 126 African clawed frog
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