Conserved Protein Domain Family
BTB_POZ_ZBTB23_GZF1
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cd18211: BTB_POZ_ZBTB23_GZF1 
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 (GZF1)
GZF1 is also called GDNF-inducible zinc finger protein 1, zinc finger and BTB domain-containing protein 23 (ZBTB23), or zinc finger protein 336 (ZNF336). It is a sequence-specific transcriptional repressor that binds the GZF1 responsive element (GRE), with the consensus sequence of 5'-TGCGCN[TG][CA]TATA-3'. It may play a role in renal branching morphogenesis. It contains a BTB/POZ domain, a common protein-protein interaction motif of about 100 amino acids.
Links
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Statistics
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PSSM-Id: 349520
Aligned: 5 rows
Threshold Bit Score: 228.97
Created: 14-Sep-2017
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9H116         6 VLLESKSSPFNLLHEMHELRlLGHLCDVTVSVEyqGVRKDFMAHKAVLAATSKFFKEVFLneksvdgtrTNVYLNEVQVA 85   human
NP_001039101   6 VLLESKSLPMNLLNEMYQLRlLGHLCDVTVRVEhhGSKMEFSAHKSVLAASSKYFKEVFInsnildcpnAYIHLNEIPSV 85   tropical clawe...
NP_001336668   6 VLLESKSSPINLLNEMHQLRlLGHLCDVTVSVEyqGVRAEFVAHKAVLAATSKFFKEVFLneksmdgprTNVFLNEVQVA 85   chicken
XP_014341125  14 VTMESKAAASNLLNALHKLYqFGHLCDATVQTEhhGIQEEFSVHKAVLAASSNYFKELFLsdeisnaknTTVMLQDIYTE 93   coelacanth
XP_007892695   6 VVLESKAAPKTLLDEMHKLRiLCYFCDVTVQIEhqGSKEEFVAHKAVLAAASSYFKELFLnemv-ntkiTIVTLRDIYTA 84   elephant shark

Q9H116        86 DFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLDLSETCFQLKKQML 133  human
NP_001039101  86 DFASFLDFVYTARVEVEEDRVQRMIDVAEKLRCPELAETCFQLKKQML 133  tropical clawed frog
NP_001336668  86 DFASFLEFVYTAKVEVEEDRVQRMLEIAEKLKCLDLSETCFQLKKQML 133  chicken
XP_014341125  94 EFTSFLEFVYTAKIEIESDRLYRMKEIAERLECKDLLEVCEDIKAKTV 141  coelacanth
XP_007892695  85 DFASFLDFVYTAKVEVEAERVQRLQEIAEKLKCRELVEVCSQVKSQIL 132  elephant shark
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