Conserved Protein Domain Family
DEXHc_CHD6_7_8_9
?
cd17995: DEXHc_CHD6_7_8_9 
DEXH-box helicase domain of the chromodomain helicase DNA binding protein 6, 7, 8 and 9
Chromodomain-helicase-DNA-binding protein 6-9 (CHD6, CHD7, CHD8, and CHD9) are members of the DEAD-like helicases superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Links
?
Statistics
?
PSSM-Id: 350753
Aligned: 20 rows
Threshold Bit Score: 356.558
Created: 3-Feb-2014
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Download Cn3D
 
ATP bindingDEAD box
Feature 1:ATP binding site [chemical binding site]
Evidence:
  • Comment:based on the structure of Saccharomyces cerevisiae Chd1 with bound gamma-thio-ATP
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                                  #######                                   #         
Q06A37     969 LREYQLEGVNWLLFNWy-nTRNCILADEMGLGKTIQSITFLYEIYlkg---ihGPFLVIAPLSTIPNWEREFRTWTelNV 1044 chicken
CBK22066   166 LRPYQVEGVNWMLWNWf-nNRNSILADEMGLGKTVQSTLFIQQILhry--ktkPPFLIVAPLSTLPHWEAEIARWTdlHV 242  Blastocystis hom...
CCA15572   400 LRDYQLTGVNWMLFNWy-hSRNSMLADEMGLGKTVQTVTFINHLAtte--glpGPYLIIAPLSTLAHWQREFSNWCclNA 476  Albugo laibachii...
CBN74034   410 LRDYQREGVRWIIYNWl-qGRGSILADEMGLGKTLQTVAFLSILHnvy--gkrGPFLVIAPLSTVPHWLREFQTWSdmNA 486  Ectocarpus silic...
CCA16095   441 LRIYQLEGLNWLLWNWy-nERPSILADEMGLGKTIQTLAFLDRLRvdpkiqcrGPFLIVAPLSLIVQWQNECETWTcmNC 519  Albugo laibachii...
EGG16642   589 LKEFQVEGFLWLSYNWy-hERSSLLADEMGLGKTIQSIAFLTYLSqsv--gikGPFMVVAPLSTLGNWQKEILKWTdmRV 665  Dictyostelium fa...
CCA22651   885 LRSYQVEGLNWIISCWk-aQRSCILADEMGLGKTIQVAAVLEHFVtee--sirGPFLIVVPLSTIQHWRRELQGWTdlNV 961  Albugo laibachii...
CBK23191   712 LRDYQVVSLNWMVEKWr-aHEGMILGDEMGLGKTIQVIALLHHFItve--nqeGPYLVISPLSTLKNWLREFATWTsiRV 788  Blastocystis hom...
CBJ27936  1974 LRDYQRRGVNWMLSCWkkkKRGCILADEMGLGKTVQVVAMLNYVFsnse-rerGPFLVVVPLTTIEHWRREVEAWTdmNL 2052 Ectocarpus silic...
CBK21472   145 LRPYQWEGFRWLKDNYn-qGKNSILADEMGLGKTIQVISLMEHIIhnm--etqQPILVIAPLSTLGFWRREIESWTtlNV 221  Blastocystis hom...

Feature 1                                                                                      
Q06A37    1045 VVYHGSqasrrtiqlyemyf------------------------------------------kdpqgrvikgsykfHAII 1082 chicken
CBK22066   243 VVFHGRvesrriikqy---------------------------------------------------ewksqegefDILL 271  Blastocystis hom...
CCA15572   477 VVYHGTyearkliekhefyltakefgdamlsmgkfwgdskktrkrrrtlekslvrekadrisvpagartprqfirfDVLI 556  Albugo laibachii...
CBN74034   487 VVFHGDpedreilegyemefagdk----------------------------------graekdktrikgkrvwksTVVI 532  Ectocarpus silic...
CCA16095   520 IVYHGNtearevireyefyfm-----------------------------------------nengkpdkkkpfrfHIIV 558  Albugo laibachii...
EGG16642   666 LVFYGTqetrafqkkye------------------------------------------------wkrkdkgvyqfEILL 697  Dictyostelium fa...
CCA22651   962 CVYHDIgdrqnrgfnskdmramir-----------------------------------mhewyypdrgnssifrfHALL 1006 Albugo laibachii...
CBK23191   789 CCYHSEgkgkderqliqayn------------------------------------------wffkglparglykfNVLL 826  Blastocystis hom...
CBJ27936  2053 CMYHDNggrdmrdlireye--------------------------------------------wyysgrskrvlkfHVLV 2088 Ectocarpus silic...
CBK21472   222 VMYHDNeggkdirhlieryefyy-------------------------------------trkqlpvpppfpvykfDILL 264  Blastocystis hom...

Feature 1                                ##                                                    
Q06A37    1083 TTFEMILTdcpel---rnipWRCVVIDEAHRLKnrnCKLLEGLKMMDl--------EHKVLLTGTPLQNtveELFSLLHF 1151 chicken
CBK22066   272 TTFQICIAeaaal---ssisWAGLVVDEAHRLKgknNKLGDVLKKIDf--------GCKLLLTGTPLQNnteELWILLNF 340  Blastocystis hom...
CCA15572   557 TTFEMLGAsdshr--lsridWQVVVVDEAHRLKnfnSKSANIMRKSIk-------yQNILLLTGTPLQNnveELWTLLHL 627  Albugo laibachii...
CBN74034   533 TTPELCIRkdvktllqrriaWDVLVVDEAHRLKnsaSRLNVVLKDYTf--------ESSLLLTGTPLQNnteELWTLLNL 604  Ectocarpus silic...
CCA16095   559 TTYEVAIKdiafl---skirWRCLIVDEAHRLKnqsSRLVEQLRSLRr--------DHCVLLTGTPLQNkteELWALLNF 627  Albugo laibachii...
EGG16642   698 TTYETVMAehqdl---vkinWRALVLDEGHRIKntqSKVLSKLKSIKt--------EHSVILTGTPLQNdmkELWTMLNF 766  Dictyostelium fa...
CCA22651  1007 TTFETILAdfeef---esihWRLLIVDEAHRLKsagSRVLKQMRVLHc--------DRKLLLTGTPLQNnmqELWVLINF 1075 Albugo laibachii...
CBK23191   827 TTYEVVMKdwgvl---gdiaWEGVVMDEAHRMRnnnCKFMQFISKVKt--------EHKLLLTGTPLQNntgELWPLLNF 895  Blastocystis hom...
CBJ27936  2089 TTYDDVISdaeml---aqvpWRAVVVDEAHRMRnknSALLGCLQQVVhngmavnayQHRVLMTGTPMQNikeELWPLMNF 2165 Ectocarpus silic...
CBK21472   265 TTYEIANTdvdel---rnirWSLVVVDEAQRMKnksGKLQQTLHQIHw--------QQCVLLTGTPLQNnmlELWTLLNF 333  Blastocystis hom...

Feature 1                                                
Q06A37    1152 LEPgrfpsettFMQEFGDLKTeeq---vqkLQAILKPMMLRR 1190 chicken
CBK22066   341 LQPerfhdaeqFQADFGDMKVaaq---lekLHTLLKPLMLRR 379  Blastocystis hominis
CCA15572   628 LDRgrfrskeaFLEEYGDLKEhsq---vekLHADLKPYLLRR 666  Albugo laibachii Nc14
CBN74034   605 VDEpkfrdqqgFVEKYGDLQEaed---vseLQEAIKPYLLRR 643  Ectocarpus siliculosus
CCA16095   628 LDTrsfpsveeFLDKFGDLHQarq---vadLHKMLKPYLLRR 666  Albugo laibachii Nc14
EGG16642   767 LDPdkfasstqFLDEFSDLKEesq---vqrLHQILAPYLLRR 805  Dictyostelium fasciculatum
CCA22651  1076 LEPvkfaswedFEAKFGRLQSheq---vvtLQKLLAPYVLRR 1114 Albugo laibachii Nc14
CBK23191   896 IEVkeagtmarFKEAFGDLRSneq---vekLRALLASCMLRR 934  Blastocystis hominis
CBJ27936  2166 IDQsnfpdlqrFQEKYCKGEPghevdearaLRRRLKPYMLRR 2207 Ectocarpus siliculosus
CBK21472   334 VAPqtfpssteFLQQYGDLHNqsq---vasLQRLLVTYVLRR 372  Blastocystis hominis

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap