1N0E,1N0E,1N0E,1N0E,1N0E,1N0E,1N0E,1N0E


Conserved Protein Domain Family
MraZ
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cd16319: MraZ 
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protein domain of unknown function (UPF0040) includes MraZ
This family contains proteins of unknown function (UPF0040), implicated in a cellular function of bacterial cell division. It includes protein MraZ which is present in almost all bacteria and appears to be essential for survival. It is found in gene clusters associated with the cellular function of cell division and cell wall biosynthesis. Members of this family contain two tandem copies of the domain; the crystal structure of a member of this family (MPN314) reveals that the two subdomains are related by a pseudo two-fold axis, with each subdomain containing a highly conserved DXXXR sequence motif in close proximity to each other, suggested to form the functional site.
Links
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Statistics
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PSSM-Id: 293782
Aligned: 8 rows
Threshold Bit Score: 80.0284
Created: 28-Mar-2013
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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oligomerDXXXR
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:oligomer interface [polypeptide binding site]
Evidence:
  • Comment:MPN314 is an octameric ring-shaped structure. Eight monomers are arranged to form a pseudo 8-fold symmetry; this octameric form is suggested to be the biological aggregation state
  • Structure:1N0E: Mycoplasma pneumoniae MPN314 (protein MraZ)
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1     #                           #       #        ##  #   
1N0E_A     30 TFNITLDaKNRISLPAKLRAFFe--GSIVINRGfenCLEVRKpQDFQKYFEQF 80  Mycoplasma pneumoniae
1N0E_A    101 ANFVDVDtAGRVLIPNNLINDAkldKEIVLIGQf-dHLEIWDkKLYEDYLANS 152 Mycoplasma pneumoniae
1N0E_C     30 TFNITLDaKNRISLPAKLRAFFe--GSIVINRGfenCLEVRKpQDFQKYFEQF 80  Mycoplasma pneumoniae
1N0E_C    101 ANFVDVDtAGRVLIPNNLINDAkldKEIVLIGQf-dHLEIWDkKLYEDYLANS 152 Mycoplasma pneumoniae
1N0E_E     30 TFNITLDaKNRISLPAKLRAFFe--GSIVINRGfenCLEVRKpQDFQKYFEQF 80  Mycoplasma pneumoniae
1N0E_E    101 ANFVDVDtAGRVLIPNNLINDAkldKEIVLIGQf-dHLEIWDkKLYEDYLANS 152 Mycoplasma pneumoniae
1N0E_G     30 TFNITLDaKNRISLPAKLRAFFe--GSIVINRGfenCLEVRKpQDFQKYFEQF 80  Mycoplasma pneumoniae
1N0E_G    101 ANFVDVDtAGRVLIPNNLINDAkldKEIVLIGQf-dHLEIWDkKLYEDYLANS 152 Mycoplasma pneumoniae

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