2WYM,3BV6


Conserved Protein Domain Family
UlaG-like_MBL-fold
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cd16284: UlaG-like_MBL-fold 
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UlaG a putative l-ascorbate-6-P lactonase and related proteins; MBL-fold metallo hydrolase domain
UlaG is essential for L-ascorbate utilization under anaerobic conditions; it is a putative l-ascorbate-6-P lactonase thought to catalyze the hydrolysis of L-ascorbate-6-phosphate to 3-keto-L-gulonate-6-phosphate. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.
Links
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Statistics
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PSSM-Id: 293842
Aligned: 14 rows
Threshold Bit Score: 329.812
Created: 8-Sep-2015
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1:putative active site [active site]
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                     
2WYM_F     37 TFAMWWLGCTGIWLKSEGGTNVCVDFWCgtgkqshgnplmkqghqmqrmagvkklqpnlrttpFVLDPFAIRQIDAVLAT 116 
3BV6_A     61 TFSMWWLGCTGIWLKSAGNTNLSIDFWCgtgkktqknrlmntqhqmmrmggvealqpnlrtsiFPLDPFAIKEIDAVLAS 140  Vibrio cholerae O...
ACZ07026   37 TFAMWWLGCTGIWVKSEGNTNIVIDFWCgtgkrtkknklmkkqhqmqrmvgglklqpnlrtsvFVLDPFAIKELDAVLAT 116  Sebaldella termit...
EDT16471   37 TFSMWWLGCTGIWLKTQGNTNICIDFWCgsgkrtkknpyinpehqmarmcggkklqtnlrvapFVLDPFAIKNVDAIIST 116  Clostridium perfr...
ADK79462   37 TFAMWWLGCTGIWVKSEGNTNICIDLWTksgkrtkqnplmkeqhqhqrmigcrklqpnlrnvpCVIDPFAIRKVEAILAT 116  Spirochaeta smara...
AIF50325   37 TFAMWWLGCTGIWIKSEGSANICIDFWCgsgkrtkskplmdshhqmarmtggkklqpnlrvapFVLDPFAINKIDAVVST 116  Pelosinus sp. UFO1
CSV60986   37 TFAMWWLGCTGIWLKSEGGTNVCVDFWCgtgkqshgnplmkqghqmqrmagvkklqpnlrttpFVLDPFAIRQIDAVLAT 116  Shigella sonnei
EHX41529   37 TFAMWWLGCTGIWLKSEGGTNVCVDFWCgtgkqshgnplmkqghqmqrmagvkklqpnlrttpFVLDPFAIRQIDAVLAT 116  Escherichia coli ...
EUJ45947   37 TFSMWWLGCTGIWLKTHENTNLLVDLWCgtgkqtrknqwmkdghqmqrmsgckklqpnlrtmpFVIDPFAIKDLDALVVT 116  Listeria riparia ...
KGQ13367  681 SVAMWWLGCVGLWVKTPGNANVSIDFWCgtgkrkknlpdmkpshqmarmsgariaqpnlrstpFVLDPFSIKEIDAVLAT 760  Beauveria bassian...

Feature 1     # # ##                                                                          
2WYM_F    117 HDHNDHIDVNVAAAVMQNcADDVPFIGPkTCVDLWIGWGvpkERCIVVKPGDVVKVKDIEIHALDAFdrtalitlpa-dq 195 
3BV6_A    141 HDHADHIDVNVAAAVLQNcGEHVKFIGPqACVDLWLGWGvpqERCIVAKVGDVLEIGDVKIRVLDSFdrtalvtlpkgvs 220  Vibrio cholerae O...
ACZ07026  117 HDHADHIDPNVAAAVLKNcDPSVPFIGPqACVDLWISWGvpaERCKAVKPGDTVKIKDIELVVLESFdrtelvtape-gv 195  Sebaldella termit...
EDT16471  117 HDHNDHIDINVAAAVLKNcSEDVPFIGPqACVDKWIGWGvpkERCIVVKPGDVIKIKDIQLHALESFdrtalitapp-eg 195  Clostridium perfr...
ADK79462  117 HDHGDHIDENVAAAVLQNiSAEVPFVGPqACVDLWTSWGvpkERCRVVRPGDSLQIGDVQIIVLDSFdrtelvtapk-gv 195  Spirochaeta smara...
AIF50325  117 HDHNDHIDVNVAAAVMKNcDSSVPFIGPkTCVDLWIGWGvpaERCIVVKPGDVVKIKDTELVVLESFdrtalitvpk-ge 195  Pelosinus sp. UFO1
CSV60986  117 HDHNDHIDVNVAAAVMQNcADDVPFIGPkTCVDLWIGWGvpkERCIVVKPGDVVKVKDIEIHALDAFdrtalitlpa-dq 195  Shigella sonnei
EHX41529  117 HDHNDHIDVNVAAAVMQNcADDVPFIGPkTCVDLWIGWGvpkERCIVVKPGDVVKVKDIEIHALDAFdrtalitlpa-dq 195  Escherichia coli ...
EUJ45947  117 HFHSDHIDINTAAAVMQNcAEDVPFIGPqACVDIWTGWGvpkERCIVVHPGDVVKVKDVEIVVLEAFdrtalvtvpe-dv 195  Listeria riparia ...
KGQ13367  761 HYHADHIDINVAAAVLKNcSPEVPFIGPqACVDLWMQWGvpaERCRVVKPGDVIKIKDMEIAVLESSdrtiliteppkpl 840  Beauveria bassian...

Feature 1             ##                    #                      #
2WYM_F    196 kaagvlpdGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSY 249 
3BV6_A    221 sydkaildGMDERAVNYLIETSGGSVYHSGDSHYSNYYAKHGNDYQIDVALLSY 274  Vibrio cholerae O1 biovar El Tor str. N16961
ACZ07026  196 ilkdkmpqDMDRLAVNYLVKTPGGNLYHSGDSHYSNYYAKHGNEHKVDVALGSY 249  Sebaldella termitidis ATCC 33386
EDT16471  196 dlrgkmpvDMDYKAVNYLIETPGGNLYHSGDSHYSNYYAKHGNDYKIDVALGSY 249  Clostridium perfringens E str. JGS1987
ADK79462  196 vlkgkmpqDMDRLAVNYLIKTPGGTIYHSGDSHYSNYYAKHGNDHEIDVALGSY 249  Spirochaeta smaragdinae DSM 11293
AIF50325  196 tltgkmpgNMDERAVNYLVKTTGGSLYHSGDSHYSNYYAKHGNDHKVDVALGSF 249  Pelosinus sp. UFO1
CSV60986  196 kaagvlpdGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSY 249  Shigella sonnei
EHX41529  196 kaagvlpdGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSY 249  Escherichia coli DEC12E
EUJ45947  196 tlagkmpmDMDEVAVNYLFNTSGGSLYHAGDSHYSNQFAKHGNDHKIDVALGAY 249  Listeria riparia FSL S10-1204
KGQ13367  841 addgaaipDMDLRSVNYLLKTPGGNIYHSGDSHYSNMYAQHGKQHNIDVALGSF 894  Beauveria bassiana D1-5

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