2FGT


Conserved Protein Domain Family
YycH_N

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cd15787: YycH_N 
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N-terminal domain of YycH and similar proteins
This protein appears to be a member of a somewhat larger structural family conserved in Firmicutes. YycH plays a role in signal transduction and is found immediately downstream of the essential histidine kinase YycG. YycG forms a two-component system together with its cognate response regulator YycF. YycH functions as a modulator of YycG activity, possibly by interacting with YchI. All three molecules (YchG, YchH, and YchI) have been characterized as membrane proteins, and they may be able to form homodimers. This model describes the N-terminal domain of YycH.
Statistics
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PSSM-Id: 276948
Aligned: 201 rows
Threshold Bit Score: 46.5514
Created: 26-Sep-2014
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2FGT_A        13 KTTQKLSETVRPRDMFIHDDGAHYKVDd---nALYEEIWSDLPHwdVKGIKDISDQyd---kaGFKSWFYgiggSEAKLD 86  Bacillus subtilis
WP_026702049  46 GEELQLEEVVEPDQLILHDGDSHASLN-----ATDALFSRFYEDllDSRFENITLNqe----vNEDDIYE----GQRSAE 112 Bacillus aiding...
WP_026675542  47 SEERSLTDIIAPQQVILHNNEDVASLD-----LNDVLFEELYEQlvATNVEDLTVV-------SWDLASPl---KSQSIE 111 Bacillus bogori...
YP_004097262  46 GEERSLEELIQPKQVITHEEDNSFWIQ-----PTNNHYLLLMEElkQVNIQEIRRGs-----nSFARTIN----DVQGIE 111 Bacillus cellul...
YP_003701347  48 GESRSLFELIFPREILAHQEDDVDLLL-----AGNGLYEGILEEimDTEFHYVTERa-----gNLAPHPDh---RFTGLE 114 Bacillus seleni...
WP_022792972  47 AETREAGEVVRPNQGVVRANGRSVLMTedqasADLDKVFRQLEEasITETTATDLEh-----dELYQNAAs---AAYSME 118 Marinococcus ha...
WP_023510252  46 AQTRKLTDVIRPNLMLELNSNGEFGQNs---yGRIQKVYSLLQQsvFNKLTTYNNKvsrgdnpSYKLIFPap-lTRDALT 121 Sporolactobacil...
WP_028978113  46 AESRKFPQVIRPNLMLERNQNGRFGQNs---nTDIQKVYSLLRQsvFSEITGSASSl------EDADTPHy--tLVFPAP 114 Sporolactobacil...
WP_026691766  47 GVEKSHVDLLIPESITIHENEERYWLE-----PEEERFTSQMEAllDVEFERVVDYp-----rSGVPVLNq---PARAID 113 Bacillus aurant...
WP_026697149  50 GESKSLTELLYPSQVISYEDEERFWIH-----PAGDNYEELLTA--LEEVELEAMTp-----vSTDVLAEpg-eSLQGVE 116 Bacillus chagan...
2FGT_A        87 LQFsd----tiPIDIFQTLFkw----------sNQSFEYSSf-----DHILIPFNEt--KANKKIYLVSYs--------- 136 Bacillus subtilis
WP_026702049 113 IIYpt----pvPDEIMEQMLr-----------fEEDSPNLSmd--siDRIVLQDQGg-dTDTLIVKFISHe--------- 165 Bacillus aiding...
WP_026675542 112 FVYpt----siPAEVILNMFpni--------geDTILPTESv-----DRLILYHVTt--KDKIHLRMVSYeeqvsfdfat 172 Bacillus bogori...
YP_004097262 112 LLFshei-kgeWIHRFFEMDq------------EEPFPMEGl-----DRIIIFINEqssETEVSVRFMSTs--------- 164 Bacillus cellul...
YP_003701347 115 VVFqe----plPADIVYDVLdf----------eDDSLPFSGl-----DRMRIVENPsriGSDVVAQFVDMn--------- 166 Bacillus seleni...
WP_022792972 119 LVFps----svSWSMINELFsf----------eDESDEAASildgsvDRIILTASPg--SEELNAAFVSYd--------- 173 Marinococcus ha...
WP_023510252 122 KVFqfdekssiPNEALIDRIelfsssngqritaIFSSPDEK------DKLYATVDHm-nMNNLKALFTGTklypyd---- 190 Sporolactobacil...
WP_028978113 115 LTFd-------ALGRVFQFDs------------SKSVSANHip---vDRIDIFGSTd--KQNVIAVFSSPd--------- 161 Sporolactobacil...
WP_026691766 114 YKFhs----piPGSTINELFdf----------gEETIAITSv-----DRIYITRSTtsaNGEVIARFISTe--------- 165 Bacillus aurant...
WP_026697149 117 VFFde----alEDNWLPFLF-------------DIEEEDILve--nvDRMMILETEgedTADVVVRFVDEe--------- 168 Bacillus chagan...
2FGT_A       137 ------kQLILEVTVESAn-------------------YRNIMNDLKNRQ 161 Bacillus subtilis
WP_026702049 166 ------eSFVLEGETNFSlsafre---------eyvlqMDDYTSVFPYQL 200 Bacillus aidingensis
WP_026675542 173 sfsigdfQNVYLAKASEFipvfsy--------ekrnddYERFTKHIYLPS 214 Bacillus bogoriensis
YP_004097262 165 ------eDVLYQANTNLS--------------------ATSLISLYEQYE 188 Bacillus cellulosilyticus
YP_003701347 167 ------eETVYETDTDMG--------------------LGLLEELIAEGS 190 Bacillus selenitireducens
WP_022792972 174 ------qGVIVNSNTSLDksdie-----------yeryLSEHENMLTYSA 206 Marinococcus halotolerans
WP_023510252 191 -rqplkgKVVYLPDDKTKmh----------------seVSYYEKLKLEEF 223 Sporolactobacillus laevolacticus
WP_028978113 162 ------eKNKFYTTVDHLn-------------------FETLQGLYAKAE 186 Sporolactobacillus terrae
WP_026691766 166 ------dEEIYQAETNLNndqlvamyegerdhmyeargVSFDEENLYGDY 209 Bacillus aurantiacus
WP_026697149 169 ------eEEVFESDTALSps-----------------eMRSFRQGIVTER 195 Bacillus chagannorensis
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