Conserved Protein Domain Family
PHD_HAC_like
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cd15614: PHD_HAC_like 
PHD finger found in Arabidopsis thaliana histone acetyltransferases (HATs) HAC and similar proteins
This family includes A. thaliana HACs (HAC1/2/4/5/12), which are histone acetyltransferases of the p300/CREB-binding protein (CBP) co-activator family. CBP-type HAT proteins are also found in animals, but absent in fungi. The domain architecture of CBP-type HAT proteins differs between plants and animals. Members in this family contain an N-terminal partially conserved KIX domain, a Zf-TAZ domain, a Cysteine rich CBP-type HAT domain that harbors a plant homeodomain (PHD) finger, a Zf-ZZ domain, and a Zf-TAZ domain. PHD fingers can recognize the unmodified and modified histone H3 tail, and some have been found to interact with non-histone proteins.
Links
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Statistics
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PSSM-Id: 277086
Aligned: 15 rows
Threshold Bit Score: 104.742
Created: 13-Aug-2013
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Zn binding siteputative
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C C H C C CClick to see conserved feature residue pattern help
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1          #  #                                                         #  #    #  #      
Q9LE42        972 VCIPCYNearantvsvdgtpvp---------------------ksrfekkkndeeveESWVQCDKCQAWQHQICALFNgr 1030 thale cress
XP_001692031  421 FCHQCFTdqkgerilvegvsik---------------------ksdlvkrkndeeieEGWVQCDHCEGWVHQICGMFNkg 479  Chlamydomonas...
XP_001775575  919 FCVPCYNevrsenvemegmiyp---------------------ksklekrkndeeteEAWVQCDKCNLWQHQVCALFNgr 977  Physcomitrell...
XP_002964262  627 FCIPCYNaspadtvgldgqlyp---------------------ksklekkkndeeteEAWVQCDKCNVWQHQICALFNgr 685  Selaginella m...
EIE23727      240 WCHSCYSehrgeiiqmegmrvr---------------------knelekrkndeeteEGWVQCDVCDCWVHQICGLFNkg 298  Coccomyxa sp....
CCO17512      556 WCNPCYNtiqghidiegqrfp----------------------knslikkkndddleEPWVQCDFCNNWYHQICVLFNgr 613  Bathycoccus p...
CBK25066      185 YCQKCYAkkivgmdkadrkn-------------------------lfvkkkndevfpESWVQCSRCHEWLHCICGLVHpr 239  Blastocystis ...
EEY69842      269 WCSSCYKqmkdgpidlsllpqlssaatevapppgaipfdgvlkksslvkrknsevaeEPWVECDSCKLWYHQICALFNer 348  Phytophthora ...
EWM29490     1380 WCVPCYQeikgeeihiggtvlk---------------------kselikdkndklreEFWVGCDSCSQWVHQVCALYNgr 1438 Nannochlorops...
EPS69306      103 LCGSCFLkcpgrniligghsfs---------------------klhfqklkhteefeEAWVRCDKCDRRQHQICGLYNsk 161  Genlisea aurea

Feature 1                     #  #
Q9LE42       1031 rn---hgqaEYTCPNC 1043 thale cress
XP_001692031  480 rn---ntdvHYLCPDC 492  Chlamydomonas reinhardtii
XP_001775575  978 rn---egdsEYICPEC 990  Physcomitrella patens subsp. patens
XP_002964262  686 rne--ggdtEFICPYC 699  Selaginella moellendorffii
EIE23727      299 rn---keetPYVCPMC 311  Coccomyxa sp. C-169
CCO17512      614 knt--hgeaHFTCPTC 627  Bathycoccus prasinos
CBK25066      240 q-----vtnNYVCPIC 250  Blastocystis hominis
EEY69842      349 nhaisgeqePFVCPIC 364  Phytophthora infestans T30-4
EWM29490     1439 ndq--geqvKYYCPPC 1452 Nannochloropsis gaditana
EPS69306      162 qnf--eektKYICPFC 175  Genlisea aurea

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