Conserved Protein Domain Family
PHD_OBE1_like

cd15612: PHD_OBE1_like

PHD finger found in Arabidopsis thaliana protein OBERON 1, OBERON 2, and similar proteins mainly found in plants

Included in this family are OBERON 1 (OBE1, or potyvirus VPg-interacting protein 2) and OBERON 2 (OBE2, or potyvirus VPg-interacting protein 1), which have been involved in the maintenance and/or establishment of the meristems in Arabidopsis. They interact with potyvirus VPg-interacting proteins (PVIP1 and 2) and act as central regulators in auxin-mediated control of development. Both OBE1and OBE2 contain a plant homeodomain (PHD) finger. PHD fingers can recognize the unmodified and modified histone H3 tail, and some have been found to interact with non-histone proteins.

Links

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Source:	cd15517
Taxonomy:	Eukaryota
PubMed:	3 links

Protein:	Representatives
	Specific Protein
	Related Protein
	Related Structure
	Architectures
Superfamily:	cl22851

Statistics

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PSSM-Id:	277084
Aligned:	8 rows
Threshold Bit Score:	75.3465
Created:	6-Jan-2014
Updated:	2-Oct-2020

Structure

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Conserved Features/Sites?
PubMed References ?

Zn binding siteputative

Feature 1: Zn binding site [ion binding site], 8 residue positions

Conserved feature residue pattern:C C C C H C C C

Click to see conserved feature residue pattern help

Evidence:

Comment:based on the structures of other related PHD fingers having two zinc ions bound
Citation:PMID 19430464
Citation:PMID 20567261
Comment:The PHD zinc finger is characterized as Cys4HisCys3
Citation:PMID 7583761
Citation:PMID 7701562
Citation:PMID 21514168

Scroll to Sequence Alignment Display

Sequence Alignment

include consensus sequence

Format: Row Display: Color Bits: Type Selection:

Feature 1          #  #                    #  #    #  #                             #  #
Q9S736        227 MCVICNKFdf------avNTCRWIGCDVCSHWTHTDCAIrdgeismgv----spksvsgmgEMLFKCRAC 286  thale cress
NP_191909     837 MCLVCSNFdm------asNTCSWVGCDVCLHWCHTDCGIkesyirngi----nasgapgmtEMQFHCVAC 896  thale cress
NP_563958     438 MCPVCLRFds------asNTCSWVGCDVCSHWCHAACGIqknlikpgh----slkgqrgttEMMFHCIGC 497  thale cress
Q9LUB7        228 MCTICNKFdf------svNTCRWIGCDLCSHWTHTDCAIrdgqittgss---aknntsgpgEIVFKCRAC 288  thale cress
XP_002615478   10 HCDACGSDa---------DISSWIFCDICRHWTHTACASlsdk--------------evgdISSYHCAKC 56   Clavispora lusitaniae A...
ERZ98422       11 KCPLCANKqrlvplwfqeNTETWIKCDICNVWCHASCLKlpse--------------ecdrIDEYHCPNC 66   Rhizophagus irregularis...
ABK24532      282 MCVICSKFdf------evNTCRWVGCDTCSHWTHTDCAIragqismgt----slkgvagssEMLFRCRAC 341  Sitka spruce
XP_001758332  217 MCVMCSKFdf------daNTFRWLGCDVCSHWTHSDCAMrsgtismgvstkagsdrdsnscELIFRCRAC 280  Physcomitrella patens

Citing CDD

Jiyao W et al.(2023). "The conserved domain database in 2023.", Nucleic Acids Res. 51(D1):D384-D388.

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