Conserved Protein Domain Family
PHD_Hop1p_like
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cd15558: PHD_Hop1p_like 
PHD finger found in Schizosaccharomyces pombe meiosis-specific protein hop1 (Hop1p) and similar proteins
Fission yeast Hop1p, also termed linear element-associated protein hop1, is an S. pombe homolog of the synaptonemal complex (SC)-associated protein Hop1 in Saccharomyces cerevisiae. In contrast to S. cerevisiae, S. pombe forms thin threads, known as linear elements (LinEs), in meiotic nuclei, instead of a canonical synaptonemal complex. LinEs contain Rec10 protein and are evolutionary relics of SC axial elements. Fission yeast Hop1p is a linear element (LinE)-associated protein. It also associates with Rec10, which plays a role in recruiting the recombination machinery to chromatin. Hop1p contains an N-terminal HORMA (for Hop1p, Rev7p, and MAD2) domain and a C-terminal plant homeodomain (PHD) finger.
Links
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Statistics
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PSSM-Id: 277033
Aligned: 8 rows
Threshold Bit Score: 95.5895
Created: 6-Mar-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Zn binding siteputative
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C [CH] H [CH] C [CH]Click to see conserved feature residue pattern help
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1         # #            #  #    #  #                #  #
Q9P7P2       336 NCECGDste-dsEMFQCErCDGWVHCACYGFesdsdpRQPNQLLCYTC 382  Schizosaccharomyces pombe 972h-
EMR09970     304 RCECGDvsedsgDMIQCYvCQSWVHAWCYGFisgndeRLPDDHSCYSC 351  Pneumocystis murina B123
XP_002564254 528 RCECNTwyfkpsKSIQCAnCKEYQHTLCYGYysakdtRIPDIHYCYTC 575  Penicillium chrysogenum Wisconsin 54-1255
GAA87927     464 RCQCGWdge-eeAMAQCAfCQTRQHLLCYGYedahdpRVPDIHACYPC 510  Aspergillus kawachii IFO 4308
EGG12021     630 MCECKDwhd-diAMIMCErCSRWRHLSCYGYksikdlRIPIKFECFRC 676  Melampsora larici-populina 98AG31
EMS25327     536 ACECGDksd-dgGMICCSnCEVWKHAACYGFetvkdsRIPDVFVCYHC 582  Rhodosporidium toruloides NP11
EMC97773     436 LCQCGQtne-dgDMVQCAfCDTWQHLPCYGFtgsadqRLPQDHVCYRC 482  Baudoinia compniacensis UAMH 10762
GAD92959     447 RCQCSWnge-epGMIKCSfCHTYQHSLCYGFinptdpRLPETHACYRC 493  Byssochlamys spectabilis No. 5

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