Conserved Protein Domain Family
PHD2_PHF10
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cd15529: PHD2_PHF10 
PHD finger 2 found in PHD finger protein 10 (PHF10) and similar proteins
PHF10, also termed BRG1-associated factor 45a (BAF45a), or XAP135, is a ubiquitously expressed transcriptional regulator that is required for maintaining the undifferentiated status of neuroblasts. It contains a SAY (supporter of activation of yellow) domain and two adjacent plant homeodomain (PHD) fingers. This model corresponds to the second PHD finger.
Links
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Statistics
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PSSM-Id: 277004
Aligned: 17 rows
Threshold Bit Score: 75.4204
Created: 12-Aug-2013
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Zn binding siteputative
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C [CH] H [CH] C [CH]Click to see conserved feature residue pattern help
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1          #  #           #  #    #  #            #  #
Q8WUB8        435 TCIICGQphhEEEMMFCDmCDRGYHTFCVGLgaIPSGRWICDCC 478  human
Q63ZP1        443 TCIICGQphhEEEMMFCDtCDRGYHTFCVGLgaLPSGRWICDCC 486  African clawed frog
EMP25152      406 TCIICGQphhEEEMMFCDvCDRGYHTFCVGLgaIPSGRWICDCC 449  green seaturtle
Q6NWE1        427 TCTVCQQphhEEEMMFCDkCDRGFHTFCVGMdsIPMGCWVCDLC 470  zebrafish
XP_785947     903 TCSQCGDpthEDKMMFCDkCDRGYHTFCVGLtdIPTGNWLCPTC 946  purple urchin
ELT95254      616 MCAKCNDagdEEKMMFCDhCDRGFHTFCLGLrvIPTGRWVCPMC 659  Capitella sp. I Grassle & Grassle, 1976
XP_002166105   52 VCTECLAphdEHEMMFCDnCDRGYHSYCVGVkeIPKGRWVCNRC 95   green hydra
EEC00197      285 MCNICMAtdnEEKMMFCDrCDRGYHSFCVGMksVPAGRWICRLC 328  black-legged tick
Q9VWF2       1750 CCIKCRSsqrPGKMLYCEqCDRGYHIYCLGLrtVPDGRWSCERC 1793 fruit fly
EHJ68865     2201 TCCACSRpadDDKMLFCDlCDRGFHIYCVGLhtVPNGRWHCVEC 2244 monarch butterfly

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