Conserved Protein Domain Family
PHD1_PHF10
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cd15528: PHD1_PHF10 
PHD finger 1 found in PHD finger protein 10 (PHF10) and similar proteins
PHF10, also termed BRG1-associated factor 45a (BAF45a), or XAP135, is a ubiquitously expressed transcriptional regulator that is required for maintaining the undifferentiated status of neuroblasts. It contains a SAY (supporter of activation of yellow) domain and two adjacent plant homeodomain (PHD) fingers. This model corresponds to the first PHD finger.
Links
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Statistics
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PSSM-Id: 277003
Aligned: 20 rows
Threshold Bit Score: 73.9848
Created: 15-Aug-2013
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Zn binding siteputative
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C [CH] H [CH] C [CH]Click to see conserved feature residue pattern help
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1          #  #                   #  #    #  #                 #  #
Q8WUB8        379 ICGICLKGkesnk--kgkaeSLIHCSQCEnsGHPSCLDMtmelvsMIKTYPWQCMEC 433  human
ESO87689      256 TCRRCEIKnknkkrirrikeEIINCSECGagGHPTCLELteemvgVIQTYPWQCMEC 312  owl limpet
XP_002113767  323 SCGVCFASeyvnd--lgeieELIKCSQCGslTHPTCLELtpemvkVIQTYHWQCMDC 377  Trichoplax adhaerens
XP_005091425  720 KCRICKQRstkee---rkndRLVKCAQCGkiGHMSCLDLteelvaVIKTYPWQCMEC 773  California sea hare
ESN96294      304 RCGMCSQTtknky---nepdDLIKCNTCNvsNHPGCLGLsaemvpMIKTYDWQCMEC 357  Helobdella robusta
XP_002399348  232 VCKVCNNVdask-----egeELISCSECGkvGHVTCLDIlpemavAIKSYRWQCMEC 283  black-legged tick
EYC43459      377 KCSSCDELqke-------geVFIRCVSCHmqAHASCLEMsdemvaCVATYPWQCIEC 426  Ancylostoma ceylanicum
XP_002165676    2 SCKFCEADsn---------eEQIQCATCKgmCHPSCLELpkhiipVVRTYDWQCNDC 49   Hydra vulgaris
XP_003748125  275 MCKNCEQDlp---------gLMFRCSDCKkwSHLRCLELpsaepeYLKKYPWQCMEC 322  western predatory mite
EGT57962      529 NCYACDIAg----------gNMICCAECEivYHPECIEMpdrmvrVVKSYEWNCIEC 575  Caenorhabditis brenneri

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